2025
“You just want to kill the pain and get numb:” A mixed methods study investigating the lived experiences of individuals experiencing homelessness enrolled in outpatient methadone treatment
Gazzola M, Thompson E, Hoffman K, Saeed G, Baylen C, Madden L, Eggert K, Beitel M, Barry D. “You just want to kill the pain and get numb:” A mixed methods study investigating the lived experiences of individuals experiencing homelessness enrolled in outpatient methadone treatment. Journal Of Substance Use And Addiction Treatment 2025, 172: 209668. PMID: 40057243, DOI: 10.1016/j.josat.2025.209668.Peer-Reviewed Original ResearchOpioid use disorderPersonal barriersThematic analysisRisk of overdoseOpioid treatment programsStructural barriersPublic health priorityMixed methods studyHealth-related vulnerabilityExperience of homelessnessPeriods of homelessnessSemi-structured interviewsExperiences of individualsHealthcare experiencesHealth priorityParticipants' experiencesPrimary themesMethods studyImprove engagementMethadone treatmentDescriptive statisticsTreatment engagementQualitative interviewsExit homelessnessHousing statusRetention and dropout from sublingual and extended-release buprenorphine treatment: A comparative analysis of data from a nationally representative sample of commercially-insured people with opiod use disorder in the United States
Ivasiy R, Madden L, Johnson K, Machavariani E, Ahmad B, Oliveros D, Tan J, Kil N, Altice F. Retention and dropout from sublingual and extended-release buprenorphine treatment: A comparative analysis of data from a nationally representative sample of commercially-insured people with opiod use disorder in the United States. International Journal Of Drug Policy 2025, 138: 104748. PMID: 40020306, PMCID: PMC12045481, DOI: 10.1016/j.drugpo.2025.104748.Peer-Reviewed Original ResearchConceptsOpioid use disorderSL-BUPXR-BUPUse disorderRetrospective cohort studyExtended-release buprenorphineReduce treatment discontinuationDays of supplyTreatment discontinuationSublingual buprenorphineReduce overdose riskBuprenorphine treatmentCohort studyHigh dosesPrimary outcomeImpact of dosagePatientsBuprenorphineMonthsMg/dayCommercially-insured individualsProportion of individualsOpioidOverdose riskImprove health outcomesExploration of the multi-level barriers to scaling up methadone for HIV prevention among people who inject drugs in Kazakhstan
Liberman A, Rozental Y, Ivasiy R, Kussainova A, Primbetova S, Madden L, Terlikbayeva A, Altice F. Exploration of the multi-level barriers to scaling up methadone for HIV prevention among people who inject drugs in Kazakhstan. Journal Of Substance Use And Addiction Treatment 2025, 172: 209640. PMID: 39986387, PMCID: PMC12009200, DOI: 10.1016/j.josat.2025.209640.Peer-Reviewed Original ResearchNominal group techniqueHIV preventionCommunity health workersMulti-level barriersIn-depth interviewsHealth workersPWID clientsSocioecological modelCommunity stakeholdersOpioid use disorderFocus groupsHIV epidemicClinical directorsClinical sitesEducating clientsOpioid agonist therapyImprove implementationGroup techniqueResearch teamCHWsPolicy levelUse disorderCliniciansAlternative medicationsEligibilityAssessing the comparative effectiveness of ECHO and coaching implementation strategies in a jail/provider MOUD implementation trial
Molfenter T, Vechinski J, Kim J, Zhang J, Meng L, Tveit J, Madden L, Taxman F. Assessing the comparative effectiveness of ECHO and coaching implementation strategies in a jail/provider MOUD implementation trial. Implementation Science 2025, 20: 7. PMID: 39901259, PMCID: PMC11792685, DOI: 10.1186/s13012-025-01419-6.Peer-Reviewed Original ResearchConceptsOpioid use disorderIntervention phaseMOUD useJail settingInjectable naltrexoneUse disorderImplementation strategiesCommunity Healthcare OutcomesCommunity-based partnersEffective implementation strategiesPatient countsPublic health opportunityPrevalence of opioid use disorderCommunity-based treatment providersTelementoring modelECHO sessionsTrial registry recordHealthcare outcomesImplementation trialPersistent treatment gapTreatment providersRegistry recordsHealth opportunitiesTreatment gapStudy armsS114 Patient Perspectives on an Open Access Model for Methadone Treatment
