2024
Noise-aware dynamic image denoising and positron range correction for Rubidium-82 cardiac PET imaging via self-supervision
Xie H, Guo L, Velo A, Liu Z, Liu Q, Guo X, Zhou B, Chen X, Tsai Y, Miao T, Xia M, Liu Y, Armstrong I, Wang G, Carson R, Sinusas A, Liu C. Noise-aware dynamic image denoising and positron range correction for Rubidium-82 cardiac PET imaging via self-supervision. Medical Image Analysis 2024, 100: 103391. PMID: 39579623, DOI: 10.1016/j.media.2024.103391.Peer-Reviewed Original ResearchImage denoisingPositron range correctionDynamic framesSelf-supervised methodsSuperior visual qualityLow signal-to-noise ratioCardiac PET imagingDenoising methodSignal-to-noise ratioSelf-supervisionVisual qualityHigh-energy positronsRange correctionsDenoisingNoise levelImage spatial resolutionImage qualityDefect contrastPET imagingImage quantificationRadioactive isotopesPatient scansQuantitative accuracyImagesFrameExperimental Evaluation of DE-SPECT: A Hyperspectral SPECT System for Region-Selective 3-D Gamma-Ray Spectroscopy of Molecular Theragnostics
Jin Y, Zannoni E, Sankar P, Gura D, Wu R, Zhu S, Zhang F, Streicher M, Yang H, He Z, Metzler S, Liu C, Sinusas A, Meng L. Experimental Evaluation of DE-SPECT: A Hyperspectral SPECT System for Region-Selective 3-D Gamma-Ray Spectroscopy of Molecular Theragnostics. 2024, 00: 1-2. DOI: 10.1109/nss/mic/rtsd57108.2024.10657212.Peer-Reviewed Original ResearchCadmium zinc tellurideCadmium zinc telluride detectorsGamma-ray spectroscopyHigh-sensitivity imagingUniform phantomResolution phantomSPECT systemZinc telluridePhantom studyImage qualityPhantomImaging capabilitiesImaging performanceAperture systemFOVMultiple radiotracersHigh-resolutionCollimatorDual-field-of-viewPeripheral vascular diseaseDetectorState-of-the-art technologiesTellurideClinical systemsTAI-GAN: A Temporally and Anatomically Informed Generative Adversarial Network for early-to-late frame conversion in dynamic cardiac PET inter-frame motion correction
Guo X, Shi L, Chen X, Liu Q, Zhou B, Xie H, Liu Y, Palyo R, Miller E, Sinusas A, Staib L, Spottiswoode B, Liu C, Dvornek N. TAI-GAN: A Temporally and Anatomically Informed Generative Adversarial Network for early-to-late frame conversion in dynamic cardiac PET inter-frame motion correction. Medical Image Analysis 2024, 96: 103190. PMID: 38820677, PMCID: PMC11180595, DOI: 10.1016/j.media.2024.103190.Peer-Reviewed Original ResearchGenerative adversarial networkAdversarial networkMotion estimation accuracyInter-frame motionIntensity-based image registration techniqueAll-to-oneSegmentation masksImage registration techniquesOriginal frameTemporal informationDiagnosis accuracyMyocardial blood flowEstimation accuracyFrame conversionPositron emission tomographyNovel methodImage qualityPET datasetsRegistration techniqueNetworkCardiac positron emission tomographyBlood flowDynamic cardiac positron emission tomographyMotion correctionCoronary artery disease
2023
Transformer-Based Dual-Domain Network for Few-View Dedicated Cardiac SPECT Image Reconstructions
Xie H, Zhou B, Chen X, Guo X, Thorn S, Liu Y, Wang G, Sinusas A, Liu C. Transformer-Based Dual-Domain Network for Few-View Dedicated Cardiac SPECT Image Reconstructions. Lecture Notes In Computer Science 2023, 14229: 163-172. DOI: 10.1007/978-3-031-43999-5_16.Peer-Reviewed Original ResearchDual-domain networkSPECT image reconstructionImage reconstructionDeep learning methodsPrevious baseline methodsCardiac SPECT imagesHigh-quality imagesReconstruction networkIterative reconstruction processView reconstructionBaseline methodsReconstruction outputLearning methodsClinical softwareReconstruction processImaging problemsProjection dataImage qualityNetworkImagesStationary dataSPECT scannerDiagnosis of CVDLimited amountSoftwareSegmentation-Free PVC for Cardiac SPECT Using a Densely-Connected Multi-Dimensional Dynamic Network
