2012
Skin symptoms in bakery and auto body shop workers: associations with exposure and respiratory symptoms
Arrandale V, Meijster T, Pronk A, Doekes G, Redlich CA, Holness DL, Heederik D. Skin symptoms in bakery and auto body shop workers: associations with exposure and respiratory symptoms. International Archives Of Occupational And Environmental Health 2012, 86: 167-175. PMID: 22411214, PMCID: PMC3555349, DOI: 10.1007/s00420-012-0760-x.Peer-Reviewed Original ResearchConceptsAuto body shop workersExposure-response relationshipRespiratory symptomsSkin symptomsItchy skinShop workersBakery workersPossible exposure-response relationshipSignificant exposure-response associationsExposure-response associationsRespiratory outcomesMean ageDry skinSkin exposureSymptomsAverage exposureStatistical significanceWheat allergensSkinExposureAssociationPrevious studiesResultsDataMethodsDataWorkers
2008
Skin Exposure to Aliphatic Polyisocyanates in the Auto Body Repair and Refinishing Industry: III. A Personal Exposure Algorithm
Liu Y, Stowe MH, Bello D, Sparer J, Gore RJ, Cullen MR, Redlich CA, Woskie SR. Skin Exposure to Aliphatic Polyisocyanates in the Auto Body Repair and Refinishing Industry: III. A Personal Exposure Algorithm. Annals Of Work Exposures And Health 2008, 53: 33-40. PMID: 19011126, PMCID: PMC2638551, DOI: 10.1093/annhyg/men070.Peer-Reviewed Original ResearchMeSH KeywordsAlgorithmsAutomobilesEnvironmental MonitoringHumansOccupational ExposurePolyurethanesSkinConceptsPersonal protective equipmentSkin exposureExposure metricsAuto body shop workersExposure indexUse of PPEExposure-response relationshipJob title categoriesAuto Body RepairIsocyanate asthmaExposure algorithmSemiquantitative algorithmSkin areasProtective equipmentSuch exposureExposure dataSpearman correlationShop workersExposure indicatorsOffice workersPositive Spearman correlationAuto body shopsExposureTask-based dataWork diariesComparison of Task-Based Exposure Metrics for an Epidemiologic Study of Isocyanate Inhalation Exposures Among Autobody Shop Workers
Woskie SR, Bello D, Gore RJ, Stowe MH, Eisen EA, Liu Y, Sparer JA, Redlich CA, Cullen MR. Comparison of Task-Based Exposure Metrics for an Epidemiologic Study of Isocyanate Inhalation Exposures Among Autobody Shop Workers. Journal Of Occupational And Environmental Hygiene 2008, 5: 588-598. PMID: 18615291, DOI: 10.1080/15459620802275429.Peer-Reviewed Original ResearchConceptsQuantitative exposure metricsOccupational exposure limitsEpidemiologic studiesExposure metricsRespirator useCross-week changesExposure-response analysisTime-weighted average exposureShop workersExposure assessmentPersonal daily exposureMagnitude of associationOccupational epidemiologic studiesWorkplace protection factorsQuantitative exposure assessmentTask-based exposure assessmentRespiratory functionInhalation exposureDaily exposureAverage exposureRisk estimatesExposure misclassificationQuantitative exposureSpearman correlationComparison of tasksSkin Exposure to Aliphatic Polyisocyanates in the Auto Body Repair and Refinishing Industry: II. A Quantitative Assessment
Bello D, Redlich CA, Stowe MH, Sparer J, Woskie SR, Streicher RP, Hosgood HD, Liu Y. Skin Exposure to Aliphatic Polyisocyanates in the Auto Body Repair and Refinishing Industry: II. A Quantitative Assessment. Annals Of Work Exposures And Health 2008, 52: 117-124. PMID: 18209009, DOI: 10.1093/annhyg/mem066.Peer-Reviewed Original ResearchConceptsSkin exposureUnprotected skinAuto body shop workersAuto Body RepairRespiratory exposureSkin areasExposure dataShop workersSkin samplingSkinExposureWipe samplesUnpaired samplesHigh concentrationsPPEGm loadYale studyHigh levelsBody repairAsthmaMajor contributorLevelsQuantitative assessmentForearmSensitization
2007
Skin Exposure to Aliphatic Polyisocyanates in the Auto Body Repair and Refinishing Industry: A Qualitative Assessment
LIU Y, BELLO D, SPARER JA, STOWE MH, GORE RJ, WOSKIE SR, CULLEN MR, REDLICH CA. Skin Exposure to Aliphatic Polyisocyanates in the Auto Body Repair and Refinishing Industry: A Qualitative Assessment. Annals Of Work Exposures And Health 2007, 51: 429-439. PMID: 17602207, DOI: 10.1093/annhyg/mem021.Peer-Reviewed Original ResearchConceptsAuto body shop workersSkin exposureHigh-performance liquid chromatographyShop workersHigher positive rateAuto Body RepairPositive surface samplesPositive sample rateEpidemiologic studiesUnprotected skinRespiratory exposurePercent of samplesSensitive high-performance liquid chromatographyLatex glovesScale 0Exposure dataExposure determinantsSkin samplesQuantitative high-performance liquid chromatographyNational InstituteOccupational SafetyAuto body shopsExposureMajor determinantPositive rateSlow Curing of Aliphatic Polyisocyanate Paints in Automotive Refinishing: A Potential Source for Skin Exposure
