2022
Response of Human Toll–Like Receptor 2 During the Infection of Leptospirosis
Kappagoda C, Senavirathna I, Warnasekara J, Srimantha S, De Silva N, Agampodi S. Response of Human Toll–Like Receptor 2 During the Infection of Leptospirosis. International Journal Of Infectious Diseases 2022, 116: s71. DOI: 10.1016/j.ijid.2021.12.167.Peer-Reviewed Original ResearchToll-like receptor2Human TLR2 geneTLR2 geneMouse modelToll-like receptor 2Human Toll-like receptor 2Results 64 patientsInnate immune responsePathogenic Leptospira sppGene expression analysisImmune responseStudy populationReceptor 2Receptor responsesTLR2 regulationPatientsLeptospirosisLeptospira sppNew therapeuticsWhole bloodGene expression studiesGene amplificationReverse transcriptaseInfectionTotal RNA
2019
Baseline titres of O, H and AH agglutinins to Salmonella Typhi and Paratyphi A in blood donors in Sri Lanka.
Illapperuma S, Corea E, Agampodi S. Baseline titres of O, H and AH agglutinins to Salmonella Typhi and Paratyphi A in blood donors in Sri Lanka. Sri Lankan Journal Of Infectious Diseases 2019, 9: 32-41. DOI: 10.4038/sljid.v9i1.8230.Peer-Reviewed Original ResearchBaseline titreEnteric feverBlood donorsStudy populationBaseline Widal titresWidal test resultsYears age groupHigher test positivitySri Lankan settingWidal titresTest positivitySri Lankan populationWidal testBlood culturesEndemic countriesO agglutininsParatyphi AAge groupsStudy participantsBlood bankTitresSerum samplesSalmonella OSalmonella typhiFever
2016
Prevalence of headache among school children in Polonnaruwa educational zone
Perera K, Wanigasinghe J, Agampodi S, de Silva U. Prevalence of headache among school children in Polonnaruwa educational zone. Sri Lanka Journal Of Child Health 2016, 45: 199-203. DOI: 10.4038/sljch.v45i3.8032.Peer-Reviewed Original ResearchPrevalence of migraineTension-type headachePrimary headachesType headacheInternational ClassificationInternational Headache Society's International ClassificationSlight female predominanceSchool childrenPrevalence of headacheStudy sampleDiagnosis of migraineObserved high prevalenceSelf-administered questionnaireUnclassified headacheMedian ageFemale predominanceClinical examinationSectional studyHeadache disordersSecondary causesHigh prevalenceStudy populationRecurrent headachesHeadacheMigraine
2013
Emergence of cutaneous leishmaniasis in Polonnaruwa, Sri Lanka 2008–2011
Sandanayaka R, Kahawita I, Gamage A, Siribaddana S, Agampodi S. Emergence of cutaneous leishmaniasis in Polonnaruwa, Sri Lanka 2008–2011. Tropical Medicine And International Health 2013, 19: 140-145. PMID: 24438012, DOI: 10.1111/tmi.12232.Peer-Reviewed Original ResearchConceptsCutaneous leishmaniasisAnnual incidenceMajority of patientsMean annual incidencePolonnaruwa districtDermatology unitClinical detailsGeneral HospitalStudy populationEpidemiology UnitUpper limbLeishmaniasis surveillanceCase incidenceLeishmaniasisPatientsStudy periodIncidenceCommon typeCase distributionLesionsMore malesHospitalPopulationPolonnaruwaSri Lanka
2012
Anaemia in pregnancy in the district of Anuradhapura, Sri Lanka – need for updating prevalence data and screening strategies
Chathurani U, Dharshika I, Galgamuwa D, Wickramasinghe N, Agampodi T, Agampodi S. Anaemia in pregnancy in the district of Anuradhapura, Sri Lanka – need for updating prevalence data and screening strategies. Ceylon Medical Journal 2012, 57: 101-6. PMID: 23086024, DOI: 10.4038/cmj.v57i3.4148.Peer-Reviewed Original ResearchConceptsPrevalence of anemiaMean corpuscular hemoglobin concentrationMean corpuscular volumePregnant womenMean corpuscular hemoglobinDistrict of AnuradhapuraHemoglobin concentrationAnemic pregnant womenMedian hemoglobin concentrationCorpuscular hemoglobin concentrationAnuradhapura districtHaemoglobin Colour ScaleAntenatal clinicSerum hemoglobinGestational ageThird trimesterAnemia prevalenceMethemoglobin methodClinical examinationStudy populationAnemiaCorpuscular volumePregnancyPrevalence dataCorpuscular hemoglobinInadequacy of the risk factor based approach to detect gestational diabetes mellitus
