Long-Term Outcomes of Childhood-Onset Epilepsy

We are engaged in a longitudinal study of children with newly diagnosed epilepsy, started in 1993. The first phase of the study concerned the prediction of remission, relapse, and intractability early in the course of the disorder. We have addressed several issues concerning the mid-term (5-10 years) seizure outcomes, mortality, status epilepticus, developmental and educational outcomes. We hope to provide information regarding: occurrence of later-appearing intractable epilepsy and the association with hippocampal volumetric measurements. We recently published a paper on the social, educational, behavioral, psychiatric and quality of life outcomes in young adults with childhood onset epilepsy related to seizure outcome. This information will be central to informing evaluation, treatment, management, and counseling approaches for children with epilepsy and their families.

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Additional Links: Connecticut Study of Epilepsy.