Madden L, Hoffman K, Farnum S, Cannata E, Eggert K, DiMeola K, Hermes G, Markaj E, Barry D. S114 Patient Perspectives on an Open Access Model for Methadone Treatment. Drug And Alcohol Dependence 2025, 267: 111534. DOI: 10.1016/j.drugalcdep.2024.111534.Peer-Reviewed Original ResearchW67 Bridging the Regulatory gap: Identifying Opportunities to Enhance Buprenorphine Access in West Virginia’s Opioid Crisis Response
Feinberg J, Bernadine K, Altice F, Hutter-Thomas S, Workman J, Robert L, Madden L. W67 Bridging the Regulatory gap: Identifying Opportunities to Enhance Buprenorphine Access in West Virginia’s Opioid Crisis Response. Drug And Alcohol Dependence 2025, 267: 112009. DOI: 10.1016/j.drugalcdep.2024.112009.Peer-Reviewed Original ResearchW59 Understanding Homelessness Experiences and Social Determinants of Health Among People Experiencing Homelessness Enrolled in Methadone Treatment
Gazzola M, Baylen C, Saeed G, Hoffman K, Thompson E, Madden L, Eggert K, Beitel M, Barry D. W59 Understanding Homelessness Experiences and Social Determinants of Health Among People Experiencing Homelessness Enrolled in Methadone Treatment. Drug And Alcohol Dependence 2025, 267: 112001. DOI: 10.1016/j.drugalcdep.2024.112001.Peer-Reviewed Original ResearchW70 A Pilot Study Examining the Feasibility of a Virtual Reality Pain Management Intervention Groups in Methadone Maintenance Treatment
DiMeola K, Cutter C, Haynes J, Hieftje K, Beitel M, Rossi R, Madden L, Barry D. W70 A Pilot Study Examining the Feasibility of a Virtual Reality Pain Management Intervention Groups in Methadone Maintenance Treatment. Drug And Alcohol Dependence 2025, 267: 112012. DOI: 10.1016/j.drugalcdep.2024.112012.Peer-Reviewed Original ResearchM118 Counselor Terminological Preferences for Common Treatment Experiences Among Patients Receiving Methadone Treatment
Eggert K, Walker K, Beitel M, Cammack K, Rossi R, Gazzola M, Hsaio C, Roehrich T, Madden L, Barry D. M118 Counselor Terminological Preferences for Common Treatment Experiences Among Patients Receiving Methadone Treatment. Drug And Alcohol Dependence 2025, 267: 111712. DOI: 10.1016/j.drugalcdep.2024.111712.Peer-Reviewed Original ResearchT99 Seeking Treatment while Unhoused: A Qualitative Study Investigating the Experiences of People Experiencing Homelessness Enrolled in Outpatient Methadone Treatment
Thompson E, Gazzola M, Hoffman K, Saeed G, Baylen C, Madden L, Eggert K, Beitel M, Barry D. T99 Seeking Treatment while Unhoused: A Qualitative Study Investigating the Experiences of People Experiencing Homelessness Enrolled in Outpatient Methadone Treatment. Drug And Alcohol Dependence 2025, 267: 111867. DOI: 10.1016/j.drugalcdep.2024.111867.Peer-Reviewed Original Research
2024
Corrigendum to: Clinical characteristics associated with problematic pornography use among individuals seeking treatment for opioid use disorder
Stefanovics E, Kraus S, Madden L, Farnum S, Cannata E, Potenza M, Barry D. Corrigendum to: Clinical characteristics associated with problematic pornography use among individuals seeking treatment for opioid use disorder. Journal Of Behavioral Addictions 2024, 13: 947-948. PMID: 39714469, PMCID: PMC11737413, DOI: 10.1556/2006.2024.40000.Peer-Reviewed Original ResearchDecrease in provider stigma is associated with improved quality health indicators among individuals receiving methadone in primary care centers in Ukraine
