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Mechanical forces impact immune response in the lungs By Ziba Kashef August 21, 2019 Share this with Facebook Share this with Twitter Share this with LinkedIn Share this with Email Print this 3d rendered medically accurate illustration of a mans lung (© stock.adobe.com) When the body is fending off an infection, there are changes in temperature, pH balance, and metabolism. Yale researchers wondered if yet other factors might come into play, and in a recent study, confirmed that mechanical forces also influence the immune response.

Carla Vanina Rothlin, PhD, newly named as Dorys McConnell Duberg Professor of Immunobiology, studies the mechanisms that regulate the magnitude and resolution of the immune response. Rothlin is also a professor of pharmacology, a member of the Yale Cancer Center, and a Howard Hughes Faculty Scholar.

Kevan Herold, MD, newly named as C.N.H. Long Professor of Immunobiology and of Medicine, conducts research on the basis for autoimmune diseases and develops new therapies based on these studies. His focus has largely been in the field of autoimmune Type 1 diabetes.

JAX allergy research might lead to new treatments

An unexpected source drives the molecule behind severe allergies, reports a team of researchers in today’s issue of Science. Their findings may point to a new way to prevent or reduce life-threatening allergic reactions.

For millions of Americans, contact with certain foods can cause anaphylaxis, a life-threatening allergic reaction. A new study has uncovered a previously unknown cell type that promotes the reaction and could be used to identify individuals who are most at risk.

Yale investigators have shown that the combination of a vaccine and a medicated cream is a promising strategy to dramatically reduce the recurrence of genital herpes.