2020
Secondary prevention of cardiovascular disease in China
Lu J, Zhang L, Lu Y, Su M, Li X, Liu J, Zhang H, Nasir K, Masoudi F, Krumholz H, Li J, Zheng X. Secondary prevention of cardiovascular disease in China. Heart 2020, 106: 1349-1356. PMID: 31980439, DOI: 10.1136/heartjnl-2019-315884.Peer-Reviewed Original ResearchMeSH KeywordsAdultAge FactorsAgedAlcohol DrinkingCardiovascular DiseasesChinaFemaleHealthy LifestyleHeart Disease Risk FactorsHumansHydroxymethylglutaryl-CoA Reductase InhibitorsMaleMiddle AgedPlatelet Aggregation InhibitorsRisk AssessmentRisk Reduction BehaviorSecondary PreventionSex FactorsSmoking CessationTime FactorsTreatment OutcomeConceptsSecondary prevention drugsIschemic heart diseaseCardiovascular diseasePrevention drugsIschemic strokeSecondary preventionAntiplatelet drugsCardiac Events Million Persons ProjectHistory of IHDMillion Persons ProjectSecondary prevention therapiesPopulation subgroupsMultivariable mixed modelsPublic health programsCommunities of ChinaCurrent smokersCurrent useMedication usePrevention therapyMultivariable analysisChina PatientHeart diseaseCurrent drinkersHealth programsDrugs
2019
P834Secondary prevention medications of cardiovascular diseases in China: findings from China PEACE million persons project
Lu J, Zhang L, Lu Y, Su M, Li X, Li J, Liu J, Zhang H, Nasir K, Masoudi F, Krumholz H, Zheng X. P834Secondary prevention medications of cardiovascular diseases in China: findings from China PEACE million persons project. European Heart Journal 2019, 40: ehz747.0433. DOI: 10.1093/eurheartj/ehz747.0433.Peer-Reviewed Original ResearchSecondary prevention medicationsIschemic heart diseasePrevention medicationsAnti-platelet drugsCardiovascular diseaseMultivariable mixed modelsIschemic strokePopulation subgroupsCardiac Events Million Persons ProjectHistory of IHDPrognosis of CVDMillion Persons ProjectHealth behavior factorsSecondary prevention drugsCause of deathCurrent usePublic health programsPersons ProjectNational Health CommissionCurrent smokersSecondary preventionMedication useMultivariable analysisChina PatientPrevention drugs
2018
Percutaneous Coronary Intervention in Patients Without Acute Myocardial Infarction in China
Lu Y, Zhang H, Wang Y, Zhou T, Welsh J, Liu J, Guan W, Li J, Li X, Zheng X, Spertus JA, Masoudi FA, Krumholz HM, Jiang L. Percutaneous Coronary Intervention in Patients Without Acute Myocardial Infarction in China. JAMA Network Open 2018, 1: e185446. PMID: 30646292, PMCID: PMC6324328, DOI: 10.1001/jamanetworkopen.2018.5446.Peer-Reviewed Original ResearchConceptsStable coronary artery diseaseAcute myocardial infarctionCoronary artery diseaseSeattle Angina QuestionnairePercutaneous coronary interventionClinical improvementSmall clinical improvementAngina symptomsUnstable anginaArtery diseaseHealth statusCoronary interventionSymptom burdenMyocardial infarctionSAQ scoresSAQ angina frequency scorePatient-reported health statusPercutaneous coronary intervention (PCI) proceduresSelf-reported health statusAngina frequency scoreMulticenter cohort studyGreater clinical improvementSubstantial clinical improvementIschemic heart diseaseCoronary intervention procedures
2017
Time for a New Approach to Studying Older People with Ischemic Heart Disease
Dodson JA, Chaudhry SI, Krumholz HM. Time for a New Approach to Studying Older People with Ischemic Heart Disease. Journal Of The American Geriatrics Society 2017, 65: 2349-2351. PMID: 28493548, PMCID: PMC5681380, DOI: 10.1111/jgs.14923.Peer-Reviewed Original ResearchConceptsIschemic heart disease
