2019
Association Between Diaphragmatic Paralysis and Ipsilateral Cervical Spondylosis on MRI
O’Beirne S, Chazen JL, Cornman-Homonoff J, Carey BT, Gelbman BD. Association Between Diaphragmatic Paralysis and Ipsilateral Cervical Spondylosis on MRI. Lung 2019, 197: 727-733. PMID: 31535202, DOI: 10.1007/s00408-019-00271-y.Peer-Reviewed Original ResearchConceptsCervical spine magnetic resonance imagingMagnetic resonance imagingSpine magnetic resonance imagingCervical spondylosisCervical spineUnderrecognized causeContralateral foraminal stenosisCervical spine levelsDiaphragmatic paralysisDiaphragmatic dysfunctionNeuroforaminal stenosisTotal cohortForaminal stenosisRetrospective studyUnderlying etiologySpine levelImportant causeOverall severityResonance imagingEtiologySeveritySpineSpondylosisStenosisC4-C5
2012
Evaluation of common genetic variants in 82 candidate genes as risk factors for neural tube defects
Pangilinan F, Molloy AM, Mills JL, Troendle JF, Parle-McDermott A, Signore C, O’Leary V, Chines P, Seay JM, Geiler-Samerotte K, Mitchell A, VanderMeer JE, Krebs KM, Sanchez A, Cornman-Homonoff J, Stone N, Conley M, Kirke PN, Shane B, Scott JM, Brody LC. Evaluation of common genetic variants in 82 candidate genes as risk factors for neural tube defects. BMC Medical Genomics 2012, 13: 62. PMID: 22856873, PMCID: PMC3458983, DOI: 10.1186/1471-2350-13-62.Peer-Reviewed Original ResearchConceptsStrongest association signalAssociation signalsCandidate genesNTD mouse modelsSingle strong signalHigh-priority candidatesCommon genetic variantsMaternal periconceptional folic acid supplementationNTD riskGenetic association studiesCommon birth defectsPathway genesList of variantsB12 pathwayFolate metabolic pathwayAssociation studiesMaternal effectsMetabolic pathwaysGenesPriority candidatesGenetic variantsCommon variationTube defectsCandidate polymorphismsSNPs