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DTSTART:20241103T020000
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DESCRIPTION:Abstract: Little empirical guidance exists for planning adequa
 tely powered functional neuroimaging studies. An underappreciated barrier
  is that commonly reported effect sizes across the brain do not account f
 or sampling error\, inflating expectations. In this talk we introduce a m
 eta-analytic variance decomposition method that accounts for sampling err
 or to estimate the true mass univariate distribution of effects and estab
 lish benchmarks in a mega-analysis of 63 studies across seven datasets (5
 2\,979 participants). We discuss how small effects across the brain can b
 e improved with multivariate and task-based analyses\, that studies plann
 ed using uncorrected effects are typically half as powerful as expected\,
  and how this work lays the groundwork for more empirically informed powe
 r analyses and study planning in fMRI. Bio: Dr. Stephanie Noble is an Ass
 istant Professor in the Department of Psychology\, Department of Bioengin
 eering\, and Center for Cognitive and Brain Health at Northeastern Univer
 sity\, where she directs the NeuroPRISM lab. She received her BS in Chemi
 cal & Biological Engineering from Princeton\, her PhD in the Interdepartm
 ental Neuroscience Program at Yale\, and postdoctoral training in Radiolo
 gy & Biomedical Imaging at Yale\, in addition to entrepreneurship experie
 nces outside academia. Her lab develops tools for more precise neuroimagi
 ng statistical inference and prediction\, with the goal of improving repr
 oducibility and enabling personalized predictions of disease and developm
 ent. Her work has appeared in venues including PNAS and Neuron\, received
  support from the NSF and NIH\, and was recently recognized with a 2026 N
 IH Rigor Champions Award.\n\nSpeaker:\nStephanie Noble\n\nAdmission:\nFre
 e\n\nFood:\nCoffee\, Snacks\, Tea\n\nDetails URL:\nhttps://medicine.yale.
 edu/event/ybii-advances-in-biomedical-imaging-seminar-series-stephanie-no
 ble-phd/\n
DTEND;TZID=America/New_York:20260910T140000
DTSTAMP:20261001T222816Z
DTSTART;TZID=America/New_York:20260910T130000
GEO:41.301420;-72.933837
LOCATION:The Anlyan Center\, N203\, 300 Cedar Street\, New Haven\, CT\, Un
 ited States
SEQUENCE:0
STATUS:Confirmed
SUMMARY:YBII Advances in Biomedical Imaging Seminar Series - Stephanie Nob
 le\, PhD
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