2016
Impact of Glycoprotein IIb/IIIa Inhibitors Use on Outcomes After Lower Extremity Endovascular Interventions From Nationwide Inpatient Sample (2006–2011)
Arora S, Panaich SS, Patel N, Patel NJ, Lahewala S, Thakkar B, Savani C, Jhamnani S, Singh V, Patel N, Patel S, Sonani R, Patel A, Tripathi B, Deshmukh A, Chothani A, Patel J, Bhatt P, Mohamad T, Remetz MS, Curtis JP, Attaran RR, Mena CI, Schreiber T, Grines C, Cleman M, Forrest JK, Badheka AO. Impact of Glycoprotein IIb/IIIa Inhibitors Use on Outcomes After Lower Extremity Endovascular Interventions From Nationwide Inpatient Sample (2006–2011). Catheterization And Cardiovascular Interventions 2016, 88: 605-616. PMID: 26914274, DOI: 10.1002/ccd.26452.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAmputation, SurgicalCross-Sectional StudiesDatabases, FactualDrug CostsEndovascular ProceduresFemaleHospital CostsHospital MortalityHumansLimb SalvageLogistic ModelsLower ExtremityMaleMiddle AgedMultivariate AnalysisOdds RatioPeripheral Arterial DiseasePlatelet Aggregation InhibitorsPlatelet Glycoprotein GPIIb-IIIa ComplexPropensity ScoreRisk FactorsTime FactorsTreatment OutcomeUnited StatesYoung AdultConceptsGlycoprotein IIb/IIIa inhibitorsPeripheral endovascular interventionsHospital mortalityHospitalization costsEndovascular interventionGPI useAmputation rateUtilization Project Nationwide Inpatient Sample databaseTwo-level hierarchical multivariateIIb/IIIa inhibitorsNationwide Inpatient Sample databaseLower amputation ratesPaucity of dataHospital outcomesPostprocedural complicationsSecondary outcomesPropensity matchingStudy cohortHealthcare costsICD-9Multivariate analysisStudy outcomesSample databaseMortalityHierarchical multivariate
2015
Intravascular Ultrasound in Lower Extremity Peripheral Vascular Interventions
Panaich SS, Arora S, Patel N, Patel NJ, Savani C, Patel A, Thakkar B, Singh V, Patel S, Patel N, Agnihotri K, Bhatt P, Deshmukh A, Gupta V, Attaran RR, Mena CI, Grines CL, Cleman M, Forrest JK, Badheka AO. Intravascular Ultrasound in Lower Extremity Peripheral Vascular Interventions. Journal Of Endovascular Therapy 2015, 23: 65-75. PMID: 26637836, DOI: 10.1177/1526602815620780.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAmputation, SurgicalChi-Square DistributionCost-Benefit AnalysisDatabases, FactualEndovascular ProceduresFemaleHospital CostsHospital MortalityHumansLimb SalvageLinear ModelsLower ExtremityMaleMiddle AgedMultivariate AnalysisOdds RatioPeripheral Vascular DiseasesPractice Patterns, Physicians'Risk FactorsTime FactorsTreatment OutcomeUltrasonography, InterventionalUnited StatesYoung AdultConceptsLower limb endovascular interventionsPostprocedural complicationsHospitalization costsEndovascular interventionHospital mortalityAmputation rateOdds ratioNonsignificant increaseUtilization Project Nationwide Inpatient Sample databaseTwo-level hierarchical multivariateICD-9 procedure codesNationwide Inpatient Sample databasePeripheral vascular proceduresCo-primary outcomesLower amputation ratesPeripheral vascular interventionsPeripheral endovascular interventionsConfidence intervalsIVUS useIVUS utilizationSecondary outcomesStudy cohortVascular proceduresVascular interventionsHealthcare costsEffect of Hospital Volume on Outcomes of Transcatheter Mitral Valve Repair: An Early US Experience
Patel NJ, Badheka AO, Jhamnani S, Panaich SS, Singh V, Patel N, Arora S, Grines CL, Cleman M, Forrest JK. Effect of Hospital Volume on Outcomes of Transcatheter Mitral Valve Repair: An Early US Experience. Journal Of Interventional Cardiology 2015, 28: 464-471. PMID: 26489974, DOI: 10.1111/joic.12228.Peer-Reviewed Original ResearchConceptsTranscatheter mitral valve repairMitral valve repairNationwide Inpatient Sample databasePeri-procedural complicationsHospital volumeLength of stayHospital mortalityValve repairHospitalization costsUtilization Project Nationwide Inpatient Sample databaseICD-9-CM procedure codesPercutaneous mitral valve repairEarly US ExperienceHigher hospital volumePost-procedural complicationsCross-sectional studyFirst tertileOverall cohortThird tertilePrimary outcomeSecond tertileTMVR proceduresMitral regurgitationBaseline burdenMean ageMechanical Circulatory Support Devices and Transcatheter Aortic Valve Implantation (from the National Inpatient Sample)
