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DTSTART:20241103T020000
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DESCRIPTION:Bio : Dr. Chuan Huang is an Associate Professor of Radiology a
 nd Imaging Sciences and the Director of PET-MRI Research at Emory Univers
 ity School of Medicine. He was named a Distinguished Investigator by the 
 Academy for Radiology & Biomedical Imaging Research in 2023. Dr. Huang's 
 research focuses on PET/MR and its broader clinical and translational app
 lications. He has authored over 80 publications. Prior to joining Emory i
 n November 2022\, he was a tenured Associate Professor of Radiology and P
 sychiatry at the State University of New York at Stony Brook. He complete
 d his postdoctoral training at Massachusetts General Hospital and Harvard
  Medical School in 2014\, where he was subsequently promoted to Instructo
 r. He previously served as Chair of the ISMRM PET/MR Study Group and was 
 a member of the organizing committee for the 2023 SNMMI-ISMRM co-sponsore
 d PET/MR Workshop. He currently serves on the committee of the ISMRM MR i
 n Psychiatry Study Group. Abstract : The glymphatic-associated pathway is
  increasingly recognized as a key mechanism for cerebrospinal fluid (CSF)
 -mediated solute clearance\, with growing relevance to aging and neurodeg
 enerative disease. Yet\, imaging this pathway in humans remains challengi
 ng due to its slow and spatially heterogeneous dynamics. In this presenta
 tion\, I will outline a multimodal imaging strategy combining PET and MRI
  to improve the characterization and clinical applicability of glymphatic
 -associated CSF transport metrics. I will first review limitations of cur
 rent MRI-based approaches - including phase-contrast MRI\, diffusion-weig
 hted imaging (DWI)\, and diffusion tensor imaging along the perivascular 
 space (DTI-ALPS) -which primarily infer fluid dynamics indirectly and may
  be confounded by other microstructural factors. In contrast\, PET imagin
 g enables time-resolved quantification of solute washout\, offering a win
 dow into net CSF clearance kinetics. I will highlight our recent work app
 lying dynamic 18F-FDG PET to measure ventricular CSF clearance. Together\
 , these tools offer a more integrated and physiologically grounded framew
 ork for studying glymphatic-associated dysfunction in human disease.\n\nS
 peaker:\nChuan Huang\n\nAdmission:\nFree\n\nFood:\nSnacks\, Tea: Cookies\
 , coffee and tea will be provided.\n\nDetails URL:\nhttps://medicine.yale
 .edu/event/bis-scientific-pet-mri-glymphatic-fluid-dynamics/\n
DTEND;TZID=America/New_York:20260317T150000
DTSTAMP:20260427T144157Z
DTSTART;TZID=America/New_York:20260317T140000
LOCATION:Email contact for zoom link password\, URL: https://yale.zoom.us/
 j/93954346443
SEQUENCE:0
STATUS:Confirmed
SUMMARY:BIS Seminar
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