2012
2012 ACCF/AHA/ACP/AATS/PCNA/SCAI/STS Guideline for the Diagnosis and Management of Patients With Stable Ischemic Heart Disease
Fihn SD, Gardin JM, Abrams J, Berra K, Blankenship JC, Dallas AP, Douglas PS, Foody JM, Gerber TC, Hinderliter AL, King SB, Kligfield PD, Krumholz HM, Kwong RY, Lim MJ, Linderbaum JA, Mack MJ, Munger MA, Prager RL, Sabik JF, Shaw LJ, Sikkema JD, Smith CR, Smith SC, Spertus JA, Williams SV. 2012 ACCF/AHA/ACP/AATS/PCNA/SCAI/STS Guideline for the Diagnosis and Management of Patients With Stable Ischemic Heart Disease. Circulation 2012, 126: 3097-3137. PMID: 23166210, DOI: 10.1161/cir.0b013e3182776f83.Peer-Reviewed Original Research2012 ACCF/AHA/ACP/AATS/PCNA/SCAI/STS Guideline for the Diagnosis and Management of Patients With Stable Ischemic Heart Disease
Fihn SD, Gardin JM, Abrams J, Berra K, Blankenship JC, Dallas AP, Douglas PS, Foody JM, Gerber TC, Hinderliter AL, King SB, Kligfield PD, Krumholz HM, Kwong RY, Lim MJ, Linderbaum JA, Mack MJ, Munger MA, Prager RL, Sabik JF, Shaw LJ, Sikkema JD, Smith CR, Smith SC, Spertus JA, Williams SV, Anderson JL. 2012 ACCF/AHA/ACP/AATS/PCNA/SCAI/STS Guideline for the Diagnosis and Management of Patients With Stable Ischemic Heart Disease. Circulation 2012, 126: e354-e471. PMID: 23166211, DOI: 10.1161/cir.0b013e318277d6a0.Peer-Reviewed Original ResearchConceptsStable ischemic heart diseaseIschemic heart diseaseManagement of patientsHeart diseaseSTS guidelinesPatientsDiseaseDiagnosis2012 ACCF/AHA/ACP/AATS/PCNA/SCAI/STS Guideline for the Diagnosis and Management of Patients With Stable Ischemic Heart Disease: Executive Summary A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, and the American College of Physicians, American Association for Thoracic Surgery, Preventive Cardiovascular Nurses Association, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic Surgeons
Fihn SD, Gardin JM, Abrams J, Berra K, Blankenship JC, Dallas AP, Douglas PS, Foody JM, Gerber TC, Hinderliter AL, King SB, Kligfield PD, Krumholz HM, Kwong RY, Lim MJ, Linderbaum JA, Mack MJ, Munger MA, Prager RL, Sabik JF, Shaw LJ, Sikkema JD, Smith CR, Smith SC, Spertus JA, Williams SV. 2012 ACCF/AHA/ACP/AATS/PCNA/SCAI/STS Guideline for the Diagnosis and Management of Patients With Stable Ischemic Heart Disease: Executive Summary A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, and the American College of Physicians, American Association for Thoracic Surgery, Preventive Cardiovascular Nurses Association, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic Surgeons. Journal Of The American College Of Cardiology 2012, 60: 2564-2603. PMID: 23182124, DOI: 10.1016/j.jacc.2012.07.012.Peer-Reviewed Original ResearchAmerican CollegeAmerican Heart Association Task ForcePreventive Cardiovascular Nurses AssociationStable ischemic heart diseaseCardiology Foundation/American Heart Association Task ForceIschemic heart diseaseManagement of patientsThoracic surgeryHeart diseasePractice guidelinesCardiovascular AngiographyThoracic surgeonsSTS guidelinesA ReportNurses AssociationAmerican AssociationTask ForceAssociationGuidelinesPatientsSurgeryAngiographyDiseaseDiagnosisPhysiciansDiscontinuation of Antihyperglycemic Therapy After Acute Myocardial Infarction: Medical Necessity or Medical Error?
