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Massive, repetitive stretches of DNA in the human genome may harbor hints about the onset of a rare, inherited neurodegenerative disorder called ataxia-telangiectasia as well as other related diseases, a new Yale School of Medicine study finds.

Marie Robert, MD, Professor of Pathology and of Medicine (Digestive Diseases), and Jordan Pober, MD, PhD, the Bayer Professor of Translational Medicine and Professor of Immunobiology, Pathology, and Dermatology, have been awarded a grant from the Program for the Promotion of Interdisciplinary Team Science (POINTS) at Yale School of Medicine to study the Pathogenesis of Celiac Disease.

Unlike jabs, nasal vaccines target the respiratory tract, the body’s first line of defence against infection

Chronic inflammation, one of the major hallmarks of aging, is thought to be partly caused by senescent cells that may accumulate in older individuals. Now, Yale researchers have received a grant from the National Institutes of Health (NIH) Common Fund’s Cellular Senescence Network Program (SenNet) to study these specialized cells.

There are multiple pathways for advanced research training in cardiovascular medicine.

In a new study, Yale researchers show that moderate calorie restriction in people reduces the production of a protein called SPARC, which then reins in harmful inflammation and improves health in the aged. It could be a target for extending human health span, they report.

While the risks of deaths and hospitalizations from Covid-19 are substantially lower now, navigating this phase of the pandemic can be frustrating and confusing.

Discoveries & Impact highlights select scientific discoveries per section across Yale's Department of Internal Medicine...

Yale research suggests that several neurodegerative diseases may originate not in the nervous system, but in the gut microbiome.