2023
High-Risk Pulmonary Embolism: Management for the Intensivist
Khosla A, Zhao Y, Mojibian H, Pollak J, Singh I. High-Risk Pulmonary Embolism: Management for the Intensivist. Journal Of Intensive Care Medicine 2023, 38: 1087-1098. PMID: 37455352, DOI: 10.1177/08850666231188290.Peer-Reviewed Original ResearchConceptsHigh-risk pulmonary embolismHigh-risk PE patientsPulmonary embolismRisk stratificationPE patientsTreatment optionsRisk pulmonary embolismMassive pulmonary embolismIntensivist’s perspectiveReperfusion therapySupportive careAcute managementPatientsIntensivistsSupport optionsEmbolismHigh rateCarePhysiological consequencesOutcomesTreatmentOptionsStratificationMorbidityTherapyValidation of the rCAST score and comparison to the PCAC and FOUR scores for prognostication after out-of-hospital cardiac arrest
Kim N, Kitlen E, Garcia G, Khosla A, Miller P, Johnson J, Wira C, Greer D, Gilmore E, Beekman R. Validation of the rCAST score and comparison to the PCAC and FOUR scores for prognostication after out-of-hospital cardiac arrest. Resuscitation 2023, 188: 109832. PMID: 37178901, DOI: 10.1016/j.resuscitation.2023.109832.Peer-Reviewed Original ResearchConceptsPoor neurologic outcomeUnited States cohortHospital cardiac arrestOHCA patientsNeurologic outcomeCardiac arrestPost-cardiac arrest syndromePoor neurological outcomeScore predictive abilityHospital mortalityNeurological outcomeUnResponsiveness (FOUR) scorePoor outcomeRetrospective studyAccurate outcome predictionPrognostic performanceFull OutlineDeLong testOutcome predictionPatientsMortalityOutcomesScoresCohortPredictive ability
2022
Bedside monitoring of hypoxic ischemic brain injury using low-field, portable brain magnetic resonance imaging after cardiac arrest
Beekman R, Crawford A, Mazurek MH, Prabhat AM, Chavva IR, Parasuram N, Kim N, Kim JA, Petersen N, de Havenon A, Khosla A, Honiden S, Miller PE, Wira C, Daley J, Payabvash S, Greer DM, Gilmore EJ, Kimberly W, Sheth KN. Bedside monitoring of hypoxic ischemic brain injury using low-field, portable brain magnetic resonance imaging after cardiac arrest. Resuscitation 2022, 176: 150-158. PMID: 35562094, PMCID: PMC9746653, DOI: 10.1016/j.resuscitation.2022.05.002.Peer-Reviewed Original ResearchConceptsCardiac arrestBrain injuryHypoxic-ischemic brain injuryAdverse neurological outcomesIschemic brain injurySingle-center studyBrain magnetic resonanceBrain injury severityBoard-certified neuroradiologistsLow-field MRIFLAIR signal intensityNeurological outcomeCA patientsIll patientsMRI findingsCA survivorsCenter studyMRI examinationsClinical careHigh riskInjury severityPatientsSignal intensityBedside monitoringMR imaging
2014
Hypoglycemia in the Hospital: Systems-Based Approach to Recognition, Treatment, and Prevention
Varlamov EV, Kulaga ME, Khosla A, Prime DL, Rennert NJ. Hypoglycemia in the Hospital: Systems-Based Approach to Recognition, Treatment, and Prevention. Hospital Practice 2014, 42: 163-172. PMID: 25502140, DOI: 10.3810/hp.2014.10.1153.Peer-Reviewed Original ResearchConceptsInpatient diabetes careImmediate adverse reactionsUnfavorable clinical outcomeAmerican Diabetes AssociationTransitions of careInpatient glycemic controlHealth care costsAdditional hospital resourcesCoordination of nutritionQuality improvement effortsAcute illnessGlycemic controlHospitalized patientsClinical outcomesPredispose patientsDiabetes AssociationHypoglycemic eventsDiabetes careAdverse reactionsEndocrine SocietyInsulin administrationPatient educationHospital resourcesHypoglycemiaHospital routine