1983
Evidence of a treatment dose response in acute nonlymphocytic leukemias which occur after therapy of non-Hodgkin's lymphoma.
Greene M, Young R, Merrill J, DeVita V. Evidence of a treatment dose response in acute nonlymphocytic leukemias which occur after therapy of non-Hodgkin's lymphoma. Cancer Research 1983, 43: 1891-8. PMID: 6572558.Peer-Reviewed Original ResearchConceptsRisk of acute nonlymphocytic leukemiaNon-Hodgkin's lymphomaAcute nonlymphocytic leukemiaCases of acute nonlymphocytic leukemiaNonlymphocytic leukemiaTherapy of non-Hodgkin's lymphomaNon-Hodgkin lymphoma cohortNon-Hodgkin's lymphoma patientsSingle-modality therapyModel of leukemogenesisCase-control studyCumulative radiation dosePatients per yearOptimum patient managementHemibody radiationLeukemogenic therapyNational Cancer InstituteChemotherapy durationHistological subtypesChemotherapy doseTreatment regimensBone marrowTotal bodyPatient managementTherapy
1982
Histologic Progression in Non-Hodgkin’s Lymphoma
Hubbard S, Chabner B, DeVita V, Simon R, Berard C, Jones R, Garvin A, Canellos G, Osborne C, Young R. Histologic Progression in Non-Hodgkin’s Lymphoma. Blood 1982, 59: 258-264. DOI: 10.1182/blood.v59.2.258.258.Peer-Reviewed Original ResearchNodular lymphomaHistological progressionLymphoma patientsHistiocytic cell typesProlonged disease-free survivalNon-Hodgkin's lymphoma patientsAssociated with prolonged survivalCell typesIntensive combination chemotherapyNon-Hodgkin's lymphomaDisease-free survivalResponse to chemotherapyNon-HodgkinCombination chemotherapyDiffuse histologyIntensive chemotherapyClinical courseBiopsy specimensProlonged survivalWorsened prognosisLymphomaNodular patternBiopsyClinical trialsDrug treatment
1980
The Rappaport classification of non-Hodgkin's lymphomas: a closer look using other proposed classifications.
Garvin A, Simon R, Young R, DeVita V, Berard C. The Rappaport classification of non-Hodgkin's lymphomas: a closer look using other proposed classifications. Seminars In Oncology 1980, 7: 234-43. PMID: 6998002.Peer-Reviewed Original ResearchConceptsLukes-Collins systemNon-Hodgkin's lymphomaLukes-CollinsClassification of non-Hodgkin's lymphomasClinical management of patientsAggressive combination chemotherapyDiffuse histiocytic lymphomaHomogeneous group of patientsManagement of patientsGroup of patientsB symptomsLymphocytic lymphomaCentroblastic-centrocyticCombination chemotherapyDiffuse lymphomaLymphoblastic lymphomaPlasmacytoid differentiationKiel classificationRappaport classificationNodular lymphomaHistiocytic lymphomaRetrospective reviewFollicular patternClinicopathologic entityYounger patientsNodular Histiocytic Lymphoma: An Aggressive Nodular Lymphoma With Potential for Prolonged Disease-Free Survival
Osborne C, Norton L, Young R, Garvin A, Simon R, Berard C, Hubbard S, DeVita V. Nodular Histiocytic Lymphoma: An Aggressive Nodular Lymphoma With Potential for Prolonged Disease-Free Survival. Blood 1980, 56: 98-103. DOI: 10.1182/blood.v56.1.98.98.Peer-Reviewed Original ResearchNodular histiocytic lymphomasDiffuse histiocytic lymphomaHistiocytic lymphomaNodular lymphomaPathological stageProlonged disease-free survivalNatural historyDisease-free survivalLymph node biopsyNon-Hodgkin's lymphomaSubtypes of lymphomaTreated with cyclophosphamideLymph node examinationLymph node histologyGroup of patientsLong-term survivorsNode biopsyCombination chemotherapyNode examinationLiver involvementNode histologyLymphomaTherapeutic strategiesPatientsLymphNodular histiocytic lymphoma: an aggressive nodular lymphoma with potential for prolonged disease-free survival.
Osborne C, Norton L, Young R, Garvin A, Simon R, Berard C, Hubbard S, DeVita V. Nodular histiocytic lymphoma: an aggressive nodular lymphoma with potential for prolonged disease-free survival. Blood 1980, 56: 98-103. PMID: 6992889, DOI: 10.1182/blood.v56.1.98.bloodjournal56198.Peer-Reviewed Original ResearchConceptsNodular histiocytic lymphomasDiffuse histiocytic lymphomaHistiocytic lymphomaNodular lymphomaPathological stageProlonged disease-free survivalNatural historyLymph node biopsyNon-Hodgkin's lymphomaDisease-free survivalSubtypes of lymphomaTreated with cyclophosphamideLymph node examinationLymph node histologyGroup of patientsLong-term survivorsCombination chemotherapyNode biopsyNode examinationLiver involvementNode histologyLymphomaTherapeutic strategiesPatientsLymph
1977
Sequential staging in non-Hodgkin's lymphoma.