Singh V, Patel SV, Savani C, Patel NJ, Patel N, Arora S, Panaich SS, Deshmukh A, Cleman M, Mangi A, Forrest JK, Badheka AO. Mechanical Circulatory Support Devices and Transcatheter Aortic Valve Implantation (from the National Inpatient Sample). The American Journal Of Cardiology 2015, 116: 1574-1580. PMID: 26434512, DOI: 10.1016/j.amjcard.2015.08.020.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve implantationMechanical circulatory support devicesAortic valve implantationCirculatory support devicesMCS devicesValve implantationHigh-risk surgical patientsPropensity score-matched analysisClinical Modification procedure codesSupport devicesVentricular fibrillation arrestNationwide Inpatient SampleCost of hospitalizationShort-term useSignificant increaseUnacceptably high ratesInhospital mortalityInhospital outcomesCardiogenic shockIndependent predictorsSurgical patientsNinth RevisionTAVI procedureTransapical accessInpatient SampleComparison of Inhospital Outcomes of Surgical Aortic Valve Replacement in Hospitals With and Without Availability of a Transcatheter Aortic Valve Implantation Program (from a Nationally Representative Database)
Singh V, Badheka AO, Patel SV, Patel NJ, Thakkar B, Patel N, Arora S, Patel N, Patel A, Savani C, Ghatak A, Panaich SS, Jhamnani S, Deshmukh A, Chothani A, Sonani R, Patel A, Bhatt P, Dave A, Bhimani R, Mohamad T, Grines C, Cleman M, Forrest JK, Mangi A. Comparison of Inhospital Outcomes of Surgical Aortic Valve Replacement in Hospitals With and Without Availability of a Transcatheter Aortic Valve Implantation Program (from a Nationally Representative Database). The American Journal Of Cardiology 2015, 116: 1229-1236. PMID: 26297512, DOI: 10.1016/j.amjcard.2015.07.039.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAortic ValveBicuspid Aortic Valve DiseaseCardiac Care FacilitiesDatabases, FactualFemaleHeart Defects, CongenitalHeart Valve DiseasesHospital MortalityHospitalizationHumansMaleMiddle AgedPropensity ScoreTranscatheter Aortic Valve ReplacementTreatment OutcomeUnited StatesConceptsSurgical aortic valve replacementTranscatheter aortic valve implantation (TAVI) programCo-morbidity scoreAortic valve replacementTAVI programNationwide Inpatient SampleTAVI groupComplication rateInhospital outcomesValve replacementConventional surgical aortic valve replacementCharlson co-morbidity scoreClinical Modification procedure codesLower inhospital mortalityAortic valve diseaseCost of hospitalizationImplantation programYears of ageInhospital mortalitySAVR proceduresHospital stayValve diseaseNinth RevisionMean agePatient populationMultivessel Percutaneous Coronary Interventions in the United States
Arora S, Panaich SS, Patel NJ, Patel N, Solanki S, Deshmukh A, Singh V, Lahewala S, Savani C, Thakkar B, Dave A, Patel A, Bhatt P, Sonani R, Patel A, Cleman M, Forrest JK, Schreiber T, Badheka AO, Grines C. Multivessel Percutaneous Coronary Interventions in the United States. Angiology 2015, 67: 326-335. PMID: 26145455, DOI: 10.1177/0003319715593853.Peer-Reviewed Original ResearchConceptsMultivessel percutaneous coronary interventionLength of stayNationwide Inpatient SamplePercutaneous coronary interventionInhospital mortalityStent PCICoronary interventionSecondary outcomesHospitalization costsUtilization Project Nationwide Inpatient SampleMultivessel coronary artery diseaseShorter LOSClinical Modification procedure codesHigher inhospital mortalityHigh-volume hospitalsCoronary artery diseaseSignificant mortality riskAcute myocardial infarctionLower hospitalization costsCost of careDifferent International ClassificationInhospital outcomesCause mortalityPeriprocedural complicationsVolume hospitalsImpact of Hospital Volume on Outcomes of Lower Extremity Endovascular Interventions (Insights from the Nationwide Inpatient Sample [2006 to 2011])
