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Sidi Chen, PhD

Associate Professor

Contact Information

Sidi Chen, PhD

Lab Location

Mailing Address

  • Genetics

    850 West Campus Drive, Integrated Science & Technology Center

    West Haven, CT, 06516

    United States



Sidi Chen joined the Yale Faculty in 2015 as an assistant professor in the Department of Genetics and Systems Biology Institute, also as a member of the Yale Cancer Center and the Yale Stem Cell Center. Chen earned a PhD in evolutionary genetics from The University of Chicago with an award-winning dissertation with Dr. Manyuan Long. After graduation he performed postdoctoral studies at MIT under the mentorship of Dr. Phil Sharp, and also the Broad Institute working with Dr. Feng Zhang. His research focuses on providing a global understanding of biological systems. Chen developed and applied genome editing and high-throughput screening technologies, precision CRISPR-based in vivo models of cancer, global mapping of functional drivers of cancer oncogenesis and metastasis. More recently, he developed novel systems that enable rapid identification of novel immunotherapy targets and new modalities of cancer immunotherapy. Dr. Chen received a number of national and international awards including the DoD Era of Hope Scholar Award, NIH Director’s New Innovator Award, Blavatnik Innovator, Damon Runyon Cancer Research Fellow, Dale Frey Award for Breakthrough Scientists, AACR NextGen Award for Transformative Cancer Research, TMKF Innovative/Translation Cancer Research Award, BCA Exceptional Research Grant Award, MRA Young Investigator Award, V Scholar, Bohmfalk Scholar, Ludwig Family Foundation Award, St. Baldrick’s Foundation Award, CRI Clinic & Laboratory Integration Program (CLIP), MIT TechReview Regional 35 Innovators, and Sontag Foundation Distinguished Scientist Award.

Education & Training

  • Visiting Postdoc
    Broad Institute of MIT and Harvard (2015)
  • Postdoctoral Fellow
    MIT (2015)
  • PhD
    The University of Chicago (2011)
  • Visiting Student
    Stanford University (2009)

Honors & Recognition

AwardAwarding OrganizationDate
DoD Era of Hope Scholar AwardDoD BCRP2020
Yale Cancer Center Basic Science Research PrizeYale Cancer Center2020
Blavatnik Innovator AwardYale University Blavatnik Fund2019
Distinguished Scientist AwardSontag Foundation2018
NIH Director's New Innovator Award (DP2)NIH OD / NCI2018
Ludwig Family Foundation2018
Bohmfalk Scholar in Medical Research2017
LCRP Idea Development AwardDepartment of Defense2017
AACR NextGen Award for Transformative Cancer ResearchAACR2017
Exceptional Research Grant AwardBreast Cancer Alliance2017
St. Baldrick’s Foundation Award2016
Young Investigator AwardMelanoma Research Alliance2016
Dale Frey Award for Breakthrough ScientistsDamon Runyon Cancer Research Foundation2015
Damon Runyon Cancer Research FellowshipDamon Runyon Cancer Research Foundation2012
Best Dissertation AwardThe University of Chicago2011
Chair’s Special Award, Best PresentationGordon Research Conference2011
National Science Foundation Doctoral Dissertation Improvement GrantNational Science Foundation2010
Chun-Tsung ScholarTsung-Dao Lee Foundation2002

Departments & Organizations