2025
5-Year Outcomes After Transcatheter or Surgical Aortic Valve Replacement in Low-Risk Patients With Aortic Stenosis
Forrest J, Yakubov S, Deeb G, Gada H, Mumtaz M, Ramlawi B, Bajwa T, Crouch J, Merhi W, Sang S, Kleiman N, Petrossian G, Robinson N, Sorajja P, Iskander A, Berthoumieu P, Tchétché D, Feindel C, Horlick E, Saito S, Oh J, Jung Y, Reardon M, Investigators L. 5-Year Outcomes After Transcatheter or Surgical Aortic Valve Replacement in Low-Risk Patients With Aortic Stenosis. Journal Of The American College Of Cardiology 2025, 85: 1523-1532. PMID: 40158212, DOI: 10.1016/j.jacc.2025.03.004.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve replacementTranscatheter aortic valve replacement groupEvolut Low Risk TrialEndpoint of all-cause mortalityAll-cause mortalityNoninferior to surgeryLow-risk patientsAortic valve replacementSevere aortic stenosisSurgery groupKaplan-Meier estimatesLow-risk trialsAortic stenosisDisabling strokeValve replacementRisk trialsSurgical aortic valve replacementLost to follow-upRates of all-cause mortalityKansas City Cardiomyopathy Questionnaire summary scoreLow surgical riskQuestionnaire summary scoreQuality-of-life outcomesAttempted implantReintervention rateTranscatheter vs Surgical Aortic Valve Replacement in Lower-Risk Patients An Updated Meta-Analysis of Randomized Controlled Trials
Reddy R, Howard J, Mack M, Reardon M, Jørgensen T, Hørsted Thyregod H, Toff W, Van Mieghem N, Vora A, Makkar R, Kapadia S, Forrest J, Leon M, Ahmad Y. Transcatheter vs Surgical Aortic Valve Replacement in Lower-Risk Patients An Updated Meta-Analysis of Randomized Controlled Trials. Journal Of The American College Of Cardiology 2025, 85: 926-940. PMID: 40044297, DOI: 10.1016/j.jacc.2024.12.031.Peer-Reviewed Original ResearchConceptsSurgical aortic valve replacementTranscatheter aortic valve replacementLower-risk patientsAortic valve replacementPooled survival analysisValve replacementIndividual participant dataPairwise meta-analysesFollow-upMeta-analysis of randomized controlled trialsLonger-term clinical outcomesReduced hazard of deathSevere aortic stenosisFixed effect assumptionsComposite of deathLonger-term follow-upAll-cause deathMean survival time modelsMeta-analysesHazard of deathRate of strokeRandomized controlled trialsSurvival time modelFrailty termProportional odds model
2024
Inflow-to-Outflow Stent Frame Expansion, Ellipticity, and Decoupling in Evolut TAVR: Implications for Mid-term Hemodynamic Performance
Puri R, Spencer J, Tchétché D, Van Mieghem N, Forrest J, Reardon M, Sanchez J, Caballero A, Blanke P, Leipsic J, Sorajja P, Deeb G, Fukuhara S, Lucas L, Oyekunle T, Tang G. Inflow-to-Outflow Stent Frame Expansion, Ellipticity, and Decoupling in Evolut TAVR: Implications for Mid-term Hemodynamic Performance. Journal Of The Society For Cardiovascular Angiography & Interventions 2024, 4: 102448. PMID: 40061419, PMCID: PMC11887556, DOI: 10.1016/j.jscai.2024.102448.Peer-Reviewed Original ResearchTranscatheter aortic valve replacementTranscatheter aortic valveFrame deformationHypoattenuated leaflet thickeningEffective orifice areaFrame expansionHemodynamic performanceLeaflet thickeningSelf-expanding transcatheter aortic valve replacementLeaflet regionsOrifice areaDays post-TAVRAortic valve replacementNative aortic annulusInflow geometriesEllipticity ratioVariable ellipticityComputed tomography imagesAortic annulusValve replacementParavalvular regurgitationAnnular levelPost-TAVRAortic valveFour-year outcomes after transcatheter or contemporary surgical aortic valve replacement from the Evolut Low Risk trial
