2021
The shifting age distribution of people with HIV using antiretroviral therapy in the United States
Althoff KN, Stewart CN, Humes E, Zhang J, Gerace L, Boyd CM, Wong C, Justice AC, Gebo KA, Thorne JE, Rubtsova AA, Horberg MA, Silverberg MJ, Leng SX, Rebeiro PF, Moore RD, Buchacz K, Kasaie P. The shifting age distribution of people with HIV using antiretroviral therapy in the United States. AIDS 2021, 36: 459-471. PMID: 34750289, PMCID: PMC8795488, DOI: 10.1097/qad.0000000000003128.Peer-Reviewed Original ResearchMeSH KeywordsAdultAge DistributionAgedCohort StudiesEpidemicsHIV InfectionsHumansMiddle AgedRisk FactorsUnited StatesConceptsAntiretroviral therapyRace/ethnicityNorth American AIDS Cohort CollaborationHIV acquisition riskHIV Epidemic goalsOverall median ageSubgroups of sexRelative reductionAge distributionCohort CollaborationHIV diagnosisMedian ageRisk groupsUS CentersAcquisition riskHIVUS populationDisease controlSurveillance reports
2015
Cumulative Incidence of Cancer Among Persons With HIV in North America: A Cohort Study.
Silverberg MJ, Lau B, Achenbach CJ, Jing Y, Althoff KN, D'Souza G, Engels EA, Hessol NA, Brooks JT, Burchell AN, Gill MJ, Goedert JJ, Hogg R, Horberg MA, Kirk GD, Kitahata MM, Korthuis PT, Mathews WC, Mayor A, Modur SP, Napravnik S, Novak RM, Patel P, Rachlis AR, Sterling TR, Willig JH, Justice AC, Moore RD, Dubrow R. Cumulative Incidence of Cancer Among Persons With HIV in North America: A Cohort Study. Annals Of Internal Medicine 2015, 163: 507-18. PMID: 26436616, PMCID: PMC4711936, DOI: 10.7326/m14-2768.Peer-Reviewed Original ResearchConceptsAge 75 yearsNon-Hodgkin lymphomaCumulative cancer incidenceCumulative incidenceLung cancerKaposi's sarcomaCalendar trendsCohort studyHIV statusHodgkin's lymphomaCancer incidenceLiver cancerNorth American AIDS Cohort CollaborationOral cavity/pharyngeal cancerHigher cumulative incidenceMortality rate trendsCohort CollaborationAnal cancerAntiretroviral therapyPharyngeal cancerSmoking cessationColorectal cancerLifetime riskIncidence trendsUninfected adultsFood Insecurity and Health: Data from the Veterans Aging Cohort Study
Wang EA, McGinnis KA, Goulet J, Bryant K, Gibert C, Leaf DA, Mattocks K, Fiellin LE, Vogenthaler N, Justice AC, Fiellin DA. Food Insecurity and Health: Data from the Veterans Aging Cohort Study. Public Health Reports 2015, 130: 261-268. PMID: 25931630, PMCID: PMC4388224, DOI: 10.1177/003335491513000313.Peer-Reviewed Original ResearchConceptsVeterans Aging Cohort StudyVeterans Health AdministrationAging Cohort StudyCohort studyWorse controlMedical conditionsControl of hypertensionIndependent risk factorMultivariable logistic regressionTest of trendFood insecureFood insecurityRisk factorsHealth AdministrationPast monthLogistic regressionRecent homelessnessHealth careHypertensionVeteransHIVDepressionAfrican AmericansMarijuana usePrevalence
2014
HIV Infection and Cardiovascular Disease in Women
Womack JA, Chang C, So‐Armah K, Alcorn C, Baker JV, Brown ST, Budoff M, Butt AA, Gibert C, Goetz MB, Gottdiener J, Gottlieb S, Justice AC, Leaf D, McGinnis K, Rimland D, Rodriguez‐Barradas M, Sico J, Skanderson M, Tindle H, Tracy RP, Warner A, Freiberg MS. HIV Infection and Cardiovascular Disease in Women. Journal Of The American Heart Association 2014, 3: e001035. PMID: 25324353, PMCID: PMC4323817, DOI: 10.1161/jaha.114.001035.Peer-Reviewed Original ResearchMeSH KeywordsAdultAge DistributionAgedCardiovascular DiseasesCase-Control StudiesComorbidityConfidence IntervalsFemaleHIV InfectionsHumansLongitudinal StudiesMiddle AgedPrevalenceProportional Hazards ModelsProspective StudiesRisk AssessmentSeverity of Illness IndexSurvival AnalysisUnited StatesUser-Computer InterfaceVeteransConceptsRisk of CVDCVD eventsCardiovascular diseaseHIV infectionVeterans Aging Cohort StudyCox proportional hazards modelHIV uninfected womenIncident CVD eventsIncident cardiovascular diseaseIndependent risk factorAging Cohort StudyClinical Modification codesFirst clinical encounterDeath certificate dataProportional hazards modelSubstance use/abuseUse/abuseRace/ethnicityUninfected womenHepatitis CHIV- womenLast followCohort studyIschemic strokeUnstable angina
2010
Virologic and immunologic response to HAART, by age and regimen class