Arora S, Panaich SS, Patel N, Patel N, Lahewala S, Solanki S, Patel P, Patel A, Manvar S, Savani C, Tripathi B, Thakkar B, Jhamnani S, Singh V, Patel S, Patel J, Bhimani R, Mohamad T, Remetz MS, Curtis JP, Attaran RR, Grines C, Mena CI, Cleman M, Forrest J, Badheka AO. Impact of Hospital Volume on Outcomes of Lower Extremity Endovascular Interventions (Insights from the Nationwide Inpatient Sample [2006 to 2011]). The American Journal Of Cardiology 2015, 116: 791-800. PMID: 26100585, DOI: 10.1016/j.amjcard.2015.05.050.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overEndovascular ProceduresFemaleFollow-Up StudiesHospital CostsHospital MortalityHospitals, High-VolumeHospitals, Low-VolumeHumansIncidenceInpatientsLower ExtremityMaleMiddle AgedPeripheral Arterial DiseasePostoperative ComplicationsPostoperative PeriodPrognosisRegistriesRetrospective StudiesUnited StatesYoung AdultConceptsPeripheral endovascular interventionsHospitalization costsEndovascular interventionInhospital mortalityAmputation rateHospital volumePrimary outcomeCharlson co-morbidity index scoreUtilization Project Nationwide Inpatient Sample databaseLower Extremity Endovascular InterventionsTwo-level hierarchical multivariateNationwide Inpatient Sample databaseHospital volume quartilesCo-morbidity statusHospital procedural volumeLower amputation ratesAppropriate International ClassificationHigh-volume centersAnnual institutional volumeWeekend admissionSecondary outcomesPostprocedural complicationsStudy cohortNinth RevisionVolume centersComparison of Inhospital Outcomes and Hospitalization Costs of Peripheral Angioplasty and Endovascular Stenting
Panaich SS, Arora S, Patel N, Patel NJ, Lahewala S, Solanki S, Manvar S, Savani C, Jhamnani S, Singh V, Patel SV, Thakkar B, Patel A, Deshmukh A, Chothani A, Bhatt P, Savani GT, Patel J, Mavani K, Bhimani R, Tripathi B, Mohamad T, Remetz MS, Curtis JP, Attaran RR, Grines C, Mena CI, Cleman M, Forrest JK, Badheka AO. Comparison of Inhospital Outcomes and Hospitalization Costs of Peripheral Angioplasty and Endovascular Stenting. The American Journal Of Cardiology 2015, 116: 634-641. PMID: 26096999, DOI: 10.1016/j.amjcard.2015.05.031.Peer-Reviewed Original ResearchConceptsLower amputation ratesInhospital mortalityPostprocedural complicationsHospitalization costsEndovascular stentingAmputation rateUtilization Project Nationwide Inpatient Sample databaseTwo-level hierarchical multivariateNationwide Inpatient Sample databaseComposite end pointPeripheral arterial diseaseHigher hospitalization costsAppropriate International ClassificationPeripheral endovascular interventionsInhospital outcomesSecondary outcomesPeripheral angioplastyPrimary outcomeArterial diseaseClinical outcomesStudy cohortNinth RevisionPatency ratesEndovascular interventionAngioplastyEffect of Hospital Volume on Outcomes of Transcatheter Aortic Valve Implantation
Badheka AO, Patel NJ, Panaich SS, Patel SV, Jhamnani S, Singh V, Pant S, Patel N, Patel N, Arora S, Thakkar B, Manvar S, Dhoble A, Patel A, Savani C, Patel J, Chothani A, Savani GT, Deshmukh A, Grines CL, Curtis J, Mangi AA, Cleman M, Forrest JK. Effect of Hospital Volume on Outcomes of Transcatheter Aortic Valve Implantation. The American Journal Of Cardiology 2015, 116: 587-594. PMID: 26092276, DOI: 10.1016/j.amjcard.2015.05.019.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve implantationLength of stayShorter LOSNationwide Inpatient Sample databaseInhospital mortality rateAortic valve implantationLower hospitalization costsHospital volumeInhospital mortalityComplication rateValve implantationHospitalization costsMortality rateUtilization Project Nationwide Inpatient Sample databaseHigher annual hospital volumeOverall inhospital mortality rateMedian LOSClinical Modification procedure codesMultivariate logistic regression modelAnnual hospital volumeLowest volume quartileLow-volume hospitalsPostprocedural complication rateCost of hospitalizationCross-sectional studyTrends of Hospitalizations in the United States from 2000 to 2012 of Patients >60 Years With Aortic Valve Disease
