Neurology Grand Rounds

Carolyn Fredericks, MD studied classics and neuroscience at Brown, then completed her medical training at Stanford, Johns Hopkins, and UCSF, culminating in a behavioral neurology fellowship at the UCSF Memory & Aging Center. There, she gained research experience in advanced neuroimaging in dementia and exposure to patients with a wide variety of cognitive and behavioral concerns, including less common dementia syndromes. She joined the faculty at Yale in Fall 2019, where she has established The Fredericks Lab, focused on understanding why some individuals are at greater risk of dementia, and how diseases including Alzheimer’s and dementia with Lewy bodies progress through functional networks in the brain. The lab uses multimodal neuroimaging, deep clinical phenotyping, and blood-based biomarkers to answer these questions. Fredericks is a member of Yale’s Clinical Neuroscience Imaging Center (CNIC), a multidisciplinary group applying innovative imaging methods to the study of brain disease. Clinically, Dr. Fredericks specializes in the diagnosis and treatment of neurodegenerative disorders, with an emphasis on clinically heterogeneous forms of Alzheimer’s disease, alpha-synucleinopathy, frontotemporal lobar degeneration, and others.