Research & Publications
My laboratory focuses on the molecular characterization of human chromosome abnormalities. Molecular methods such as fluorescence in situ hybridization (FISH) mapping using YAC or BAC clones, microsatellite allelotyping, and sequencing analysis of SNP variants and gene mutations have been used. We are initiating high through-put chromosome-specific and genome-wide array-based analysis for mapping segmental deletions/duplication and sequencing rearrangement breakpoints. The goals of this laboratory are to identify disease-causing genes or genetic markers of diagnostic and prognostic values, and to dissect underlying molecular mechanisms.
Education & Training
- PhDUniversity of Alabama at Birmingham (1996)
- Postdoc Fellow, Clinical CytogeneticsYale School of Medicine
- Postdoc Fellow, Clinical Molecular GeneticsUniversity of Alabama at Birmingham