Yale Radiology and Psychiatry Researchers Join with Penn Medicine to Create a New Center to Study Opioid Use Disorders
Opioid use disorder has reached epidemic levels in the United States. Over the last two decades, opioid-related overdose deaths increased by more than 50 percent, with nearly 50,000 in 2018, according to the Centers for Disease Control and Prevention. Researchers from Yale School of Medicine (YSM) and Penn Medicine, which comprises the Perelman School of Medicine at the University of Pennsylvania, have created a new center that focuses on neuroimaging to improve our understanding of opioid use disorders and find new treatments.
Funding will further study of bipolar disorder in adolescence
The International Bipolar Foundation (IBPF) will fund a project exploring the development of bipolar disorder in adolescence led by Hilary Blumberg, MD, associate professor of psychiatry, in the Child Study Center and of diagnostic radiology. Blumberg is the director of the Mood Disorders Research Program at Yale.
Addicts’ cravings have different roots in men and women
A new brain imaging study by Yale School of Medicine researchers suggests stress robustly activates areas of the brain associated with craving in cocaine-dependent women, while drug cues activate similar brain regions in cocaine-dependent men. The study, expected to be published online Jan. 31 in the American Journal of Psychiatry, suggests men and women with cocaine dependence might benefit more from different treatment options.
Rhee: Trends in Co-Prescribing of Opioids and Opioid Potentiators Among U.S. Adults, 2007–2018
Lead author Greg Rhee, PhD, Assistant Professor Adjunct in the Department of Psychiatry, explores trends in co-prescribing opioids and opioid potentiators among U.S. adults in a recent article published in the American Journal of Preventive Medicine.Source: American Journal of Preventive Medicine
Treatment with Genetically Altered Viruses Targets and Destroys Ovarian Cancer in Mice
Researchers have successfully eliminated chemotherapy-resistant ovarian cancer cells in mice using a single injection of two viruses genetically combined and altered to be safe, leading to long-term survival and demonstrating a potential breakthrough treatment for women.
Systematic Review of Racial Disparities in Clozapine Prescribing
J. Corey Williams, MD, a graduate of the Yale Psychiatry Residency Program, collaborated with Cenk Tek, MD, Associate Professor of Psychiatry and Vinod Srihari, MD, Professor of Psychiatry to conduct a systematic review of published evidence on clozapine prescribing disparities across racial and ethnic categories.Source: Schizophrenia Research
Narrow-spectrum antibiotics viable treatment option for acne
Perceptions of antibiotics and potential antibiotic resistance have caused some physicians to be wary of the drug class when prescribing an acne treatment regimen. However, narrow-spectrum antibiotics have shown a low propensity for development of antimicrobial resistance while also effectively treating acne.Source: Dermatology Times
Clearing the Haze: What Do We Still Need to Learn About Electronic Nicotine Delivery Systems?
Important questions remain regarding the relative benefits versus risks of electronic nicotine delivery systems (ENDS). In light of these challenges, the authors propose key ENDS research priorities to address these gaps.Source: Cancer Prevention Research
Yale Study: Diaper Need is Associated with Pediatric Care Utilization
Kunmi Sobowale, MD; Ashley Clayton, MA; and Megan Smith, DrPH, MPH, co-authored a paper in The Journal of Pediatrics that found lack of access to diapers was associated with more frequent pediatric visits for treatment of diaper rash and urinary tract infections.Source: The Journal of Pediatrics
Yale Study: Trends in the Use of Buprenorphine in US Emergency Departments, 2002-2017
Greg Rhee, PhD, Assistant Professor Adjunct, is first author of a paper published in JAMA Network Open that examines the trends of buprenorphine use in emergency departments in the United States from 2002 (when it was approved) through 2017.Source: JAMA Network Open
WHRY Funds Study on Psychological Resilience in COVID-19 Health Care Providers
Women’s Health Research at Yale announced funding for a new collaborative study with researchers at Mt. Sinai Medical Hospital in New York on the personal and professional stressors and coping strategies of frontline health care providers confronting the COVID-19 pandemic