2003
Asymptomatic Infection with Borrelia burgdorferi
Steere A, Sikand V, Schoen R, Nowakowski J. Asymptomatic Infection with Borrelia burgdorferi. Clinical Infectious Diseases 2003, 37: 528-532. PMID: 12905137, DOI: 10.1086/376914.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedBorrelia burgdorferiDouble-Blind MethodFemaleHumansLyme DiseaseLyme Disease VaccinesMaleMiddle AgedPrevalenceTreatment Outcome
1998
Vaccination against Lyme Disease with Recombinant Borrelia burgdorferi Outer-Surface Lipoprotein A with Adjuvant
Steere A, Sikand V, Meurice F, Parenti D, Fikrig E, Schoen R, Nowakowski J, Schmid C, Laukamp S, Buscarino C, Krause D. Vaccination against Lyme Disease with Recombinant Borrelia burgdorferi Outer-Surface Lipoprotein A with Adjuvant. New England Journal Of Medicine 1998, 339: 209-215. PMID: 9673298, DOI: 10.1056/nejm199807233390401.Peer-Reviewed Original ResearchConceptsLyme diseaseSerologic testingVaccine efficacyAsymptomatic infectionLipoprotein AInjections of vaccineOuter surface lipoprotein AB. burgdorferi infectionFirst yearPlacebo recipientsPlacebo groupVaccine groupVaccine recipientsStudy entryRandomized trialsSystemic reactionsThird injectionBurgdorferi infectionEffective vaccineSkin lesionsReaction testingVaccineDefinite casesDiseaseInfection
1985
Successful Parenteral Penicillin Therapy of Established Lyme Arthritis
Steere A, Green J, Schoen R, Taylor E, Hutchinson G, Rahn D, Malawista S. Successful Parenteral Penicillin Therapy of Established Lyme Arthritis. New England Journal Of Medicine 1985, 312: 869-874. PMID: 3883177, DOI: 10.1056/nejm198504043121401.Peer-Reviewed Original ResearchMeSH KeywordsAdultArthritis, InfectiousClinical Trials as TopicDouble-Blind MethodFemaleHumansInjections, IntravenousLyme DiseaseMalePenicillin GConceptsLyme arthritisComplete resolutionDouble-blind placebo-controlled trialAttacks of arthritisIntravenous penicillin GParenteral penicillin therapyPlacebo-controlled trialPenicillin-treated patientsErythema chronicum migransMean followPenicillin therapyParenteral therapyParenteral penicillinIntraarticular corticosteroidsJoint fluidArthritisPatientsLyme spirocheteFurther experienceTherapyPenicillin GOptimal courseDaysCorticosteroidsPlacebo