2009
Structure of the RAG1 nonamer binding domain with DNA reveals a dimer that mediates DNA synapsis
Yin FF, Bailey S, Innis CA, Ciubotaru M, Kamtekar S, Steitz TA, Schatz DG. Structure of the RAG1 nonamer binding domain with DNA reveals a dimer that mediates DNA synapsis. Nature Structural & Molecular Biology 2009, 16: 499-508. PMID: 19396172, PMCID: PMC2715281, DOI: 10.1038/nsmb.1593.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid MotifsAmino Acid SequenceAnimalsBase SequenceChromosome PairingCrystallography, X-RayDNAFluorescence Resonance Energy TransferHomeodomain ProteinsMiceModels, MolecularMolecular Sequence DataNucleic Acid ConformationProtein MultimerizationProtein Structure, QuaternaryProtein Structure, TertiarySolutionsStatic Electricity
2004
Cloning of Apoptosis-Related Genes by Representational Difference Analysis of cDNA
Hubank M, Bryntesson F, Regan J, Schatz DG. Cloning of Apoptosis-Related Genes by Representational Difference Analysis of cDNA. Methods In Molecular Biology 2004, 282: 255-273. PMID: 15105570, DOI: 10.1385/1-59259-812-9:255.Peer-Reviewed Original ResearchConceptsRepresentational difference analysisApoptosis-related genesComplementary DNA representational difference analysisCDNA-RDAGene expressionDifferential gene expression analysisIdentification of genesKey target genesExpression levelsGene expression analysisLow-abundance transcriptsGene microarray analysisModel organismsTranscriptional differencesTarget genesExpression analysisDifferential displayMicroarray analysisGene microarrayCDNA fragmentsCDNA ampliconsGenesBase pairsSerial analysisPolymerase chain reaction amplification
1996
Initiation of V(D)J recombination in vitro obeying the 12/23 rule
Eastman Q, Leu T, Schatz D. Initiation of V(D)J recombination in vitro obeying the 12/23 rule. Nature 1996, 380: 85-88. PMID: 8598914, DOI: 10.1038/380085a0.Peer-Reviewed Original Research