Ramlawi B, Deeb G, Mumtaz M, Bajwa T, Rovin J, Yakubov S, Jung Y, Reardon M, Forrest J. Four-year outcomes after transcatheter or contemporary surgical aortic valve replacement from the Evolut Low Risk trial. Journal Of Thoracic And Cardiovascular Surgery 2024, 170: e16-e26. PMID: 39181441, DOI: 10.1016/j.jtcvs.2024.08.023.Peer-Reviewed Original ResearchIn-Hospital Outcomes and 30-Day Readmission Rate After Transcatheter and Surgical Aortic Valve Replacement in Liver Cirrhosis: A Contemporary Propensity-Matched Analysis
Aggarwal A, Jang S, Vardhan S, Webber F, Alam M, Vardhan M, Lancaster G, Ahmad Y, Vora A, Zarich S, Inglessis-Azuaje I, Elmariah S, Forrest J, Davila C. In-Hospital Outcomes and 30-Day Readmission Rate After Transcatheter and Surgical Aortic Valve Replacement in Liver Cirrhosis: A Contemporary Propensity-Matched Analysis. Structural Heart 2024, 8: 100327. PMID: 39670045, PMCID: PMC11632700, DOI: 10.1016/j.shj.2024.100327.Peer-Reviewed Original ResearchSurgical aortic valve replacementTranscatheter aortic valve replacementAortic valve replacementTranscatheter aortic valve replacement groupValve replacementIn-hospital mortalityHepatorenal syndromeReadmission ratesCardiogenic shockLiver cirrhosisVascular complicationsIn-hospitalOutcomes of transcatheter aortic valve replacementSurgical risk prediction modelsSurgical aortic valve replacement groupAssociated with significantly lower ratesRates of in-hospital mortalityLimited contemporary dataIn-hospital outcomesSignificantly lower ratesNationwide Readmissions DatabaseCardiac surgeryPeriprocedural morbidityTherapeutic optionsClinical characteristicsTranscatheter or Surgical Aortic Valve Replacement in Women With Small Annuli at Low or Intermediate Surgical Risk
Modine T, Forrest J, Van Mieghem N, Deeb G, Yakubov S, Ali W, Tchétché D, Lam K, Oh J, Huang J, Mehran R, Reardon M. Transcatheter or Surgical Aortic Valve Replacement in Women With Small Annuli at Low or Intermediate Surgical Risk. The American Journal Of Cardiology 2024, 223: 147-155. PMID: 38641189, DOI: 10.1016/j.amjcard.2024.04.013.Peer-Reviewed Original ResearchTranscatheter aortic valve replacementAortic valve replacementIntermediate surgical riskValve replacementSurgical riskAortic stenosisTranscatheter aortic valve replacement groupImpact of transcatheter aortic valve replacementSurgical aortic valve replacementMid-term clinical outcomesPatient-prothesis mismatchSmall aortic annulusMidterm clinical outcomesSevere aortic stenosisSelf-expandingEffective orifice areaAll-cause mortalityEvaluated 2 yearsPost hoc analysisRandomized controlled trialsAortic annulusSurgical groupPrimary endpointHemodynamic outcomesClinical outcomesReinterventions After CoreValve/Evolut Transcatheter or Surgical Aortic Valve Replacement for Treatment of Severe Aortic Stenosis
Grubb K, Lisko J, O'Hair D, Merhi W, Forrest J, Mahoney P, Van Mieghem N, Windecker S, Yakubov S, Williams M, Chetcuti S, Deeb G, Kleiman N, Althouse A, Reardon M. Reinterventions After CoreValve/Evolut Transcatheter or Surgical Aortic Valve Replacement for Treatment of Severe Aortic Stenosis. JACC Cardiovascular Interventions 2024, 17: 1007-1016. PMID: 38573257, DOI: 10.1016/j.jcin.2024.01.292.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAortic ValveAortic Valve StenosisFemaleHeart Valve ProsthesisHeart Valve Prosthesis ImplantationHumansIncidenceMalePostoperative ComplicationsProsthesis DesignRandomized Controlled Trials as TopicRetreatmentRisk AssessmentRisk FactorsSeverity of Illness IndexTime FactorsTranscatheter Aortic Valve ReplacementTreatment OutcomeConceptsSurgical aortic valve replacementTranscatheter aortic valve replacementIncidence of reinterventionAortic valve replacementCumulative incidence of reinterventionValve replacementValve reinterventionCumulative incidenceCoreValve transcatheter aortic valve replacementLow incidence of reinterventionSurgical aortic valve replacement patientsSingle-arm studyFirst-generation CoreValveEvolut R/ProParavalvular regurgitationReinterventionRandomized trialsLow incidenceCoreValvePooled dataTranscatheterIncidenceTreatmentYearsEndocarditisRacial/Ethnic Disparities in Aortic Valve Replacement Among Medicare Beneficiaries in the United States, 2012-2019
