CELLO Study to Explore Early Treatment of Multiple Sclerosis
Yale University announced today the initiation of a multicenter study aimed at treating early stage multiple sclerosis (MS). Supported by and in collaboration with Genentech, a member of the Roche Group, the study, known as “CELLO,” will investigate whether short-term treatment with ocrelizumab in patients with MRI lesions consistent with early MS without clinical disease—known as radiologic isolated syndrome—prevents the onset of symptoms.
Yale Neurologists Identify Consistent Neuroinflammatory Response in ICH Patients
According to a recent study published in "Science Immunology," A team of researchers from Yale and MIT partnernered with a large clinical trial of minimally-invasive surgery to tackle defining the human neuroinflammatory response in living patients suffering from intracerebral hemorrhage.
Dr. David Hafler Elected to the Association of American Physicians
David Hafler, MD, FANA, William S. and Lois Stiles Edgerly Professor of Neurology and Professor of Immunobiology; Chair, Department of Neurology; Neurologist-in-Chief, Yale New Haven Hospital has been elected to the Association of American Physicians (AAP).
$11.12M gift supporting hemorrhagic stroke treatment launches innovative research network
Research teams from Massachusetts General Hospital, Yale University and University of California, San Francisco form the American Heart Association’s newest stroke scientific research network funded by Henrietta B. and Frederick H. Bugher FoundationSource: American Heart Association
Dr. David Hafler Conducts APSA Webinar
David Hafler MD recently served on the panel of a webinar led by the American Physician Scientists Association (APSA). The webinar presented strategies to support early-career residents, fellows, and junior faculty, as well as insights into how this group is affected by the COVID-19 pandemic.
Yale IBIO investigators link tolerance defects to pathogenic autoantibody production
A team led by IBIO faculty members, Eric Meffre and Kevin O’Connor, explored both B cell tolerance and the origins of pathogenic autoantibodies in neuromyelitis optica (NMO), a severe autoimmune neurological disease that primarily affects young women.
Hafler Is Elected to the National Academy of Medicine
David A. Hafler, MD, chair of the Department of Neurology, the William S. and Lois Stiles Edgerly Professor of Neurology, and professor of immunobiology, has been elected to the National Academy of Medicine, in recognition of his outstanding achievements in medicine.
Macrophages need two signals to begin healing process
In the immune system, macrophages act not only as soldiers responding to invading pathogens but also help rebuild the injured tissue once the infection is defeated. A new study by Yale School of Medicine researchers published in the journal Science show how they accomplish this seemingly unrelated task.
Immune system surprise hints at new strategy for fighting HIV
The discovery of the innate immunity system’s role in mobilizing the body’s defenses against invading microorganisms has been long studied at Yale. Now in the Nov. 17 issue of the journal Nature Immunology, Yale researchers led by Margarita Dominguez-Villar and David Hafler have discovered a surprising twist to the story that may open a new avenue in the fight against HIV.
AAN 2021 Virtual Annual Meeting: Highlights
Each year, the American Academy of Neurology (AAN) hosts a meeting wherein neurologists nationwide convene to present on their latest research findings and to learn from their peers. The following members of Yale Neurology presented abstracts at the 2021 virtual annual meeting:
PATHS helps students from underrepresented backgrounds realize med school dreams
Nelson Perez Catalan discovered he was interested in pursuing science while working at a student job at the University of Oregon cleaning glass in the labs. He found himself drawn to research around the brain, and thought about pursuing an MD/PhD, but there was no medical school at his university and as a transplant from Chile, he says much of the U.S. college process was mystifying to him. Then he learned about PATHS, or Program to Advance Training in Health and Sciences at Yale School of Medicine.