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Sonia Caprio, MD

Professor of Pediatrics (Endocrinology)

Contact Information

Sonia Caprio, MD

Patient Care Location

Mailing Address

  • Pediatric Endocrinology & Diabetes

    PO Box 208064

    New Haven, CT 06520-8064

    United States



I have been involved in Patient-Oriented Research in the field of Childhood Obesity and Type 2 diabetes (T2D) in youth for the past 25 years. Realizing the need to understand the pathophysiology and to find better treatments for T2D in Obese Youth, I have been investigating the role of insulin resistance and beta-cell dysfunction at the earliest stage of T2D, namely Impaired Glucose Tolerance (IGT). My research in pre-diabetes in obese children and adolescents has brought into focus at the national level the magnitude of the obesity problem in children in the US. This research demonstrated a much faster tempo of progression of beta-cell failure in obese adolescents, which helped to stimulate the funding of two NIDDK RCTs in obese youth; The TODAY and RISE studies. In recognition of the importance of this work, in 2008 Dr. Caprio was awarded the prestigious “Distinguished Clinical Scientist Award (DCSA)” from the American Diabetes Association. Her research spans both clinical and basic research in metabolism, genetics, and imaging and is the recipient of the “Distinguished Leader in Insulin Resistance” 2015 Award from the International Committee for Insulin Resistance (ICIR). Over the past decade, our group has assembled two large multiethnic cohorts of children/adolescents cohorts: The Pathogenesis of Youth Onset Diabetes (PYOD) study (NCT01967849), (R01HD040787, R01DK111038), and The Yale Pediatric NAFLD/NASH Cohort (NCT01966627), which served as the vehicle for a series of studies aimed at investigating the roles of insulin resistance, beta-cell dysfunction and NAFLD in the earliest stage of T2D: Impaired Glucose Tolerance (IGT).

Education & Training

  • Fellow
    Yale University School of Medicine (1989)
  • Resident
    Temple University Hospital (1983)
  • Resident
    Ospedale Cardarelli (1980)
  • Resident
    Universita' di Medicina e Chirurgia (1980)
  • MD
    Universita di Medicina e Chirurgia (1978)

Honors & Recognition

AwardAwarding OrganizationDate
2015 Distinguished Leader in Insulin Resistance Award, International Committee for Insulin Resistance (ICIR)2020
2017 The Samuel J. Fomon Nutrition Award from the American Academy of Pediatrics2020
2001-2011 K24 Investigator Award in Patient Oriented ResearchNIH-NICD2020
2003 Bayer Scholar Award in Diabetes Research2020
2008-2012 Distinguished Clinical Scientist Award, American Diabetes AssociationAmerican Diabetes Association2020

Departments & Organizations