1990
Reduction of myocardial ischemia during percutaneous transluminal coronary angioplasty with oxygenated Fluosol®11Fluosol® (20% Intravascular Perfluorochemical Emulsion) is a registered trademark of The Green Cross Corporation, Osaka, Japan.
Kent K, Cleman M, Cowley M, Forman M, Jaffe C, Kaplan M, King S, Krucoff M, Lassar T, McAuley B, Smith R, Wisdom C, Wohlgelernter D. Reduction of myocardial ischemia during percutaneous transluminal coronary angioplasty with oxygenated Fluosol®11Fluosol® (20% Intravascular Perfluorochemical Emulsion) is a registered trademark of The Green Cross Corporation, Osaka, Japan. The American Journal Of Cardiology 1990, 66: 279-284. PMID: 2195864, DOI: 10.1016/0002-9149(90)90836-p.Peer-Reviewed Original ResearchConceptsOxygen-carrying perfluorochemical emulsionFluosol perfusionAngioplasty patientsMyocardial ischemiaPerfluorochemical emulsionBaseline levelsGlobal left ventricular ejection fractionLeft ventricular ejection fractionPercutaneous transluminal coronary angioplastyRegional wall dysfunctionSevere anginal painTransluminal coronary angioplastyVentricular ejection fractionST-segment changesAnginal painGreen Cross CorporationCoronary angioplastyEjection fractionMulticenter trialRoutine angioplastyVentricular functionBalloon occlusionBalloon deflationPatient populationBalloon inflationMetabolic and functional effects of perfluorocarbon distal perfusion during coronary angioplasty
Young L, Jaffe C, Revkin J, McNulty P, Cleman M. Metabolic and functional effects of perfluorocarbon distal perfusion during coronary angioplasty. The American Journal Of Cardiology 1990, 65: 986-990. PMID: 2327360, DOI: 10.1016/0002-9149(90)91001-m.Peer-Reviewed Original ResearchConceptsGreat cardiac veinDistal perfusionLactate releaseEjection fractionVentricular functionCardiac veinBalloon inflationLeft ventricular ejection fractionDistal coronary perfusionMyocardial lactate metabolismVentricular ejection fractionMyocardial lactate releaseRegional contractile functionNet lactate extractionNet lactate releaseCoronary angioplastyLeft anteriorCoronary perfusionLactate extractionContractile functionPerfusionAngioplastyLactate concentrationLactate metabolismOxygenated perfluorocarbon
1988
Preservation of left ventricular ejection fraction during percutaneous transluminal coronary angioplasty by distal transcatheter coronary perfusion of oxygenated fluosol DA 20%
Jaffe C, Wohlgelernter D, Cabin H, Bowman L, Deckelbaum L, Remetz M, Cleman M. Preservation of left ventricular ejection fraction during percutaneous transluminal coronary angioplasty by distal transcatheter coronary perfusion of oxygenated fluosol DA 20%. American Heart Journal 1988, 115: 1156-1164. PMID: 2967624, DOI: 10.1016/0002-8703(88)90002-6.Peer-Reviewed Original ResearchConceptsVentricular ejection fractionPercutaneous transluminal coronary angioplastyTransluminal coronary angioplastyEjection fractionCoronary perfusionBalloon inflationCoronary angioplastyDistal coronary perfusionLeft ventricular functionDistal coronary arteriesEnd-diastolic volumeEnd-systolic volumeTwo-dimensional echocardiographyFluosol-DA 20Area-length methodOxygenated perfluorocarbon emulsionDynamics of early and late left ventricular filling determined by Doppler two-dimensional echocardiography during percutaneous transluminal coronary angioplasty
Bowman L, Cleman M, Cabin H, Zaret B, Jaffe C. Dynamics of early and late left ventricular filling determined by Doppler two-dimensional echocardiography during percutaneous transluminal coronary angioplasty. The American Journal Of Cardiology 1988, 61: 541-545. PMID: 2964191, DOI: 10.1016/0002-9149(88)90761-8.Peer-Reviewed Original ResearchConceptsPercutaneous transluminal coronary angioplastyEarly peak filling ratePeak filling rateLate filling ratioTransluminal coronary angioplastyAtrial stroke volumeLeft ventricular fillingBalloon inflationVentricular fillingCoronary angioplastyStroke volumeMean pulmonary artery wedge pressureDominant right coronary arteryPulmonary artery wedge pressureLate ventricular fillingRight coronary arteryGlobal systolic functionTwo-dimensional echocardiographyInfluence of ischemiaFilling rateWedge pressureLeft circumflexSystolic functionCoronary occlusionBalloon deflation