Machavariani E, Bromberg D, Dumchev K, Esserman D, Earnshaw V, Pykalo I, Filippovich M, Ivasiy R, Ahmad B, Long J, Haddad M, Madden L, Oliveros D, Dvoriak S, Altice F. Decrease in provider stigma is associated with improved quality health indicators among individuals receiving methadone in primary care centers in Ukraine. International Journal Of Drug Policy 2024, 136: 104682. PMID: 39705875, PMCID: PMC11821433, DOI: 10.1016/j.drugpo.2024.104682.Peer-Reviewed Original ResearchConceptsPrimary care centersQuality health indicatorsProvider stigmaEvidence-based practiceGuideline-concordantPatient outcomesHealth indicatorsReduce provider stigmaCare centerInfluence healthcare utilizationSpecialty health servicesPatient-level outcomesTele-educationImprove patient outcomesProvider fearsImplementation trialHealthcare utilizationPreventive careHealth servicesPoor healthLinear mixed-effects modelsImprove attitudesStigmaIncrease accessMixed-effects modelsDisruptions to HIV Prevention During Armed Conflict in Ukraine and Other Settings
Nikitin B, Bromberg D, Ivasiy R, Madden L, Machavariani E, Dvoriak S, Poole D, Otiashvilli D, Altice F. Disruptions to HIV Prevention During Armed Conflict in Ukraine and Other Settings. Current HIV/AIDS Reports 2024, 22: 10. PMID: 39672977, PMCID: PMC11823171, DOI: 10.1007/s11904-024-00716-x.Peer-Reviewed Original ResearchTransformation of the HIV treatment cascade for people who inject drugs in Ukraine
Bromberg D, Rhoades D, Madden L, Ivasiy R, Meteliuk A, Pykalo I, Filippovych M, Nikitin B, Farnum S, Fomenko T, Dvoriak S, Altice F. Transformation of the HIV treatment cascade for people who inject drugs in Ukraine. AIDS 2024, 39: 306-311. PMID: 39589135, DOI: 10.1097/qad.0000000000004056.Peer-Reviewed Original ResearchOpioid agonist therapyAntiretroviral therapyImprove HIV treatment outcomesHIV treatment outcomesHIV care cascadeCross-sectional biobehavioral surveyTreatment outcomesCare cascadeUkraine's HIV epidemicPrescription of antiretroviral therapyPrescribed antiretroviral therapyAdherence to antiretroviral therapyHIV treatment cascadeAgonist therapyBiobehavioral surveyOpioid dependenceHIV diagnosisTreatment cascadeHIV epidemicHIVOpioidPWIDTherapyDrugOutcomesStrategies to Deimplement Opioid Prescribing in Primary Care
Quanbeck A, Robinson J, Jacobson N, Li X, Hennessy-Garza R, Landeck J, Cohen A, Madden L, Pulvermacher A, Brown R. Strategies to Deimplement Opioid Prescribing in Primary Care. JAMA Network Open 2024, 7: e2438325. PMID: 39388183, PMCID: PMC11581553, DOI: 10.1001/jamanetworkopen.2024.38325.Peer-Reviewed Original ResearchConceptsCluster randomized clinical trialDeimplementation strategiesMorphine milligram equivalent doseMorphine milligram equivalentsPractice facilitationOpioid prescribingIncreased screeningTreatment agreementsUS health care systemCenters for Disease Control and Prevention guidelinesRandomized clinical trialsUrine drug screensPrimary care clinicsPrimary care settingPrimary outcomeMental health screeningPain-related interferenceHealth care systemHigh-intensity groupEnjoyment of lifeChronic pain managementPrimary careCare clinicsCare settingsHealth screeningTrajectory and progress of opioid agonist therapy programs in the Kyrgyz Republic
Liberman A, Kurmanalieva A, Biibosunova D, Shumskaya N, Ivasiy R, Bromberg D, Madden L, Altice F. Trajectory and progress of opioid agonist therapy programs in the Kyrgyz Republic. Global Health Economics And Sustainability 2024, 2: 2536. PMID: 40212662, DOI: 10.36922/ghes.2536.Peer-Reviewed Original ResearchOpioid agonist therapyHuman immunodeficiency virusMortality of human immunodeficiency virusOpioid agonist therapy programsOpioid use disorderMethadone programsHIV prevention strategiesAgonist therapyImmunodeficiency virusClinical protocolsEffective treatmentUse disorderNeighboring countriesHIV preventionKyrgyz RepublicMethadoneOpioidCentral AsiaIncreased state supportCentral Asian countriesDrugCarceral systemInternational donorsLocal news coveragePolitical challengesClinical characteristics associated with problematic pornography use among individuals seeking treatment for opioid use disorder