Lovig KO, Horwitz L, Lipska K, Kosiborod M, Krumholz HM, Inzucchi SE. Discontinuation of Antihyperglycemic Therapy After Acute Myocardial Infarction: Medical Necessity or Medical Error? The Joint Commission Journal On Quality And Patient Safety 2012, 38: 403-407. PMID: 23002492, PMCID: PMC3534988, DOI: 10.1016/s1553-7250(12)38051-3.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionLeft ventricular ejection fractionAntihyperglycemic therapyDiabetic patientsMyocardial infarctionMedical necessityOne-year mortalityDetailed chart reviewVentricular ejection fractionIschemic heart diseaseNational Medicare databaseMedical errorsAcademic medical centerQuality improvement opportunitiesChart reviewClinical characteristicsOlder patientsRecurrent hypoglycemiaEjection fractionMedicare databaseBlood glucoseHeart diseasePrincipal diagnosisCommunity hospitalMedical Center
2011
30-Day Readmission for Patients Undergoing Percutaneous Coronary Interventions in New York State
Hannan EL, Zhong Y, Krumholz H, Walford G, Holmes DR, Stamato NJ, Jacobs AK, Venditti FJ, Sharma S, King SB. 30-Day Readmission for Patients Undergoing Percutaneous Coronary Interventions in New York State. JACC Cardiovascular Interventions 2011, 4: 1335-1342. PMID: 22192374, DOI: 10.1016/j.jcin.2011.08.013.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionReadmission ratesUnique risk factorsRisk factorsCoronary interventionAdministrative databasesComplications of PCIPre-procedural risk factorsRepeat percutaneous coronary interventionChronic ischemic heart diseaseOverall readmission rateHigher readmission ratesIschemic heart diseaseLength of stayNew York State patientsRecognition of patientsDiagnostic risk factorsCost-effectiveness standpointPCI patientsPCI registryChest painHeart failureHospital readmissionHeart diseasePrincipal diagnosisNational and Regional Trends in Heart Failure Hospitalization and Mortality Rates for Medicare Beneficiaries, 1998-2008
Chen J, Normand SL, Wang Y, Krumholz HM. National and Regional Trends in Heart Failure Hospitalization and Mortality Rates for Medicare Beneficiaries, 1998-2008. JAMA 2011, 306: 1669-1678. PMID: 22009099, PMCID: PMC3688069, DOI: 10.1001/jama.2011.1474.Peer-Reviewed Original ResearchConceptsHF hospitalization ratesHeart failure hospitalizationHospitalization ratesMortality rateFailure hospitalizationHeart failure hospitalization ratesPrincipal discharge diagnosis codeOne-year mortality rateDischarge diagnosis codesIschemic heart diseaseAcute care hospitalsService Medicare beneficiariesLower ratesBlack menHF hospitalizationPatient demographicsCare hospitalDiagnosis codesHeart diseaseRisk factorsMedicare beneficiariesHospitalizationStudy periodMortalityNational mean
2010
Variation in Recovery
Lichtman JH, Lorenze NP, D'Onofrio G, Spertus JA, Lindau ST, Morgan TM, Herrin J, Bueno H, Mattera JA, Ridker PM, Krumholz HM. Variation in Recovery. Circulation Cardiovascular Quality And Outcomes 2010, 3: 684-693. PMID: 21081748, PMCID: PMC3064946, DOI: 10.1161/circoutcomes.109.928713.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionYoung AMI patientsAMI patientsYoung womenHeart diseaseSex differencesExcess mortality riskIschemic heart diseaseRisk stratification modelPsychosocial risk factorsYears of ageQuality of careComparison cohortPrognostic factorsPrognostic importanceAMI populationMyocardial infarctionRisk factorsObservational studyMortality riskHigh riskAMI eventsPatientsAge accountWomen
1999
Sex differences in the clinical care and outcomes of congestive heart failure in the elderly
Vaccarino V, Chen Y, Wang Y, Radford M, Krumholz H. Sex differences in the clinical care and outcomes of congestive heart failure in the elderly. American Heart Journal 1999, 138: 835-842. PMID: 10539813, DOI: 10.1016/s0002-8703(99)70007-4.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAngiotensin-Converting Enzyme InhibitorsAspirinBlood PressureCardiac CatheterizationConnecticutCoronary AngiographyDiureticsDrug Therapy, CombinationFemaleFollow-Up StudiesHeart FailureHumansMaleMyocardial RevascularizationPatient ReadmissionPlatelet Aggregation InhibitorsRetrospective StudiesSeverity of Illness IndexSex CharacteristicsStroke VolumeSurvival RateTreatment OutcomeConceptsHistory of hypertensionSystolic blood pressureHeart failureMortality rateBlood pressureHeart diseaseHigher systolic blood pressureLeft ventricular systolic functionSex differencesPrevious coronary heart diseaseSimilar hospital coursesVentricular systolic functionCongestive heart failureIschemic heart diseaseCoronary heart diseaseHospital courseElderly patientsReadmission ratesRehospitalization ratesSystolic functionMale patientsVentricular functionACE inhibitorsMultivariable analysisTreatment patterns