2021
Ketogenic Diets Induced Glucose Intolerance and Lipid Accumulation in Mice with Alterations in Gut Microbiota and Metabolites
Li Y, Yang X, Zhang J, Jiang T, Zhang Z, Wang Z, Gong M, Zhao L, Zhang C. Ketogenic Diets Induced Glucose Intolerance and Lipid Accumulation in Mice with Alterations in Gut Microbiota and Metabolites. MBio 2021, 12: 10.1128/mbio.03601-20. PMID: 33785628, PMCID: PMC8092315, DOI: 10.1128/mbio.03601-20.Peer-Reviewed Original ResearchConceptsKetogenic dietGut microbiotaProportion of fatLipid metabolismGlucose intoleranceInsulin resistanceFat accumulationMouse trialsNeurodegenerative diseasesLipid accumulationMore fat accumulationInduced glucose intoleranceLipid metabolism disordersAffected lipid metabolismMetabolism disordersMetabolic disordersGlucose homeostasisGlucose metabolismSource of fatHuman studiesHigh fatTreatment of diseasesMiceBeneficial effectsWeight loss
2020
Lactobacillus Mucosae Strain Promoted by a High-Fiber Diet in Genetic Obese Child Alleviates Lipid Metabolism and Modifies Gut Microbiota in ApoE-/- Mice on a Western Diet
Jiang T, Wu H, Yang X, Li Y, Zhang Z, Chen F, Zhao L, Zhang C. Lactobacillus Mucosae Strain Promoted by a High-Fiber Diet in Genetic Obese Child Alleviates Lipid Metabolism and Modifies Gut Microbiota in ApoE-/- Mice on a Western Diet. Microorganisms 2020, 8: 1225. PMID: 32806628, PMCID: PMC7464838, DOI: 10.3390/microorganisms8081225.Peer-Reviewed Original ResearchWestern dietHigh-fiber dietGut microbiotaApoE-/- miceModifies gut microbiotaTreatment of hyperlipidemiaSevere lipid accumulationGut microbiota structureProbiotic candidate strainSupplementation of probioticsNext-generation probioticsMetabolic endotoxemiaAortic sinusHuman-derived strainsHyperlipidemiaTherapeutic methodsLipid metabolismAtherosclerosisLipid accumulationMiceSelection of candidatesApoEMicrobiota structureDietProbiotics