2003
Selective immmunotherapy through extracorporeal photochemotherapy: yesterday, today, and tomorrow
Girardi M, Knobler R, Edelson R. Selective immmunotherapy through extracorporeal photochemotherapy: yesterday, today, and tomorrow. Hematology/Oncology Clinics Of North America 2003, 17: 1391-1403. PMID: 14710891, DOI: 10.1016/s0889-8588(03)00106-0.Peer-Reviewed Original ResearchConceptsLow side effect profileSide effect profilePotential novel strategyMechanism of actionImmunosuppressive medicationsExtracorporeal photochemotherapyEffect profileTransplant rejectionTreatment of cancerClinical recordsRole of ECPClinical studiesT cellsTreatment considerationsModern therapeuticsTreatmentNovel strategyGVHDMedicationsAutoimmunityCTCLMalignancyECPTherapyCancer
2001
Extracorporeal Photochemoimmunotherapy in Cutaneous T Cell Lymphomas
KNOBLER R, GIRARDI M. Extracorporeal Photochemoimmunotherapy in Cutaneous T Cell Lymphomas. Annals Of The New York Academy Of Sciences 2001, 941: 123-138. PMID: 11594566, DOI: 10.1111/j.1749-6632.2001.tb03716.x.Peer-Reviewed Original ResearchConceptsCutaneous T-cell lymphomaT cell clonesAutoreactive T cell clonesT-cell lymphomaCell clonesCell lymphomaDisease-causing T cellsPathogenic T cell clonesT cell-mediated disordersClass I Major Histocompatibility Complex PresentationClonotypic T cell receptorCell-mediated disordersTumor-specific antigensMajor histocompatibility complex presentationT cell receptorTypes of cancerUnique antigenic determinantsECP efficacyHost diseaseAllograft rejectionConversion of monocytesSelective immunotherapyClinical trialsFunctional DCsDendritic antigen
2000
Cutaneous T-cell lymphoma: pathogenesis and treatment.
Girardi M, Edelson RL. Cutaneous T-cell lymphoma: pathogenesis and treatment. Oncology 2000, 14: 1061-70; discussion 1070-4, 1076. PMID: 10929591.Peer-Reviewed Original ResearchConceptsCutaneous T-cell lymphomaSkin immune systemImmune systemT cellsManagement of CTCLCutaneous T-cellMemory T cellsT helper cellsT-cell lymphomaSelective adhesion moleculeLymph nodesClinical spectrumPeripheral bloodCutaneous pathogensMajor subtypesPathogenesisAdhesion moleculesLymphomaDistinctive subsetTreatmentNormal functioningCellsBetter understandingImmunosurveillanceMalignancy