Integration of coronary artery calcium scoring from CT attenuation scans by machine learning improves prediction of adverse cardiovascular events in patients undergoing SPECT/CT myocardial perfusion imaging
Feher A, Pieszko K, Miller R, Lemley M, Shanbhag A, Huang C, Miras L, Liu YH, Sinusas AJ, Miller EJ, Slomka PJ. Integration of coronary artery calcium scoring from CT attenuation scans by machine learning improves prediction of adverse cardiovascular events in patients undergoing SPECT/CT myocardial perfusion imaging. Journal Of Nuclear Cardiology 2022, 30: 590-603. PMID: 36195826, DOI: 10.1007/s12350-022-03099-x.Peer-Reviewed Original ResearchConceptsMajor adverse cardiovascular eventsMyocardial perfusion imagingAdverse cardiovascular eventsSPECT myocardial perfusion imagingCAC scoringCardiovascular eventsPrediction of MACECoronary artery calcification (CAC) scoringMACE-free survivalClinical risk factorsCoronary artery calciumCT myocardial perfusion imagingReceiver operator characteristic curveSPECT/CT myocardial perfusion imagingSPECT/CTOperator characteristic curveCT myocardial perfusionArtery calciumCAC scoreAnalysis patientsMACE predictionSingle centerHigher event ratesRisk factorsRisk scoreThe Prognostic Value of CAC Zero Among Individuals Presenting With Chest Pain A Meta-Analysis
Agha AM, Pacor J, Grandhi GR, Mszar R, Khan SU, Parikh R, Agrawal T, Burt J, Blankstein R, Blaha MJ, Shaw LJ, Al-Mallah MH, Brackett A, Cainzos-Achirica M, Miller EJ, Nasir K. The Prognostic Value of CAC Zero Among Individuals Presenting With Chest Pain A Meta-Analysis. JACC Cardiovascular Imaging 2022, 15: 1745-1757. PMID: 36202453, DOI: 10.1016/j.jcmg.2022.03.031.Peer-Reviewed Original ResearchConceptsObstructive coronary artery diseaseAcute chest painCoronary artery calciumCoronary artery diseaseStable chest painNonobstructive coronary artery diseaseMajor adverse cardiac eventsAdverse cardiac eventsChest painCardiac eventsLow prevalenceAbsence of CACHealth care delivery modelsCare delivery modelsA Meta-AnalysisNegative predictive valueCAC assessmentArtery calciumCAC scoreIntermediate riskArtery diseaseCoronary CTACTA assessmentPrognostic valueTomography angiography