Gupta A, Mori M, Wang Y, Pawar S, Vahl T, Nazif T, Onuma O, Yong C, Sharma R, Kirtane A, Forrest J, George I, Kodali S, Chikwe J, Geirsson A, Makkar R, Leon M, Krumholz H. Racial/Ethnic Disparities in Aortic Valve Replacement Among Medicare Beneficiaries in the United States, 2012-2019. The American Journal Of Medicine 2024, 137: 321-330.e7. PMID: 38190959, PMCID: PMC11019903, DOI: 10.1016/j.amjmed.2023.12.026.Peer-Reviewed Original ResearchAortic valve replacementRace/ethnicityValve replacementAortic stenosisWhite patientsMedicare beneficiariesSurgical aortic valve replacement (SAVR) proceduresCross-sectional cohort studyAortic valve replacement proceduresAortic stenosis treatmentRacial/Ethnic DisparitiesValve replacement proceduresSelf-reported race/ethnicityRace-related differencesIndex admissionIndex hospitalizationCohort studyAsian patientsPrincipal diagnosisProcedural outcomesStenosis treatmentCare spectrumPatientsEthnic disparitiesStenosis
2023
Feasibility of Coronary Access Following Redo-TAVR for Evolut Failure: A Computed Tomography Simulation Study
Tang G, Spencer J, Rogers T, Grubb K, Gleason P, Gada H, Mahoney P, Dauerman H, Forrest J, Reardon M, Blanke P, Leipsic J, Abdel-Wahab M, Attizzani G, Puri R, Caskey M, Chung C, Chen Y, Dudek D, Allen K, Chhatriwalla A, Htun W, Blackman D, Tarantini G, Sanchez J, Schwartz G, Popma J, Sathananthan J. Feasibility of Coronary Access Following Redo-TAVR for Evolut Failure: A Computed Tomography Simulation Study. Circulation Cardiovascular Interventions 2023, 16: e013238. PMID: 37988439, PMCID: PMC10653288, DOI: 10.1161/circinterventions.123.013238.Peer-Reviewed Original ResearchConceptsRedo-TAVRSAPIEN 3Coronary accessRedo transcatheter aortic valve replacementYounger low-risk patientsFuture coronary accessSAPIEN 3 valveAortic valve replacementLow-risk patientsSelf-expanding valvesPre-TAVR CTValve replacementValve implantationCT planningEvolutImplant positionTomography imagingPatientsCTNodes 4Implant depthTAVRSubstudyNodes 5ValveTCT-133 Reinterventions After CoreValve/Evolut Transcatheter or Surgical Aortic Valve Replacement for Treatment of Severe Aortic Stenosis
Grubb K, Lisko J, O’Hair D, Merhi W, Forrest J, Mahoney P, van Mieghem N, Windecker S, Yakubov S, Chetcuti S, Deeb G, Kleiman N, Althouse A, Reardon M. TCT-133 Reinterventions After CoreValve/Evolut Transcatheter or Surgical Aortic Valve Replacement for Treatment of Severe Aortic Stenosis. Journal Of The American College Of Cardiology 2023, 82: b52. DOI: 10.1016/j.jacc.2023.09.139.Peer-Reviewed Original ResearchEffect of antecedent statin usage on conduction disturbances and arrhythmias after transcatheter aortic valve replacement
Shah T, Maarek R, See C, Huang H, Wang Y, Parise H, Forrest J, Lansky A. Effect of antecedent statin usage on conduction disturbances and arrhythmias after transcatheter aortic valve replacement. Cardiovascular Revascularization Medicine 2023, 59: 3-8. PMID: 37573173, DOI: 10.1016/j.carrev.2023.07.022.Peer-Reviewed Original ResearchConceptsAtrial fibrillationConduction disturbancesPrimary endpointStatin usersPacemaker placementRate of AFTranscatheter aortic valve replacementNew atrial fibrillationNew conduction disturbancesPersistent conduction disturbancesAortic valve replacementLong-term prognosisSmall retrospective studiesSignificant differencesPrior pacemakerIndex hospitalizationIntensity statinsValve replacementConsecutive patientsPropensity matchingProcedural complicationsStatin regimenRetrospective studyStatin usageCardiac proceduresImpact of New‐Onset Conduction Disturbances following Transcatheter Aortic Valve Replacement on Outcomes: A Single‐Center Study
