2025
Deep learning-enabled, computed-tomography-based race- and sex-specific epicardial adipose tissue thresholds for cardiovascular risk stratification
Buchwald M, Shanbhag A, Miller R, Zhang W, Michalowska A, Killekar A, Lemley M, Kavanagh P, Fujito H, Liang J, Builoff V, Knight S, Einstein A, Miller E, Feher A, Sinusas A, Chareonthaitawee P, Bullock-Palmer R, Di Carli M, Berman D, Dey D, Slomka P. Deep learning-enabled, computed-tomography-based race- and sex-specific epicardial adipose tissue thresholds for cardiovascular risk stratification. Progress In Biomedical Optics And Imaging 2025, 13410: 1341011-1341011-7. DOI: 10.1117/12.3047613.Peer-Reviewed Original ResearchEpicardial adipose tissueAmount of epicardial adipose tissueComputed tomography attenuation correctionVolume of epicardial adipose tissueSex-specific thresholdsMyocardial infarctionCardiac sizeFollow-upEAT valuesEpicardial adipose tissue densityFamily history of coronary artery diseaseHistory of coronary artery diseaseHeart sizeLeft ventricle sizeBody surface areaNonfatal myocardial infarctionBody mass indexCoronary artery diseaseRisk of deathCardiovascular risk stratificationCigarette smoking statusPrognostic valueRetrospective studyRisk stratificationVentricle size
2023
Unsupervised learning to characterize patients with known coronary artery disease undergoing myocardial perfusion imaging
Williams M, Bednarski B, Pieszko K, Miller R, Kwiecinski J, Shanbhag A, Liang J, Huang C, Sharir T, Dorbala S, Di Carli M, Einstein A, Sinusas A, Miller E, Bateman T, Fish M, Ruddy T, Acampa W, Hauser M, Kaufmann P, Dey D, Berman D, Slomka P. Unsupervised learning to characterize patients with known coronary artery disease undergoing myocardial perfusion imaging. European Journal Of Nuclear Medicine And Molecular Imaging 2023, 50: 2656-2668. PMID: 37067586, PMCID: PMC10317876, DOI: 10.1007/s00259-023-06218-z.Peer-Reviewed Original ResearchConceptsCoronary artery diseaseMyocardial perfusion imagingCause mortalityTotal perfusion deficitArtery diseaseRisk stratificationPerfusion deficitsHigher body mass indexTomography myocardial perfusion imagingMore diabetes mellitusSPECT myocardial perfusion imagingBetter risk stratificationRisk-stratify patientsBody mass indexREFINE SPECT registrySingle photon emissionDiabetes mellitusMass indexExternal cohortStress imagingMyocardial perfusionPatientsRisk phenotypePerfusion imagingImaging characteristics
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