Study Explores Role of Metabolism in Immune Cell Behavior
What makes healthy cells change and become dysfunctional to the point of causing disease? In addition to a disruption in genes that regulate cells, there is another factor in cell misbehavior that involves metabolism, say Yale researchers.
Study points to potential personalized approach to treating lupus
In individuals with lupus, immune cells attack the body’s own tissue and organs as if they are enemy invaders. A new Yale-led study describes how a protein found in common bacteria triggers that auto-immune response. The finding opens the door to future therapies targeting the bacteria rather than the immune system, the researchers said.
Five young Yale scientists recognized for excellence
Five Yale faculty members are among the 84 young researchers designated as Faculty Scholars under a new program to promote early career scientists, launched by the Howard Hughes Medical Institute, the Simons Foundation, and the Bill and Melinda Gates Foundation.
CaSB@Yale launches with $9.5M federal grant to battle deadliest cancers
Yale University researchers across a spectrum of disciplines are coming together to fight some of the deadliest forms of cancer with a novel approach that has gained support from the National Cancer Institute (NCI) of the National Institutes of Health (NIH).
Colón-Ramos named McConnell Duberg Associate Professor
Daniel A. Colón-Ramos, PhD, recently appointed as Dorys McConnell Duberg Associate Professor of Neuroscience and Cell Biology, focuses his research on how synapses are formed and maintained to control behavior and store memories. Colón-Ramos’ discoveries have altered long-held views on the process and may offer important clues in the fight against disease.
Protein-slaying Drugs Could Be the Next Blockbuster Therapies
A drug strategy called targeted protein degradation; and pursued by Craig Crews, PhD, Lewis B. Cullman Professor of Molecular, Cellular, and Developmental Biology, and professor of chemistry; capitalizes on the cell’s natural system for clearing unwanted or damaged proteins, and is in line to be used in promising clinical trials.
Of Worms and a Special Love of Home
Daniel Colón-Ramos works with the roundworm C. elegans as a means of advancing knowledge of the fundamental building blocks of the nervous system, saying that mastering the basics is essential to answering the bigger questions. He also has dedicated himself to improving opportunities for people in his native Puerto Rico.
Ponce receives Paul Nelson Award from Council of Chairs of Training Councils
Allison Ponce, PhD, Associate Professor of Psychiatry, has received the Paul Nelson Award from the Council of Chairs of Training Councils (CCTC). CCTC is comprised of the presidents and chairs of the education and training associations in health service psychology with the mission of enhancing collaboration in psychology education.
Scientists find clues to mystery of Williams Syndrome’s peculiar symptoms
Patients with Williams Syndrome often are extremely social and possess a remarkable affinity and talent for music. They also experience life-threatening cardiovascular problems and developmental disabilities. The mystery is what happens during development to cause such peculiar symptoms.
Neuroscientists, Geneticist Win ‘High Risk, High Reward’ Grants
Three Yale researchers have won 2018 ‘High Risk, High Rewards’ grants from the Common Fund of the National Institutes of Health, which intends to fund “major opportunities and gaps in biomedical research that require trans-NIH collaboration to succeed.”