2024
Reproducibility of Semi-automated Quantitative Analyses of Tc-99m Pyrophosphate Uptake from Myocardial Perfusion Planar and SPECT Images
Goyal D, Sandoval V, Weyman C, Miller E, Liu Y. Reproducibility of Semi-automated Quantitative Analyses of Tc-99m Pyrophosphate Uptake from Myocardial Perfusion Planar and SPECT Images. Journal Of Medical And Biological Engineering 2024, 45: 84-91. DOI: 10.1007/s40846-024-00924-1.Peer-Reviewed Original ResearchStandardized uptake valueTc-99SPECT imagesStandard uptake value quantificationTransthyretin cardiac amyloidosisH/CL ratioTc-99m PYP uptakeMethodsOur study cohortInter-observer reproducibilityPlanar imagingTechnetium-99mCardiac amyloidosisClinical suspicionSPECT/CT imagingTc-99m PYP imagingTc-99m PYPConsecutive subjectsUptake valueObserver reproducibilityStudy cohortInter-observerPurposeThe aimResultsIntra-observerMyocardial uptakeSPECTReproducibility for quantification of myocardial Tc-99m PYP amyloid uptake in grade 1 patients
Sandoval V, Goyal D, Miller E, Liu Y. Reproducibility for quantification of myocardial Tc-99m PYP amyloid uptake in grade 1 patients. European Heart Journal - Cardiovascular Imaging 2024, 25: jeae142.047. DOI: 10.1093/ehjci/jeae142.047.Peer-Reviewed Original ResearchStandardized uptake valueTc-99m PYP uptakeTc-99Cardiac amyloidosisHeart failureStandard uptake value quantificationStandardized uptake value calculationSPECT imagesIntractable heart failureSystolic heart failureIntroduction of therapyPlanar imagingTc-99m pyrophosphateAmyloid patientsSPECT/CT imagingInter-reproducibilityUptake valueContralateral ratioCoefficient of variationDisease progressionH/M ratioGrade 1Blood poolPatientsH/CL ratio
2018
Quantitative interpretation of FDG PET for cardiac sarcoidosis reclassifies visually interpreted exams and potentially impacts downstream interventions
Varghese M, Smiley D, Bellumkonda L, Rosenfeld LE, Zaret B, Miller EJ. Quantitative interpretation of FDG PET for cardiac sarcoidosis reclassifies visually interpreted exams and potentially impacts downstream interventions. Sarcoidosis, Vasculitis, And Diffuse Lung Diseases 2018, 35: 342-353. PMID: 32476922, PMCID: PMC7170132, DOI: 10.36141/svdld.v35i4.7342.Peer-Reviewed Original Research
2014
Quantitative interpretation of FDG PET/CT with myocardial perfusion imaging increases diagnostic information in the evaluation of cardiac sarcoidosis
Ahmadian A, Brogan A, Berman J, Sverdlov AL, Mercier G, Mazzini M, Govender P, Ruberg FL, Miller EJ. Quantitative interpretation of FDG PET/CT with myocardial perfusion imaging increases diagnostic information in the evaluation of cardiac sarcoidosis. Journal Of Nuclear Cardiology 2014, 21: 925-939. PMID: 24879453, DOI: 10.1007/s12350-014-9901-9.Peer-Reviewed Original ResearchMeSH KeywordsFemaleFluorodeoxyglucose F18Heart DiseasesHumansImage EnhancementImage Interpretation, Computer-AssistedMaleMiddle AgedMultimodal ImagingMyocardial Perfusion ImagingPositron-Emission TomographyRadiopharmaceuticalsReproducibility of ResultsRetrospective StudiesSarcoidosisSensitivity and SpecificityTomography, X-Ray ComputedConceptsFDG PET/CTPET/CTCardiac sarcoidosisStandardized uptake valueMyocardial perfusion imagingClinical eventsPerfusion imagingCardiac FDG PET/CTAdverse clinical eventsOnly independent predictorNegative control studyCS correlatesImmunosuppressive treatmentPrednisone treatmentImmunosuppression treatmentIndependent predictorsFDG uptakeOncologic indicationsPerfusion defectsNegative studiesRepeat examinationLow EFUptake valueControl studyMultivariate analysis
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