Xie H, Liu Z, Shi L, Greco K, Chen X, Zhou B, Feher A, Stendahl J, Boutagy N, Kyriakides T, Wang G, Sinusas A, Liu C. Segmentation-Free PVC for Cardiac SPECT Using a Densely-Connected Multi-Dimensional Dynamic Network. IEEE Transactions On Medical Imaging 2023, 42: 1325-1336. PMID: 36459599, PMCID: PMC10204821, DOI: 10.1109/tmi.2022.3226604.Peer-Reviewed Original Research
2017
Fully automatic multi-atlas segmentation of CTA for partial volume correction in cardiac SPECT/CT
Liu Q, Mohy-ud-Din H, Boutagy N, Jiang M, Ren S, Stendahl J, Sinusas A, Liu C. Fully automatic multi-atlas segmentation of CTA for partial volume correction in cardiac SPECT/CT. Physics In Medicine And Biology 2017, 62: 3944-3957. PMID: 28266929, PMCID: PMC5568763, DOI: 10.1088/1361-6560/aa6520.Peer-Reviewed Original ResearchConceptsMulti-atlas segmentation methodLabel fusion methodMulti-atlas segmentationSegmentation methodConventional label fusion methodsFusion methodManual segmentationMultiple organ segmentationLabel fusion algorithmImage qualityCardiac SPECT imagesDice similarity coefficientOrgan segmentationSegmentation accuracyAutomatic segmentationCTA segmentationFusion algorithmComputed tomography angiography dataSegmentationOne-out approachCT datasetsTomography angiography dataSimilarity coefficientAngiography dataConsistent image quality
2011
Respiratory Gating for A Stationary Dedicated Cardiac SPECT System
Liu C, Chan C, Harris M, Le M, Biondi J, Volokh L, Sinusas A. Respiratory Gating for A Stationary Dedicated Cardiac SPECT System. 2011, 2898-2901. DOI: 10.1109/nssmic.2011.6152514.Peer-Reviewed Original ResearchCardiac SPECT systemDedicated cardiac SPECT systemsRespiratory motion correctionTemporal dataSlow gantry rotationData acquisitionCompressive sensorSPECT systemConventional SPECT systemImage qualityMotion correctionRespiratory gating techniquePhysical phantomRespiratory motionContrast recoveryRespiratory gatingUngated imagesImagesRespiratory triggersSystemGating techniqueMyocardial perfusion SPECTUpper abdomenLower chest
1998
A novel geometry for SPECT imaging associated with the EM-type blind deconvolution method
Liu Y, Rangarajan A, Gagnon D, Therrien M, Sinusas A, Wackers F, Zubal I. A novel geometry for SPECT imaging associated with the EM-type blind deconvolution method. IEEE Transactions On Nuclear Science 1998, 45: 2095-2101. DOI: 10.1109/23.708310.Peer-Reviewed Original ResearchBlind deconvolution algorithmImage qualityHand dataPhantom dataSPECT projectionsBlind deconvolution methodAperture projectionsDeconvolution algorithmImage resolutionAlgorithmDual-head SPECT systemParallel-hole collimatorDual-head SPECTImaging systemSystemCollimator headHole collimatorSPECT systemRestoration processImagesAperture collimatorNoise ratioCount sensitivityDataQuality
1997
A novel geometry for SPECT imaging associated with the EM-type blind deconvolution method
Liu Y, Rangarajan A, Gagnon D, Therrien M, Sinusas A, Wackers F, Zubal I. A novel geometry for SPECT imaging associated with the EM-type blind deconvolution method. 2011 IEEE Nuclear Science Symposium Conference Record 1997, 2: 1014-1017 vol.2. DOI: 10.1109/nssmic.1997.670482.Peer-Reviewed Original ResearchBlind deconvolution algorithmHigh-resolution projection imagesImage qualitySPECT imaging systemHand dataProjection imagesBlind deconvolution methodDecoding techniquesAperture projectionsImaging systemCamera headDeconvolution algorithmImage resolutionAlgorithmPhantom dataImagesSPECT projectionsParallel-hole collimatorDual-head SPECTHole collimatorSystemCollimator headRestoration processRod phantomAperture collimator