See C, Wang Y, Huang H, Parise H, Yang Y, Tirziu D, Francese D, Papoutsidakis N, Bader E, Kaple R, Cleman M, Lansky A, Forrest J. Impact of New‐Onset Conduction Disturbances following Transcatheter Aortic Valve Replacement on Outcomes: A Single‐Center Study. Journal Of Interventional Cardiology 2023, 2023: 5390338. PMID: 37292113, PMCID: PMC10247319, DOI: 10.1155/2023/5390338.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve replacementNew-onset conduction disturbancesAortic valve replacementPersistent conduction disturbancesConduction disturbancesValve replacementSurgical aortic valve replacementSingle-center retrospective analysisYale-New Haven HospitalSingle-center studyCause mortality ratesCause mortality riskLong-term outcomesNew Haven HospitalPeriprocedural factorsAortic stenosisConsecutive patientsTAVR proceduresTerm outcomesRetrospective analysisMortality riskMortality ratePatientsOutcomesPatient's ECGImpact of aortic valve replacement in symptomatic low-risk patients with less than severe aortic stenosis
Ito S, Laham R, Nkomo V, Forrest J, Reardon M, Little S, Mumtaz M, Gada H, Bajwa T, Langholz D, Heiser J, Chawla A, Jenson B, Attizanni G, Markowitz A, Huang J, Oh J. Impact of aortic valve replacement in symptomatic low-risk patients with less than severe aortic stenosis. Open Heart 2023, 10: e002297. PMID: 37173100, PMCID: PMC10186477, DOI: 10.1136/openhrt-2023-002297.Peer-Reviewed Original ResearchConceptsSevere aortic stenosisAortic valve replacementAortic stenosisSymptomatic patientsValve replacementKansas City Cardiomyopathy Questionnaire overall summary scoreEvolut Low Risk trialSurgical aortic valve replacementLow-risk trialsLow-risk patientsOverall summary scoreRate of deathQuality of lifeDisabling strokeEchocardiographic evidenceIsolated AVRHaemodynamic profileClinical outcomesHaemodynamic outcomesRisk trialsClinical trialsCalcium volumeSummary scoresPatientsCore laboratory measurementsCerebral Embolic Protection in Transcatheter Aortic Valve Replacement
Iskander M, Jamil Y, Forrest J, Madhavan M, Makkar R, Leon M, Lansky A, Ahmad Y. Cerebral Embolic Protection in Transcatheter Aortic Valve Replacement. Structural Heart 2023, 7: 100169. PMID: 37520138, PMCID: PMC10382985, DOI: 10.1016/j.shj.2023.100169.Peer-Reviewed Original ResearchTranscatheter aortic valve replacementCerebral embolic protection devicesCerebral embolic protectionAortic valve replacementEmbolic protection devicesValve replacementEmbolic protectionSymptomatic severe aortic stenosisSevere aortic stenosisLow-risk patientsPredictors of strokeOccurrence of complicationsRisk of strokeRecent trial dataRelevant clinical studiesOverall evidence baseExpansion of TAVRFeared complicationAortic stenosisSurgical riskTreatment optionsWorse outcomesClinical studiesPatientsTrial dataTranscatheter Aortic Valve Replacement in Large Annuli Valves With the Supra-Annular, Self-Expandable Evolut Platform in a Real-World Registry