Chabner B, Johnson R, DeVita V, Canellos G, Hubbard S, Johnson S, Young R. Sequential staging in non-Hodgkin's lymphoma. Journal Of The National Cancer Institute 1977, 61: 993-7. PMID: 902262.Peer-Reviewed Original ResearchConceptsNon-Hodgkin's lymphomaInvolvement of bone marrowBone marrow biopsyDiffuse lymphocytic lymphomaType of lymphomaPortal lymph nodesNon-surgical phaseCompletion of stagingNegative lymphangiogramLymphocytic lymphomaMarrow biopsyPositive lymphangiogramHistiocytic lymphomaAbdominal nodesLiver biopsyLymph nodesBone marrowLymphomaPhase of stagingNodular typeStage IIIStage IPatientsResults of stagingLaparotomy
1976
Sequential nonsurgical and surgical staging of non-Hodgkin's lymphoma.
Chabner B, Johnson R, Young R, Canellos G, Hubbard S, Johnson S, DeVita V. Sequential nonsurgical and surgical staging of non-Hodgkin's lymphoma. Annals Of Internal Medicine 1976, 85: 149-54. PMID: 782309, DOI: 10.7326/0003-4819-85-2-149.Peer-Reviewed Original ResearchConceptsNon-Hodgkin's lymphomaStaging of non-Hodgkin's lymphomaStaging laparotomyLiver biopsyStage III or stage IV diseasePresence of disseminated diseaseDiagnostic proceduresStage IV diseaseBone marrow biopsyPercutaneous liver biopsySequence of diagnostic proceduresNegative lymphangiogramIV diseaseSurgical stagingDisseminated diseaseConsecutive patientsLocalized diseaseNodular lymphomaPositive lymphangiogramHistiocytic lymphomaStaging procedureLymphomaStage IPatientsNonsurgical proceduresEffect of splenectomy on tolerance to combination chemotherapy in patients with lymphoma.
Ihde D, DeVita V, Canellos G, Young R. Effect of splenectomy on tolerance to combination chemotherapy in patients with lymphoma. Blood 1976, 47: 211-22. PMID: 1244920, DOI: 10.1182/blood.v47.2.211.bloodjournal472211.Peer-Reviewed Original ResearchConceptsTolerance to combination chemotherapyCombination chemotherapyHodgkin's diseasePlatelet countControl patientsBone marrow lymphomaSplenectomy per seCycles of therapyNon-Hodgkin's lymphomaCycles of treatmentMatched control patientsPortion of patientsEffect of splenectomyLymphoma patientsInitial treatmentStaging procedureLymphomaTotal doseSplenectomyChemotherapyLeukocyte countPatientsHodgkinLeukocytesPlateletCentral nervous system complications in patients with diffuse histiocytic and undifferentiated lymphoma: leukemia revisited.
Bunn P, Schein P, Banks P, DeVita V. Central nervous system complications in patients with diffuse histiocytic and undifferentiated lymphoma: leukemia revisited. Blood 1976, 47: 3-10. PMID: 1106798, DOI: 10.1182/blood.v47.1.3.bloodjournal4713.Peer-Reviewed Original ResearchConceptsLeptomeningeal lymphomaCentral nervous systemHistologic types of non-Hodgkin's lymphomasProgression of systemic diseaseCentral nervous system complicationsCentral nervous system therapyProphylactic CNS therapySite of relapseBone marrow involvementNon-Hodgkin's lymphomaIntrathecal drug administrationPatient's clinical courseCerebrospinal fluid cytologyResponse to therapyNervous system complicationsNervous system therapyBone marrow cavityUndifferentiated lymphomaMarrow involvementClinical remissionSystemic therapyCNS therapyClinical courseHistological typeSystemic complicationsCentral Nervous System Complications in Patients With Diffuse Histiocytic and Undifferentiated Lymphoma: Leukemia Revisited
Bunn P, Schein P, Banks P, DeVita V. Central Nervous System Complications in Patients With Diffuse Histiocytic and Undifferentiated Lymphoma: Leukemia Revisited. Blood 1976, 47: 3-10. DOI: 10.1182/blood.v47.1.3.3.Peer-Reviewed Original ResearchLeptomeningeal lymphomaCentral nervous systemHistologic types of non-Hodgkin's lymphomasProgression of systemic diseaseCentral nervous system complicationsCentral nervous system therapyProphylactic CNS therapySite of relapseBone marrow involvementNon-Hodgkin's lymphomaIntrathecal drug administrationPatient's clinical courseCerebrospinal fluid cytologyResponse to therapyNervous system complicationsNervous system therapyBone marrow cavityUndifferentiated lymphomaMarrow involvementClinical remissionSystemic therapyCNS therapyClinical courseHistological typeSystemic complications