Dahanayaka N, Agampodi S, Ranasinghe O, Jayaweera P, Wickramasinghe W, Adhikari A, Chathurani H, Dissanayaka U. Inadequacy of the risk factor based approach to detect gestational diabetes mellitus. Ceylon Medical Journal 2012, 57: 5-9. PMID: 22453704, DOI: 10.4038/cmj.v57i1.4193.Peer-Reviewed Original ResearchConceptsGestational diabetes mellitusRisk factorsIADPSG criteriaPregnant womenDiabetes mellitusPrevalence of GDMOral glucose tolerance testCross-sectional descriptive studyEligible pregnant womenPregnancy Study GroupsGlucose tolerance testSectional descriptive studyPresent risk factorsGDM patientsGDM casesGestational ageWHO criteriaPlasma glucoseTolerance testStudy groupStudy populationDescriptive studyMedical officersHealth areaMellitus
2010
Prevalence of Mental Health Problems in Adolescent Schoolchildren in Galle District, Sri Lanka
Agampodi TC, Agampodi SB, Fonseka P. Prevalence of Mental Health Problems in Adolescent Schoolchildren in Galle District, Sri Lanka. Asia Pacific Journal Of Public Health 2010, 23: 588-600. PMID: 20460278, DOI: 10.1177/1010539509349866.Peer-Reviewed Original ResearchConceptsMental health problemsPrevalence of MHPsAdolescent schoolchildrenHealth problemsDescriptive cross-sectional studyCross-sectional studySelf-administered questionnaireStudy populationSinhalese versionPrevalenceDifficulties QuestionnaireStudy instrumentGalle districtMonthsSchoolchildrenPresent studyQuestionnaireSri Lanka
2009
Susceptibility of New Entrant University Students in Sri Lanka to Varicella Zoster Infection
Kurukulasooriya GM, Thevanesam V, Agampodi SB, Abeykoon AM, Amarasiri SP, Goonasekera KP. Susceptibility of New Entrant University Students in Sri Lanka to Varicella Zoster Infection. Asia Pacific Journal Of Public Health 2009, 22: 219-224. PMID: 19411280, DOI: 10.1177/1010539509334625.Peer-Reviewed Original ResearchConceptsVZV IgG antibodiesChicken poxIgG antibodiesVaricella-zoster virus infectionCross-sectional descriptive studyVaricella zoster infectionZoster virus infectionHistory of infectionSelf-reported historyZoster infectionMedian ageVZV infectionSeropositive rateSerological evaluationVirus infectionStudy populationNegative historyInfectionDescriptive studyInterquartile rangeUniversity of PeradeniyaAgeAntibodiesPresent studyYearsEvaluation of surveillance case definition in the diagnosis of leptospirosis, using the Microscopic Agglutination Test: a validation study
Dassanayake D, Wimalaratna H, Agampodi SB, Liyanapathirana VC, Piyarathna T, Goonapienuwala BL. Evaluation of surveillance case definition in the diagnosis of leptospirosis, using the Microscopic Agglutination Test: a validation study. BMC Infectious Diseases 2009, 9: 48. PMID: 19386085, PMCID: PMC2679753, DOI: 10.1186/1471-2334-9-48.Peer-Reviewed Original ResearchConceptsSurveillance case definitionMicroscopic agglutination testCase definitionNegative predictive valuePredictive valueClinical featuresMAT titresAgglutination testDays of feverAcute febrile illnessMethodsThe study populationTeaching Hospital KandyPositive predictive valueDiagnosis of leptospirosisPositive MAT resultsFebrile illnessMedical wardsResultsA totalHospital KandyStudy populationBlood samplesConclusionThis studyPatientsDiagnostic accuracyLeptospirosis