Dallan L, Tang G, Forrest J, Reardon M, Szeto W, Kodali S, Baeza C, Eisenberg R, Attizzani G. Transcatheter Aortic Valve Replacement in Large Annuli Valves With the Supra-Annular, Self-Expandable Evolut Platform in a Real-World Registry. Circulation Cardiovascular Interventions 2023, 16: e012623. PMID: 36943929, PMCID: PMC10022658, DOI: 10.1161/circinterventions.122.012623.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve replacementAortic valve replacementCardiology Transcatheter Valve Therapy RegistryThoracic Surgeons/American CollegeTranscatheter Valve Therapy RegistryValve replacementAortic stenosisAmerican CollegeMultivariable Cox proportional hazards regression modelsAnnulus sizeCox proportional hazards regression modelProportional hazards regression modelsAortic valve reinterventionTricuspid aortic stenosisReal-world registrySevere aortic stenosisBetter clinical outcomesTreatment of patientsHazards regression modelsComputed tomography angiographyLarge annulusValve reinterventionCause mortalityReadmission ratesValve procedures3-Year Outcomes After Transcatheter or Surgical Aortic Valve Replacement in Low-Risk Patients With Aortic Stenosis
Forrest J, Deeb G, Yakubov S, Gada H, Mumtaz M, Ramlawi B, Bajwa T, Teirstein P, DeFrain M, Muppala M, Rutkin B, Chawla A, Jenson B, Chetcuti S, Stoler R, Poulin M, Khabbaz K, Levack M, Goel K, Tchétché D, Lam K, Tonino P, Ito S, Oh J, Huang J, Popma J, Kleiman N, Reardon M, Investigators L, Sorajja P, Byrne T, Kirshner M, Bajwa T, Crouch J, Coselli J, Silva G, Hebeler R, Stoler R, Islam A, Rousou A, Poulin M, Khabbaz K, Bladergroen M, Fail P, Netherland D, Lam K, Tonino W, Sudre A, Berthoumieu P, Tchétché D, Khalili H, Hughes G, Harrison J, De A, Tsau P, van Mieghem N, Larbalestier R, Yong G, Agarwal S, Martin W, Park S, Kleiman N, Reardon M, Mohammadi S, Rodes-Cabau J, Sparling J, Elkins C, Ganzel B, Matthews R, Starnes V, Ando K, Chevalier B, Farge A, DeFrain M, Muppala M, Combs W, Bagur R, Chu M, Fontana G, Dev V, Leya F, Tuchek J, Inglessis I, Jassar A, Piazza N, Lacappelle K, Steinberg D, Katz M, Wang J, Kozina J, Slachman F, Merritt R, Chawla A, Jensen B, Alvarez J, Gooley R, Smith J, Ibrahim R, Cartier R, Rovin J, Fujita T, Rutkin B, Yakubov S, Song H, Zahr F, Miyagawa S, Rajagopal V, Kauten J, Gada H, Mumtaz M, Bhindi R, Brady P, Batra S, Davis T, Iskander A, Heimansohn D, Hermiller J, Takamisawa I, Haldis T, Yamazaki S, Teirstein P, Tada N, Saito S, Merhi W, Leung S, Muller D, Heijmen R, Petrossian G, Robinson N, Knight P, Ling F, Radhakrishnan S, Fremes S, Lehr E, Gafoor S, Noel T, Walton A, Resar J, Adams D, Sharma S, Lilly S, Tadros P, Zorn G, Dauerman H, Ittleman F, Horlick E, Feindel C, Welt F, Sharma V, Markowitz A, Carroll J, Fullerton D, Griffith B, Gupta A, de Marchena E, Salerno T, Chetcuti S, Deeb G, Sultan I, Goel K, Pasupati S, Kon N, Zhao D, Ramlawi B, Forrest J. 3-Year Outcomes After Transcatheter or Surgical Aortic Valve Replacement in Low-Risk Patients With Aortic Stenosis. Journal Of The American College Of Cardiology 2023, 81: 1663-1674. PMID: 36882136, DOI: 10.1016/j.jacc.2023.02.017.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve replacementAortic valve replacementLow-risk patientsCause mortalityPrimary endpointParavalvular regurgitationValve replacementEvolut Low Risk trialLow surgical risk patientsSurgical aortic valve replacementGreater paravalvular regurgitationLow-risk trialsData comparing outcomesLow-risk studiesSupra-annular valveEchocardiographic outcomesSecondary endpointsSurgery groupTAVR patientsRisk patientsSurgery patientsAortic stenosisPacemaker placementTreatment armsMean ageTranscatheter versus surgical aortic valve replacement in lower-risk and higher-risk patients: a meta-analysis of randomized trials
