2023
Early emergency department experience with 7‐day extended‐release injectable buprenorphine for opioid use disorder
D'Onofrio G, Perrone J, Hawk K, Cowan E, McCormack R, Coupet E, Owens P, Martel S, Huntley K, Walsh S, Lofwall M, Herring A, Investigators T. Early emergency department experience with 7‐day extended‐release injectable buprenorphine for opioid use disorder. Academic Emergency Medicine 2023, 30: 1264-1271. PMID: 37501652, PMCID: PMC10822018, DOI: 10.1111/acem.14782.Peer-Reviewed Original ResearchConceptsOpioid use disorderEmergency departmentUse disordersSevere opioid use disorderOngoing clinical trialsEuropean Medicines AgencyEmergency department experienceInjectable buprenorphineClinician barriersED patientsED settingEmergency cliniciansInsurance statusClinical trialsReferral sitesDrug AdministrationMedicines AgencyBuprenorphine preparationsMedicationsU.S. FoodTreatment innovationsBuprenorphineDepartment's experienceEarly experienceDisordersImplementing Programs to Initiate Buprenorphine for Opioid Use Disorder Treatment in High-Need, Low-Resource Emergency Departments: A Nonrandomized Controlled Trial
McCormack R, Rotrosen J, Gauthier P, D'Onofrio G, Fiellin D, Marsch L, Novo P, Liu D, Edelman E, Farkas S, Matthews A, Mulatya C, Salazar D, Wolff J, Knight R, Goodman W, Williams J, Hawk K. Implementing Programs to Initiate Buprenorphine for Opioid Use Disorder Treatment in High-Need, Low-Resource Emergency Departments: A Nonrandomized Controlled Trial. Annals Of Emergency Medicine 2023, 82: 272-287. PMID: 37140493, PMCID: PMC10524047, DOI: 10.1016/j.annemergmed.2023.02.013.Peer-Reviewed Original ResearchConceptsBuprenorphine programImplementation facilitationEmergency departmentMedical recordsOpioid use disorder treatmentMain secondary outcomesMore treatment visitsPrimary implementation outcomeNonrandomized Controlled TrialPatient-level outcomesPatients' medical recordsUse disorder treatmentTreatment 30 daysBuprenorphine administrationOpioid useSecondary outcomesControlled TrialsTreatment visitsED settingUnique patientsClinicians' readinessEligibility criteriaClinical protocolsDisorder treatmentOverdose events
2021
Implementation facilitation to introduce and support emergency department-initiated buprenorphine for opioid use disorder in high need, low resource settings: protocol for multi-site implementation-feasibility study
McCormack RP, Rotrosen J, Gauthier P, D’Onofrio G, Fiellin DA, Marsch LA, Novo P, Liu D, Edelman EJ, Farkas S, Matthews AG, Mulatya C, Salazar D, Wolff J, Knight R, Goodman W, Hawk K. Implementation facilitation to introduce and support emergency department-initiated buprenorphine for opioid use disorder in high need, low resource settings: protocol for multi-site implementation-feasibility study. Addiction Science & Clinical Practice 2021, 16: 16. PMID: 33750454, PMCID: PMC7941881, DOI: 10.1186/s13722-021-00224-y.Peer-Reviewed Original ResearchConceptsEmergency departmentLow-resource settingsImplementation facilitationUse disordersEmergency department-initiated buprenorphineResource settingsImplementation-effectiveness studyTreatment of OUDOpioid use disorderNon-emergent conditionsSubstance use disordersImplementation feasibility studyOUD interventionsED settingMedical recordsBuprenorphineClinical protocolsHigh needReferral programDisorder screeningDiscussionThis studyImplementation studyAdministrative dataReferralTreatment
2012
A Brief Intervention Reduces Hazardous and Harmful Drinking in Emergency Department Patients
D'Onofrio G, Fiellin DA, Pantalon MV, Chawarski MC, Owens PH, Degutis LC, Busch SH, Bernstein SL, O'Connor PG. A Brief Intervention Reduces Hazardous and Harmful Drinking in Emergency Department Patients. Annals Of Emergency Medicine 2012, 60: 181-192. PMID: 22459448, PMCID: PMC3811141, DOI: 10.1016/j.annemergmed.2012.02.006.Peer-Reviewed Original ResearchConceptsBrief Negotiation InterviewStandard careEmergency department patientsBrief interventionAlcohol consumptionDepartment patientsHarmful drinkersDrinking outcomesHarmful drinkingAssessment groupStandard care groupAdult ED patientsNegative health behaviorsSecondary outcomesPrimary outcomeED patientsCare groupED settingTelephone boosterBooster groupBinge episodesHealth behaviorsPatientsAlcohol useCare
2009
Alcohol, Tobacco, and Other Drugs: Future Directions for Screening and Intervention in the Emergency Department
Cunningham RM, Bernstein SL, Walton M, Broderick K, Vaca FE, Woolard R, Bernstein E, Blow F, D’Onofrio G. Alcohol, Tobacco, and Other Drugs: Future Directions for Screening and Intervention in the Emergency Department. Academic Emergency Medicine 2009, 16: 1078-1088. PMID: 20053226, DOI: 10.1111/j.1553-2712.2009.00552.x.Peer-Reviewed Original ResearchConceptsEmergency departmentBrief interventionED patientsSubstance useLarge public health impactEffectiveness of screeningMultiple risk behaviorsAvailable community servicesMental health treatmentPublic health impactOptimal delivery methodEffective brief interventionsPractical screening instrumentAcademic Emergency Medicine consensus conferenceMedical care systemCost-effectiveness researchED settingPatient subgroupsInterventional studyTreatment referralPreventive servicesEffectiveness trialReferral strategiesTobacco useInjury prevention
2007
Public health considerations in knowledge translation in the emergency department.
Bernstein S, Bernstein E, Boudreaux E, Babcock-Irvin C, Mello M, Kapur A, Becker B, Sattin R, Cohen V, D'Onofrio G. Public health considerations in knowledge translation in the emergency department. Academic Emergency Medicine 2007, 14: 1036-41. PMID: 17699805, DOI: 10.1197/j.aem.2007.06.012.Peer-Reviewed Original ResearchConceptsPublic health interventionsEmergency departmentHealth interventionsLack of efficacyPublic health initiativesKnowledge translationPublic health expertsPublic health considerationsED settingPreventive careCurrent evidenceConsensus conferenceClinical information systemsED personnelEffective preventivePreventive interventionsHealth initiativesMedical careEvidence uptakeVulnerable populationsHealth expertsUnique populationEmergency medicineInterventionHealth considerations
1998
Patients with Alcohol Problems in the Emergency Department, Part 1: Improving Detection*
D'Onofrio G, Bernstein E, Bernstein J, Woolard R, Brewer P, Craig S, Zink B, Force F. Patients with Alcohol Problems in the Emergency Department, Part 1: Improving Detection*. Academic Emergency Medicine 1998, 5: 1200-1209. PMID: 9864134, DOI: 10.1111/j.1553-2712.1998.tb02696.x.Peer-Reviewed Original ResearchConceptsAlcohol problemsEmergency medicine practiceBusy ED settingBrief screening toolSubsequent morbidityED patientsAcute complaintsED settingEmergency departmentPatient populationEarly interventionMedicine practicePatientsScreening toolAlcohol useDependent drinkersEarly detectionTask ForceMorbidityMortalityComplaintsDrinkers