1987
Silent ischemia during coronary occlusion produced by balloon inflation: Relation to regional myocardial dysfunction
Wohlgelernter D, Jaffe C, Cabin H, Yeatman L, Cleman M. Silent ischemia during coronary occlusion produced by balloon inflation: Relation to regional myocardial dysfunction. Journal Of The American College Of Cardiology 1987, 10: 491-498. PMID: 2957410, DOI: 10.1016/s0735-1097(87)80189-4.Peer-Reviewed Original ResearchMeSH KeywordsAngina PectorisAngioplasty, BalloonCoronary DiseaseEchocardiographyElectrocardiographyHeartHumansProspective StudiesConceptsBalloon inflationAsymptomatic groupCoronary angioplastyMyocardial ischemiaPercutaneous transluminal coronary angioplastyRegional left ventricular dysfunctionGlobal left ventricular wall motionTwo-dimensional echocardiographic recordingsLeft ventricular dysfunctionStable exertional anginaAbsence of anginaSilent myocardial ischemiaTransluminal coronary angioplastyRegional myocardial dysfunctionLeft ventricular wall motionST-segment changesSignificant differencesVentricular wall motionPain interviewExertional anginaSilent ischemiaVentricular dysfunctionObstructive lesionsEchocardiographic assessmentComorbid conditions
1986
Prevention of ischemia during percutaneous transluminal coronary angioplasty by transcatheter infusion of oxygenated Fluosol DA 20%.
Cleman M, Jaffee C, Wohlgelernter D. Prevention of ischemia during percutaneous transluminal coronary angioplasty by transcatheter infusion of oxygenated Fluosol DA 20%. Circulation 1986, 74: 555-562. PMID: 2943533, DOI: 10.1161/01.cir.74.3.555.Peer-Reviewed Original ResearchConceptsPercutaneous transluminal coronary angioplastyFluosol-DA 20Regional left ventricular dysfunctionLeft ventricular dysfunctionTransluminal coronary angioplastyTranscatheter infusionBalloon inflationVentricular dysfunctionCoronary angioplastyCatheter balloon inflationLeft ventricular reserveSubsequent myocardial ischemiaCoronary blood flowLactate solutionPrevention of ischemiaLonger inflation timesTwo-dimensional echocardiographyRinger's lactate solutionRegional wall motionRegional contractionDilating catheterDistal infusionVentricular reserveIschemic riskIntracoronary infusionRegional myocardial dysfunction during coronary angioplasty: Evaluation by two-dimensional echocardiography and 12 lead electrocardiography
Wohlgelernter D, Cleman M, Highman H, Fetterman R, Duncan J, Zaret B, Jaffe C. Regional myocardial dysfunction during coronary angioplasty: Evaluation by two-dimensional echocardiography and 12 lead electrocardiography. Journal Of The American College Of Cardiology 1986, 7: 1245-1254. PMID: 2940283, DOI: 10.1016/s0735-1097(86)80143-7.Peer-Reviewed Original ResearchConceptsLeft ventricular dysfunctionRegional left ventricular dysfunctionTwo-dimensional echocardiographyCoronary arteryVentricular dysfunctionCoronary angioplastyIschemic effectsBalloon inflationGroup BNormal left ventricular functionPercutaneous transluminal coronary angioplastyLead electrocardiographic recordingsMagnitude of dysfunctionTransient total occlusionEvidence of ischemiaIschemic electrocardiographic changesTransluminal coronary angioplastyLeft ventricular functionLeft ventricular wall motionRegional myocardial dysfunctionWall motion abnormalitiesRecovery of functionRegional left ventricular wall motionOnset of dysfunctionVentricular wall motionOxygenated fluosol DA-20% distal infusion during coronary angioplasty protects myocardial function.
Jaffe C, Wohlgelernter D, Highman H, Cleman M. Oxygenated fluosol DA-20% distal infusion during coronary angioplasty protects myocardial function. Progress In Clinical And Biological Research 1986, 211: 21-7. PMID: 2938192.Peer-Reviewed Original Research