Ahmad Y, Howard J, Arnold A, Madhavan M, Cook C, Alu M, Mack M, Reardon M, Thourani V, Kapadia S, Thyregod H, Sondergaard L, Jørgensen T, Toff W, Van Mieghem N, Makkar R, Forrest J, Leon M. Transcatheter versus surgical aortic valve replacement in lower-risk and higher-risk patients: a meta-analysis of randomized trials. European Heart Journal 2023, 44: 836-852. PMID: 36660821, DOI: 10.1093/eurheartj/ehac642.Peer-Reviewed Original ResearchConceptsSurgical aortic valve replacementTranscatheter aortic valve implantationHigh-risk patientsLow-risk patientsComposite of deathAortic valve replacementValve replacementMAIN OUTCOMENew-onset atrial fibrillationSignificant differencesRandomized clinical trial dataAcute kidney injuryAortic valve implantationMain clinical outcomesRisk of deathClinical trial dataMajor bleedingKidney injurySecondary endpointsVascular complicationsValve implantationClinical outcomesParavalvular leakRandomized trialsAtrial fibrillation
2022
Propensity-Matched Outcomes Comparing TAVR in Bicuspid vs Surgery in Tricuspid Aortic Valve Stenosis
Deeb G, Yakubov S, Reardon M, Ramlawi B, Chetcuti S, Kleiman N, Zahr F, Song H, Gada H, Mumtaz M, Ito S, Huang J, Forrest J. Propensity-Matched Outcomes Comparing TAVR in Bicuspid vs Surgery in Tricuspid Aortic Valve Stenosis. Journal Of The Society For Cardiovascular Angiography & Interventions 2022, 2: 100525. PMID: 39132531, PMCID: PMC11307701, DOI: 10.1016/j.jscai.2022.100525.Peer-Reviewed Original ResearchTranscatheter aortic valve replacementSurgical aortic valve replacementAortic valve stenosisTricuspid aortic valve stenosisBicuspid aortic valve stenosisAortic valve replacementSAVR patientsValve replacementValve stenosisEvolut Low Risk trialIndependent clinical events committeeLow-risk trialsSerious adverse eventsSevere aortic regurgitationClinical events committeeLow surgical riskLow-risk patientsIndependent core laboratoryEffective orifice areaTAVR groupValve gradientAdverse eventsAortic regurgitationSurgical riskEvents committeeClinical Research on Transcatheter Aortic Valve Replacement for Bicuspid Aortic Valve Disease: Principles, Challenges, and an Agenda for the Future
Ahmad Y, Madhavan M, Baron S, Forrest J, Borger M, Leipsic J, Cavalcante J, Wang D, McCarthy P, Szerlip M, Kapadia S, Makkar R, Mack M, Leon M, Cohen D. Clinical Research on Transcatheter Aortic Valve Replacement for Bicuspid Aortic Valve Disease: Principles, Challenges, and an Agenda for the Future. Structural Heart 2022, 7: 100102. PMID: 37275317, PMCID: PMC10236801, DOI: 10.1016/j.shj.2022.100102.Peer-Reviewed Original ResearchTranscatheter aortic valve replacementBicuspid aortic valve diseaseSurgical aortic valve replacementAortic valve replacementAortic valve diseaseValve replacementClinical researchValve diseaseValvular heart diseaseDesign of RCTsProcedural therapiesProspective registryHeart diseaseExclusion criteriaRisk scorePatientsRCTsDiseaseCardiovascular communityMultidisciplinary workshopSelection biasTrialsInternational expertsPotential studiesRegistryReadmission rates and risk factors for readmission after transcatheter aortic valve replacement in patients with end-stage renal disease
Park DY, An S, Hanna JM, Wang SY, Cruz-Solbes AS, Kochar A, Lowenstern AM, Forrest JK, Ahmad Y, Cleman M, Al Damluji A, Nanna MG. Readmission rates and risk factors for readmission after transcatheter aortic valve replacement in patients with end-stage renal disease. PLOS ONE 2022, 17: e0276394. PMID: 36264931, PMCID: PMC9584363, DOI: 10.1371/journal.pone.0276394.Peer-Reviewed Original ResearchConceptsEnd-stage renal diseaseTranscatheter aortic valve replacementLength of stayAortic valve replacementIndex hospitalizationHospital mortalityReadmission ratesValve replacementRenal diseaseLonger LOSNational Readmission DatabaseRisk of readmissionChronic pulmonary diseaseMultivariable logistic regressionCardiovascular causesCardiovascular readmissionCause readmissionHospital readmissionPulmonary diseaseHospital chargesPoor outcomeRisk factorsHospital costsReadmissionHigher odds
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