WEBVTT

NOTE duration: "00:07:51.765"


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Is Frances Lopez. And as

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Tania mentioned, I'll be talking

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about the Yale Center for

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Genome Analysis.

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And I'm gonna start directly

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with,

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what I oops. What I

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consider the most important slide,

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which is the summary of

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the things we do or

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we offer at the at

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the genome center. As a

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genome center, you can imagine,

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we offer any kind of

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solutions regarding next generation sequencing,

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but we also work with

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the,

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microarrays just for genotyping and

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transcriptomics.

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We also keep up with

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the cutting edge technologies

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in single cell and in

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special omics,

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for including multi omics profiling

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and transcriptomics.

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We provide bioinformatics

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support,

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free of charge

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and, grant support too. And

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I like to think about

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this bioinformatics support being end

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to end, so from experimental

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design to publication

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support.

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We also keep,

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doing r and d, offering

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new services, as much as

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we can. And often, this

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is through collaboration with the

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Arkansas Center Investigations.

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And one thing that is

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often forgotten is we offer

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consultation,

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and that is always free.

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So don't hesitate to contact

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us if you have,

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you know, if you have

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questions about the experimental design

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or what type of platform

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would be better for your

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needs to answer your questions.

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Just a brief introduction to

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the center. The center was

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established in two thousand nine.

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The director is doctor Zreken

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Manet.

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We are also at West

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Campus. You can find us

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at eight hundred thirty West

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Campus Drive.

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We have a bigger space

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of lot, and it's really

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beautiful.

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There are thirty five people

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working in there, including the

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bioinformaticians.

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If if you have the

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chance, we invite you to

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stop by and give a

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look, and we'll show you

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around.

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We also have,

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a computer HPC,

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a space dedicated only to

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the data that we produce.

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And

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so if you sequence with

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us, you would have you

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would have access to the

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high performance computing dedicated space,

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storage,

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and compute power for your

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analysis.

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We provide a a quite

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a big range of sequencing

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machines.

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Our main workforce

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is the NovaSeq x plus,

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the IlluminaSeq

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x plus, but we also

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offer,

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other alternative, including the LMAN

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Bioscience,

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the ABT.

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If you if you need,

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longer reads with, more higher

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acuity compared with,

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the Illumina machines, we also

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provide the,

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long read, you know, the

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third generation of sequencers,

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that that provide real time

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sequencing

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and kilobases of, reads, like

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the back bio and the

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nano nano pore meaning.

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So we can use,

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we off we use those

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machines with different,

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services. Here, I'm just listing

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probably, the most popular ones,

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but it goes from DNA

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sequencing, whole exome sequencing, whole

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genome sequencing,

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including FFPE tissues,

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for transcriptomics,

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epigenetics,

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ataxic,

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methylation sequencing.

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And, also, we work with

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different type of samples, including

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cell free DNA or even,

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dark blood spots.

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In the past ten years,

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as you probably know, single

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cell platforms are be becoming

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really popular.

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We we offer different alternative,

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including

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including,

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the single cell that

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we recently incorporated.

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But ten x has still

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been the most popular one.

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But don't forget, we also

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offer probably what could be

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alternative

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alternative options,

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could be cheaper like parts

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bioscience

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or the Illumina single cell,

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kits.

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And as I mentioned, we

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like to keep up with

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the cutting edge technologies, including

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the special omics technologies.

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We like to divide it

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into big categories. The ones

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are image based platforms

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that give you a subcellular

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resolution.

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The problem is only based

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for human and mouse, but

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we also offer, sequencing based

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platforms

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on organism agnostics, including the

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Curio

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and the ten x and

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HD. And we also offer

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platforms for special,

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epigenetics.

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And even more recently, we

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have incorporated,

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proteomics in our services.

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We have two main ones,

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which is the all in

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00:04:40.354 --> 00:04:40.854
reveal

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that allows you to measure

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over a thousand,

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proteins.

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And this is based on,

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immunoassays

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and the readouts that we

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use in next generation sequencing.

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00:04:50.970 --> 00:04:52.089
And in the future, we're

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applying to incorporate a new,

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equipment, which is the Allyn

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signature

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that would allow us to

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offer more,

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00:04:58.885 --> 00:05:00.964
panels for, protein analysis using

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the ALYN technology.

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We also offer the Bruker

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00:05:04.325 --> 00:05:04.825
IsoSpark,

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which is an ELISA based

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00:05:08.005 --> 00:05:08.505
immunoassays,

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to profile the cytokines.

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We've been working hard also

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to facilitate the access,

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and tracking of the samples.

NOTE Confidence: 0.999163

00:05:21.360 --> 00:05:22.180
We created

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an iLab portal,

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where users can create accounts

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and track their samples through

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the process of sequencing.

NOTE Confidence: 0.9346191

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So if you you have

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the first time contacting us,

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you need to contact Chris

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00:05:35.315 --> 00:05:35.815
Castaldi

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to create an account in

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iLab. And after that, if

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00:05:38.755 --> 00:05:39.555
you need to send us

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00:05:39.555 --> 00:05:41.380
the samples, we have different

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00:05:41.380 --> 00:05:42.660
methods. You can come directly

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to the genome center or

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you can ship it to

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the genome center, but we

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also have two drop off

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locations

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in George, George Street, three

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00:05:50.420 --> 00:05:52.600
hundred George Street and Tuck

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Building.

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00:05:54.875 --> 00:05:55.855
And as I mentioned,

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we also provide,

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bioinformatics services.

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And in this case, it's

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me, the contact person.

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00:06:03.115 --> 00:06:04.395
I like to divide the

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00:06:04.395 --> 00:06:06.075
bioinformatics service in three big

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00:06:06.075 --> 00:06:07.275
areas. Of course, the main

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00:06:07.275 --> 00:06:08.015
one is

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to provide free data analysis

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00:06:10.380 --> 00:06:10.880
services,

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from design to publication,

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00:06:15.020 --> 00:06:15.520
support.

NOTE Confidence: 0.998291

00:06:17.020 --> 00:06:18.480
We also provide training.

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00:06:18.940 --> 00:06:19.839
We do workshops

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and seminars through the year.

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And, again oops.

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One thing that it's often

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forgotten

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is that,

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we also facilitate

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access to the technologies through

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pipelines. So we create pipelines

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that are accessible,

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in Macquarie,

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our HPC.

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And if any of those

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needs, they don't ended up

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following or they don't fit,

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your needs, we also have

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a bioinformatics teams that we

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can find other alternatives for

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you.

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Everything that I mentioned in

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this presentation is also available

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in our website. We try

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to keep it updated

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as much as we can,

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and you also have pricing

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in there about all the,

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services that we provide.

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And please don't hesitate to

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contact us at y c

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e a, IDL dot e

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d u. We have people

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monitoring that address.

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But if you have specific

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questions,

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for specific areas,

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probably this is the most

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important people that you need

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to know about it.

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We have.

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We have questions about genomics

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or any kind of the

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long read sequencing technologies.

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Irena can help you with,

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whole genomes and whole sequencing

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captures,

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ChIP seq or FFPP,

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sample manipulations.

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Chris Castaldi can help you

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with, as I mentioned, with

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the AI live accounts, but

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also with the transcriptomic.

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And myself,

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I'm the contact person for

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any kind of bioinformatic names,

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you may

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have. And that's it.