2025
Receipt of addiction treatment after nonfatal opioid overdose and risk of subsequent overdose: A retrospective cohort study
Howell B, Black A, Lin H, Liberatore M, Greene C, D'Onofrio G, Heimer R, Grau L, Hawk K, Fiellin D, Becker W. Receipt of addiction treatment after nonfatal opioid overdose and risk of subsequent overdose: A retrospective cohort study. Drug And Alcohol Dependence 2025, 273: 112679. PMID: 40413965, PMCID: PMC12178112, DOI: 10.1016/j.drugalcdep.2025.112679.Peer-Reviewed Original ResearchConceptsAddiction treatment modalitiesAddiction treatmentInpatient addiction treatmentOpioid overdose survivorsOverdose survivorsOpioid agonist treatmentOpioid overdoseReceipt of methadoneOpioid withdrawalInpatient treatmentBenzodiazepine exposureNon-medicalAddictionAssociated with reduced riskNonfatal opioid overdoseAgonist treatmentNon-fatal opioid overdoseTreatment modalitiesAssociated with increased riskBenzodiazepinesIndividual level dataMethadoneRetrospective cohort studyOpioidBuprenorphine
2021
Emergency Department Treatment of Opioid Use Disorder
Samuels E, Coupet E, D’Onofrio G. Emergency Department Treatment of Opioid Use Disorder. 2021, 57-75. DOI: 10.1007/978-3-030-80818-1_5.ChaptersOpioid use disorderED visitsUse disordersUntreated opioid use disorderDrug-related emergency department visitsNonfatal opioid overdoseUS ED visitsEmergency department treatmentFirst-line treatmentLow-dose ketamineEmergency department visitsIllicit opioid useDosage of medicationRegional nerve blocksAddiction treatment medicationsHarm reduction servicesTake-home naloxoneCost-effective treatmentAcute painOpioid useDepartment visitsOUD treatmentTreatment medicationsNerve blockOpioid agonistsEmergency Department Visits for Nonfatal Opioid Overdose During the COVID-19 Pandemic Across Six US Health Care Systems
Soares WE, Melnick ER, Nath B, D'Onofrio G, Paek H, Skains RM, Walter LA, Casey MF, Napoli A, Hoppe JA, Jeffery MM. Emergency Department Visits for Nonfatal Opioid Overdose During the COVID-19 Pandemic Across Six US Health Care Systems. Annals Of Emergency Medicine 2021, 79: 158-167. PMID: 34119326, PMCID: PMC8449788, DOI: 10.1016/j.annemergmed.2021.03.013.Peer-Reviewed Original ResearchConceptsHealth care systemCause ED visitsNonfatal opioid overdoseED visitsOpioid use disorderCare systemOpioid overdoseUse disordersCOVID-19 pandemicOpioid-related complicationsEmergency department visitsHospital-based interventionsED visit ratesEmergency department utilizationVisit countsUS health care systemOpioid overdose ratesDepartment visitsHistorical controlsAdult visitsOpioid overdosesOverdose ratesMedical emergencyVisit ratesMore weeks
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