Badheka AO, Singh V, Patel NJ, Arora S, Patel N, Thakkar B, Jhamnani S, Pant S, Chothani A, Macon C, Panaich SS, Patel J, Manvar S, Savani C, Bhatt P, Panchal V, Patel N, Patel A, Patel D, Lahewala S, Deshmukh A, Mohamad T, Mangi AA, Cleman M, Forrest JK. Trends of Hospitalizations in the United States from 2000 to 2012 of Patients >60 Years With Aortic Valve Disease. The American Journal Of Cardiology 2015, 116: 132-141. PMID: 25983278, DOI: 10.1016/j.amjcard.2015.03.053.Peer-Reviewed Original ResearchConceptsAortic valve diseaseCost of hospitalizationInhospital mortalityHeart failureValve diseaseHigh burdenEconomic burdenFrequent coexisting conditionsOverall inhospital mortalitySubgroup of patientsValvular heart diseaseInnovative therapeutic optionsNationwide Inpatient SamplePrincipal discharge diagnosisNumber of hospitalizationsTrend of hospitalizationsPublic health systemRenal failureAortic stenosisDischarge diagnosisNinth RevisionTherapeutic optionsPatient populationInpatient SampleCoexisting conditionsComparison of Inhospital Mortality, Length of Hospitalization, Costs, and Vascular Complications of Percutaneous Coronary Interventions Guided by Ultrasound Versus Angiography
Singh V, Badheka AO, Arora S, Panaich SS, Patel NJ, Patel N, Pant S, Thakkar B, Chothani A, Deshmukh A, Manvar S, Lahewala S, Patel J, Patel S, Jhamnani S, Bhinder J, Patel P, Savani GT, Patel A, Mohamad T, Gidwani UK, Brown M, Forrest JK, Cleman M, Schreiber T, Grines C. Comparison of Inhospital Mortality, Length of Hospitalization, Costs, and Vascular Complications of Percutaneous Coronary Interventions Guided by Ultrasound Versus Angiography. The American Journal Of Cardiology 2015, 115: 1357-1366. PMID: 25824542, DOI: 10.1016/j.amjcard.2015.02.037.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overCoronary AngiographyCoronary Artery DiseaseCoronary VesselsCosts and Cost AnalysisFemaleFollow-Up StudiesHealth Care CostsHospital MortalityHumansLength of StayMaleMiddle AgedPercutaneous Coronary InterventionPostoperative ComplicationsRetrospective StudiesSurgery, Computer-AssistedUltrasonography, InterventionalUnited StatesYoung AdultConceptsPercutaneous coronary interventionCo-morbidity burdenInhospital mortalityAcute myocardial infarctionHospital stayCoronary interventionVascular complicationsMyocardial infarctionConventional angiography-guided PCIOutcomes of PCIAngiography-guided percutaneous coronary interventionDrug-eluting stent eraHierarchical mixed-effects logistic regression modelsHigher co-morbidity burdenUse of IVUSHigher hospital volumeLength of hospitalizationIntravascular ultrasound guidanceSubgroup of patientsNationwide Inpatient SampleCost of hospitalizationSignificant predictorsMixed effects logistic regression modelsMixed-effects linear regression modelsCost of care
2014
Comparison of Outcomes of Balloon Aortic Valvuloplasty Plus Percutaneous Coronary Intervention Versus Percutaneous Aortic Balloon Valvuloplasty Alone During the Same Hospitalization in the United States
Singh V, Patel NJ, Badheka AO, Arora S, Patel N, Macon C, Savani GT, Manvar S, Patel J, Thakkar B, Panchal V, Solanki S, Patel N, Chothani A, Panaich SS, Ram V, Kliger CA, Schreiber T, Neill W, Cohen MG, Alfonso CE, Grines CL, Mangi A, Pfau S, Forrest JK, Cleman M, Makkar R. Comparison of Outcomes of Balloon Aortic Valvuloplasty Plus Percutaneous Coronary Intervention Versus Percutaneous Aortic Balloon Valvuloplasty Alone During the Same Hospitalization in the United States. The American Journal Of Cardiology 2014, 115: 480-486. PMID: 25543235, DOI: 10.1016/j.amjcard.2014.11.032.Peer-Reviewed Original ResearchConceptsPercutaneous coronary interventionLength of stayCost of hospitalizationSame hospitalizationPCI groupHospital mortalityComplication rateConcomitant percutaneous coronary interventionHigh surgical risk patientsPercutaneous aortic balloon valvuloplastySimilar LOSAortic balloon valvuloplastySurgical risk patientsBalloon aortic valvuloplastyHospital mortality rateHigher hospitalization costsInvasive endovascular therapiesComparison of outcomesAortic valvuloplastyBalloon valvuloplastyWeekend admissionCoronary interventionOnly patientsRisk patientsSecondary outcomes