Bello D, Sparer J, Redlich CA, Ibrahim K, Stowe MH, Liu Y. Slow Curing of Aliphatic Polyisocyanate Paints in Automotive Refinishing: A Potential Source for Skin Exposure. Journal Of Occupational And Environmental Hygiene 2007, 4: 406-411. PMID: 17474030, DOI: 10.1080/15459620701341199.Peer-Reviewed Original Research
2006
Respiratory Protection from Isocyanate Exposure in the Autobody Repair and Refinishing Industry
Liu Y, Stowe MH, Bello D, Woskie SR, Sparer J, Gore R, Youngs F, Cullen MR, Redlich CA. Respiratory Protection from Isocyanate Exposure in the Autobody Repair and Refinishing Industry. Journal Of Occupational And Environmental Hygiene 2006, 3: 234-249. PMID: 16574607, DOI: 10.1080/15459620600628704.Peer-Reviewed Original ResearchConceptsWorkplace protection factorsIsocyanate exposureHalf-facepiece respiratorsRespiratory protectionFit factorsRespiratory protection programTotal isocyanate groupRespirator Fit FactorsOrganic vapor cartridgesShort-term exposure limitNegative pressureGM concentrationsPriming activitySignificant differencesExposure limitsUse trainingExposureRespiratorsProtection factorSecond testWorkersPortaCount
2005
A laboratory investigation of the effectiveness of various skin and surface decontaminants for aliphatic polyisocyanates
Bello D, Woskie SR, Streicher RP, Stowe MH, Sparer J, Redlich CA, Cullen MR, Liu Y. A laboratory investigation of the effectiveness of various skin and surface decontaminants for aliphatic polyisocyanates. Environmental Science Processes & Impacts 2005, 7: 716-721. PMID: 15986052, DOI: 10.1039/b503807c.Peer-Reviewed Original Research
2004
Determinants of Isocyanate Exposures in Auto Body Repair and Refinishing Shops
Woskie S, Sparer J, Gore R, Stowe M, Bello D, Liu Y, Youngs F, Redlich C, Eisen E, Cullen M. Determinants of Isocyanate Exposures in Auto Body Repair and Refinishing Shops. Annals Of Work Exposures And Health 2004, 48: 393-403. PMID: 15148052, DOI: 10.1093/annhyg/meh021.Peer-Reviewed Original Research
2002
Diisocyanate‐exposed auto body shop workers: A one‐year follow‐up
Redlich CA, Stowe MH, Coren BA, Wisnewski AV, Holm CT, Cullen MR. Diisocyanate‐exposed auto body shop workers: A one‐year follow‐up. American Journal Of Industrial Medicine 2002, 42: 511-518. PMID: 12439874, DOI: 10.1002/ajim.10143.Peer-Reviewed Original ResearchConceptsHealthy worker effectAuto body shop workersWorker effectHexamethylene diisocyanate exposureHistory of asthmaLower asthma prevalenceCross-sectional studyDiisocyanate exposureOccupational asthmaAsthma prevalenceImmunologic responseLow prevalenceAsthmaOne-yearHigh job turnover ratesShop workersEpisodic exposureSignificant differencesAuto body shopsPrevalenceEffect of HDISignificant changesExposureSymptomsIgG
2001
Subclinical immunologic and physiologic responses in hexamethylene diisocyanate‐exposed auto body shop workers
Redlich C, Stowe M, Wisnewski A, Eisen E, Karol M, Lemus R, Holm C, Chung J, Sparer J, Liu Y, Woskie S, Appiah‐Pippim J, Gore R, Cullen M. Subclinical immunologic and physiologic responses in hexamethylene diisocyanate‐exposed auto body shop workers. American Journal Of Industrial Medicine 2001, 39: 587-597. PMID: 11385643, DOI: 10.1002/ajim.1058.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAir Pollutants, OccupationalAnalysis of VarianceAsthmaAutomobilesChi-Square DistributionCross-Sectional StudiesCyanatesEpidemiologic StudiesFemaleHumansIsocyanatesMaleMiddle AgedOccupational DiseasesOccupational ExposurePaintStatistics, NonparametricSurveys and QuestionnairesConceptsAuto body shop workersDiisocyanate asthmaLymphocyte proliferationHost risk factorsShortness of breathShop workersMethacholine responsivenessMethacholine challengeChest tightnessDiisocyanate exposureOccupational asthmaImmunologic responseRisk factorsPhysiologic changesImmune responseEpidemiologic studiesSurveillance studyPhysiologic responsesAsthmaOvert casesSymptomsExposure dataEpisodic exposureAuto body shopsExposure
2000
Qualitative assessment of isocyanate skin exposure in auto body shops: A pilot study
Liu Y, Sparer J, Woskie S, Cullen M, Chung J, Holm C, Redlich C. Qualitative assessment of isocyanate skin exposure in auto body shops: A pilot study. American Journal Of Industrial Medicine 2000, 37: 265-274. PMID: 10642416, DOI: 10.1002/(sici)1097-0274(200003)37:3<265::aid-ajim4>3.0.co;2-o.Peer-Reviewed Original ResearchConceptsSkin exposurePersonal protective equipmentRespiratory sensitizationAuto body shopsLatex glovesProtective equipmentImportant risk factorEnvironmental surfacesRisk factorsAnimal studiesPilot studySkin protectionWorkers' skinAsthmaFrequent contactExposureSensitizationPotential relationshipSkin surfaceSkinGlovesFurther researchQualitative assessmentQualitative detectionPainting sessions