Second Look in the Time of COVID-19
On March 25, 2020, current and recruited students and faculty ZOOMed into MD-PhD Second Look Day at maximal social-distances but minimal disruptions on meaningful conversations about "why Yale." We were so fortunate to have Dr. Akiko Iwasaki give an incredibly timely and insightful talk about the challenges facing researchers at the front lines of the COVID-19 pandemic.
Humanized Mice Lead to Breakthroughs in Blood Cancers
Humanized mice created at Yale are opening new avenues of research into cancers caused by disorders in the production of blood, such as acute myelogenous leukemia (AML) and myelodysplastic syndromes (MDS). Until recently, such research was hindered because human blood stem cells are difficult to grow in cell cultures or to engraft in mice.
From Paradox to Breakthrough
Aaron Ring, MD, PhD, was hooked by a paradox. He had been studying cytokines to understand their potential to stimulate anti-tumor immunity. Though cytokines, such as interleukin-2, have been in clinical use for decades, they have historically shown only limited effectiveness. Dr. Ring was hunting for interleukins that could deliver a specific signal to activate TILs.
Ten Years of Leadership in Immunotherapy
The last several years have been packed with revolutionary developments in immunotherapy, the decade’s biggest breakthrough in cancer treatment. Yale scientists have played leading roles in that story. Despite the tremendous progress, big challenges remain.
Two Yale Students Begin Their Professional Development as Yale Ciencia Academy Fellows
Forty young science leaders will kick off their year as fellows of the Yale Ciencia Academy (YCA) for Career Development at an in-person meeting held to coincide with the American Association for the Advancement of Science (AAAS) Annual Meeting in Seattle (February 13-17, 2020).
Richard Flavell Is Named a Distinguished Fellow by the American Association of Immunologists
Richard A. Flavell, PhD, is one of 20 scientists who have been named Distinguished Fellows by the American Association of Immunologists, which recognizes members for distinguished careers and outstanding scientific contributions, as well as their service to AAI and the immunology community. It is one of the highest honors that AAI bestows.
National Academy of Medicine Elects Six Yale Faculty Members
Six Yale School of Medicine faculty members have been elected to the National Academy of Medicine (NAM). The six are among 100 new members elected by the organization to receive the honor, which recognizes individuals who have demonstrated outstanding professional achievement and commitment to service in the fields of health and medicine.
Large Gift Establishes Colton Center for Autoimmunity at Yale School of Medicine
Philanthropists Judith and Stewart Colton have donated a major gift to establish the Colton Center for Autoimmunity at Yale, under the direction of Joseph E. Craft, MD, Paul B. Beeson Professor of Medicine and professor of immunobiology.
A Yale-Developed Drug Shows Promise as Immune Therapy for Cancer
A therapy developed by Yale Cancer Center researchers stimulates immune cells to shrink or kill tumors in mice, according to a new study published in the Journal of Experimental Medicine. The therapy is effective alone or in combination with existing cancer immunotherapies, and it appears to have lasting effects, the researchers said.
Study Explores Role of Metabolism in Immune Cell Behavior
What makes healthy cells change and become dysfunctional to the point of causing disease? In addition to a disruption in genes that regulate cells, there is another factor in cell misbehavior that involves metabolism, say Yale researchers.
Iwasaki Is Honored by the International Cytokine & Interferon Society
Akiko Iwasaki, PhD, Waldemar Von Zedtwitz Profesor of Immunobiology and Molecular, Cellular, and Developmental Biology; and professor of dermatology, is a 2019 recipient of the Seymour & Vivian Milstein Award for Excellence in Interferon and Cytokine Research, given by the International Cytokine & Interferon Society (ICIS).