2017
Ranolazine and Microvascular Angina by PET in the Emergency Department: Results From a Pilot Randomized Controlled Trial
Safdar B, D’Onofrio G, Dziura J, Russell RR, Johnson C, Sinusas AJ. Ranolazine and Microvascular Angina by PET in the Emergency Department: Results From a Pilot Randomized Controlled Trial. Clinical Therapeutics 2017, 39: 55-63. PMID: 28081848, PMCID: PMC10345862, DOI: 10.1016/j.clinthera.2016.12.002.Peer-Reviewed Original ResearchConceptsCoronary microvascular dysfunctionCoronary flow reserveCoronary artery diseaseChest painSymptomatic patientsArtery diseasePrimary outcomeEmergency departmentNonobstructive coronary artery diseaseRb-82 positron emission tomographyEffect of ranolazineRate-pressure productEmergency department patientsQTc-prolonging drugsRobust clinical trialsPositron emission tomographyHypertensive urgencyMicrovascular anginaMicrovascular dysfunctionUnderdiagnosed causeControlled TrialsDepartment patientsHeart failureAcute symptomsPressure product
2006
Intravenous Morphine Plus Ketorolac Is Superior to Either Drug Alone for Treatment of Acute Renal Colic
Safdar B, Degutis LC, Landry K, Vedere SR, Moscovitz HC, D’Onofrio G. Intravenous Morphine Plus Ketorolac Is Superior to Either Drug Alone for Treatment of Acute Renal Colic. Annals Of Emergency Medicine 2006, 48: 173-181.e1. PMID: 16953530, DOI: 10.1016/j.annemergmed.2006.03.013.Peer-Reviewed Original ResearchConceptsAcute renal colicRenal colicRescue analgesiaMorphine groupCombination of morphineHours of presentationVerbal pain scalePresence of peritonitisVisual analog scaleAnti-inflammatory drugsIntravenous ketorolacKetorolac groupRescue morphineIntravenous morphinePain reductionPain reliefPain scoresModerate painPain scaleConsecutive patientsPrimary outcomeAnalog scaleCombination therapyEmergency departmentPain ratings