Stefanovics E, Kraus S, Madden L, Farnum S, Cannata E, Potenza M, Barry D. Clinical characteristics associated with problematic pornography use among individuals seeking treatment for opioid use disorder. Journal Of Behavioral Addictions 2024, 13: 938-946. PMID: 39298267, PMCID: PMC11737410, DOI: 10.1556/2006.2024.00037.Peer-Reviewed Original ResearchBrief Pornography ScreenOpioid use disorderPornography useOpioid use disorder treatmentUse disorderMeasures of substance useMeasures of impulsivityProblematic pornography useMinority of individualsNegative urgencyPositive urgencyPsychotic symptomsSelf-reported dataBehavioral addictionsGambling disorderPsychiatric disordersPsychiatric symptomsSensation-seekingEmotional labilitySelf-harmSubstance useDisordersOpioidIndividualsSymptomsDesign and implementation of a Type-2 hybrid, prospective randomized trial of opioid agonist therapies integration into primary care clinics in Ukraine
Machavariani E, Dumchev K, Pykalo I, Filippovych M, Ivasiy R, Esserman D, Madden L, Bromberg D, Haddad M, Morozova O, Ahmad B, Gómez D, Farnum S, Dvoriak S, Altice F. Design and implementation of a Type-2 hybrid, prospective randomized trial of opioid agonist therapies integration into primary care clinics in Ukraine. Contemporary Clinical Trials 2024, 146: 107690. PMID: 39265780, PMCID: PMC11531372, DOI: 10.1016/j.cct.2024.107690.Peer-Reviewed Original ResearchPrimary care centersQuality health indicatorsNon-communicable diseasesSpecialty treatment centersOpioid agonist therapyImplementation of integrated carePay-for-performance incentivesPrimary care clinicsPrimary care settingSelf-reported prevalencePay-for-performancePrevalence of medical comorbiditiesParticipants self-reportedEffective evidence-based treatmentsHealth of PWIDEvidence-based treatmentsIntegrated careCare clinicsImplementation outcomesImplementation trialCare settingsElectronic chart reviewHigh-burden countriesSpecialty servicesHIV prevalenceThe cascade of care for commercially-insured persons with opioid use disorder and comorbid HIV and HCV infections
Ivasiy R, Madden L, DiDomizio E, Johnson K, Machavariani E, Ahmad B, Oliveros D, Ram A, Kil N, Altice F. The cascade of care for commercially-insured persons with opioid use disorder and comorbid HIV and HCV infections. Drug And Alcohol Dependence 2024, 263: 112410. PMID: 39159600, PMCID: PMC12045330, DOI: 10.1016/j.drugalcdep.2024.112410.Peer-Reviewed Original ResearchOpioid use disorderXR-NTXUse disorderHCV infectionPrescribed MOUDOpioid use disorder cascadePrevalence of opioid use disorderRetrospective cohort studyHigher treatment retentionCascade of careConcurrent infectious diseasesSix-month retentionHCV/HIV coinfectionComorbid HIVCohort studyHospital-based settingPrescribed methadoneHCVMOUD initiationHIVHCV epidemicOpioidMethadoneMOUD prescriptionsTreatment retentionW96 Scaling up Opioid Agonist Therapies in Ukraine Before the War: Implementation Factors Related to Disruptions From Legislative Reform and COVID-19
Madden L, Ivasiy R, Polonsky M, Farnum S, Galvez S, Meteliuk A, Bromberg D, Altice F. W96 Scaling up Opioid Agonist Therapies in Ukraine Before the War: Implementation Factors Related to Disruptions From Legislative Reform and COVID-19. Drug And Alcohol Dependence 2024, 260: 110714. DOI: 10.1016/j.drugalcdep.2023.110714.Peer-Reviewed Original Research
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