Althoff KN, Justice AC, Gange SJ, Deeks SG, Saag MS, Silverberg MJ, Gill MJ, Lau B, Napravnik S, Tedaldi E, Klein MB, Gebo KA. Virologic and immunologic response to HAART, by age and regimen class. AIDS 2010, 24: 2469-2479. PMID: 20829678, PMCID: PMC3136814, DOI: 10.1097/qad.0b013e32833e6d14.Peer-Reviewed Original ResearchConceptsCD4 cell countImmunologic responseNorth American AIDS Cohort CollaborationCell countMean CD4 cell countProtease inhibitor-based regimenNonnucleoside reverse transcriptase inhibitorAntiretroviral-naive adultsInhibitor-based regimenInitial antiretroviral regimenProspective cohort studyConfidence intervalsReverse transcriptase inhibitorImpact of ageInverse probability weightsCohort CollaborationInitial regimenAntiretroviral regimenVirologic responseCohort studyViral loadEligible participantsOdds ratioTranscriptase inhibitorRegimen
2008
Workshop on HIV Infection and Aging: What Is Known and Future Research Directions
High K, Effros R, Fletcher C, Gebo K, Halter J, Hazzard W, Horne F, Huebner R, Janoff E, Justice A, Kuritzkes D, Nayfield S, Plaeger S, Schmader K, Ashworth J, Campanelli C, Clayton C, Rada B, Woolard N, High K. Workshop on HIV Infection and Aging: What Is Known and Future Research Directions. Clinical Infectious Diseases 2008, 47: 542-553. PMID: 18627268, PMCID: PMC3130308, DOI: 10.1086/590150.Peer-Reviewed Original ResearchConceptsHIV infectionHuman immunodeficiency virus (HIV) infectionInfectious diseasesImmunodeficiency virus infectionInfectious Diseases SocietyActive antiretroviral treatmentNational InstituteDiseases SocietyAntiretroviral treatmentImmunodeficiency syndromeAdvanced ageChronic diseasesVirus infectionDrug toxicityInfectionSpecialty ProfessorsLife expectancyDiseaseComorbiditiesMedical AssociationHigh-priority topicsTreatmentAssociationAging processPriority topics
2007
Prognosis of HIV-1-infected patients up to 5 years after initiation of HAART: collaborative analysis of prospective studies
May M, Sterne JA, Sabin C, Costagliola D, Justice AC, Thiébaut R, Gill J, Phillips A, Reiss P, Hogg R, Ledergerber B, D'Arminio Monforte A, Schmeisser N, Staszewski S, Egger M. Prognosis of HIV-1-infected patients up to 5 years after initiation of HAART: collaborative analysis of prospective studies. AIDS 2007, 21: 1185-1197. PMID: 17502729, PMCID: PMC3460385, DOI: 10.1097/qad.0b013e328133f285.Peer-Reviewed Original ResearchConceptsStart of HAARTCD4 cell countCell countHIV-1 RNA levelsHIV-1-infected patientsInitiation of HAARTTreatment-naive patientsDiagnosis of AIDSInjection drug useVirological responseHIV careNew AIDSCumulative incidenceParametric survival modelsClinical stageProspective studyRisk calculatorHAARTProgression rateTreatment changesPatientsDrug usePrognostic modelAIDSCells/
2006
Association of Comorbidity with Physical Disability in Older HIV-Infected Adults
Oursler KK, Goulet JL, Leaf DA, Akingicil A, Katzel LI, Justice A, Crystal S. Association of Comorbidity with Physical Disability in Older HIV-Infected Adults. AIDS Patient Care And STDs 2006, 20: 782-791. PMID: 17134352, DOI: 10.1089/apc.2006.20.782.Peer-Reviewed Original ResearchMeSH KeywordsAdultAge DistributionAgingChronic DiseaseComorbidityDisabled PersonsFemaleHIV InfectionsHumansMaleMiddle AgedUnited StatesVeteransConceptsHIV-negative patientsPhysical functioningComorbid conditionsVeterans Aging Cohort StudyGeneral medical comorbidityHIV medical careHIV-negative veteransRelationship of comorbiditiesHIV disease stageHIV-negative subjectsAssociation of comorbiditiesChronic lung diseaseAging Cohort StudyCoronary artery diseaseYears of ageSelf-reported difficultyOlder HIVAntiretroviral therapyMedical comorbiditiesCohort studyArtery diseaseClinical factorsPatient groupDisease stageLung disease
2004
Psychiatric and neurocognitive disorders among HIV-positive and negative veterans in care
Justice AC, McGinnis KA, Atkinson JH, Heaton RK, Young C, Sadek J, Madenwald T, Becker JT, Conigliaro J, Brown ST, Rimland D, Crystal S, Simberkoff M. Psychiatric and neurocognitive disorders among HIV-positive and negative veterans in care. AIDS 2004, 18: 49-59. PMID: 15075498, DOI: 10.1097/00002030-200401001-00008.Peer-Reviewed Original ResearchConceptsHIV-negative subjectsHIV-positive subjectsNeurocognitive disordersDepressive symptomsAlcohol abuseDrug abuseHIV-negative veteransVeterans Aging CohortGeneral medicine clinicHIV-positive veteransSymptoms of depressionMemory problemsConvenience subsetOlder HIVHIV infectionMedicine clinicPsychiatric testingHigh prevalencePatient reportsSubstantial prevalenceGreater prevalenceAvailable measuresAging CohortNeurocognitive problemsInfectious diseases