2017
Assessment of a modified technique for air delivery during fluoroscopic-monitored pneumatic intussusception reduction
Jindal G, Graeber BL, Staib LH, Silva CT. Assessment of a modified technique for air delivery during fluoroscopic-monitored pneumatic intussusception reduction. Pediatric Radiology 2017, 47: 1594-1598. PMID: 28681232, DOI: 10.1007/s00247-017-3920-z.Peer-Reviewed Original Research
2016
Brain responses to biological motion predict treatment outcome in young children with autism
Yang D, Pelphrey KA, Sukhodolsky DG, Crowley MJ, Dayan E, Dvornek NC, Venkataraman A, Duncan J, Staib L, Ventola P. Brain responses to biological motion predict treatment outcome in young children with autism. Translational Psychiatry 2016, 6: e948-e948. PMID: 27845779, PMCID: PMC5314125, DOI: 10.1038/tp.2016.213.Peer-Reviewed Original ResearchConceptsAutism spectrum disorderYoung childrenSocial information processingMultivariate pattern analysisMotivation/rewardBiological motionCore deficitComplex neurodevelopmental disorderBrain responsesResponse treatmentSpectrum disorderNeurobiological markersNeural predictorsInformation processingBehavioral interventionsIndividual childrenNeurodevelopmental disordersCurrent findingsNeural circuitsBehavioral deficitsEarly childhoodChildrenUnsuccessful interventionsNeurobiomarkersPattern analysisPivotal response treatment prompts a functional rewiring of the brain among individuals with autism spectrum disorder
Venkataraman A, Yang D, Dvornek N, Staib LH, Duncan JS, Pelphrey KA, Ventola P. Pivotal response treatment prompts a functional rewiring of the brain among individuals with autism spectrum disorder. Neuroreport 2016, 27: 1081-1085. PMID: 27532879, PMCID: PMC5007196, DOI: 10.1097/wnr.0000000000000662.Peer-Reviewed Original ResearchConceptsPivotal Response TreatmentAutism spectrum disorderOccipital-temporal cortexAttentional systemResponse treatmentSpectrum disorderOrbitofrontal cortexPosterior cingulateHigh-level objectsBehavioral interventionsLearning mechanismPerception shiftProcessing areasNeural circuitsFunctional rewiringCortexTreatment regimenAutismInterventionNovel Bayesian frameworkCingulateFunctional changesIndividualsDisordersObjects
2015
The clinical impact of gynecologic MRI.
Ratner ES, Staib LH, Cross SN, Raji R, Schwartz PE, McCarthy SM. The clinical impact of gynecologic MRI. American Journal Of Roentgenology 2015, 204: 674-80. PMID: 25714302, DOI: 10.2214/ajr.14.12567.Peer-Reviewed Original ResearchConceptsPelvic MRIFirst modalityClinical managementClinical impactGynecologic massesIndeterminate pelvic massesGroup of patientsResults of MRIRadiologic recordsRadiologic findingsPelvic massClinical recordsUnnecessary surgeryMedical recordsCT examinationsFurther endpointsExact diagnosisPatientsSurgeryIndeterminate massesPatient treatmentMRIDiagnosisModalitiesResultant anxietyUtility of Magnetic Resonance Imaging in the Evaluation of Intraoperatively Confirmed Pelvic Adhesions
Macer ML, Mathur M, Spektor M, Gysler S, Staib L, Kodaman P, McCarthy S. Utility of Magnetic Resonance Imaging in the Evaluation of Intraoperatively Confirmed Pelvic Adhesions. Journal Of Computer Assisted Tomography 2015, 39: 896-900. PMID: 26466105, DOI: 10.1097/rct.0000000000000302.Peer-Reviewed Original ResearchConceptsMagnetic resonance imagingPelvic adhesionsPositive predictive valuePredictive valueResonance imagingSpecificity of MRIGynecologic abdominal surgeryInstitutional review board-approved retrospective analysisNegative predictive valueAnterior culPosterior culAbdominal surgeryOperative reportsInclusion criteriaRetrospective analysisStudy populationBlinded specialistsMRI sensitivityPatientsImaging
2014
Using SUV as a Guide to 18F-FDG Dose Reduction
Cheng DW, Ersahin D, Staib LH, Della Latta D, Giorgetti A, d’Errico F. Using SUV as a Guide to 18F-FDG Dose Reduction. Journal Of Nuclear Medicine 2014, 55: 1998-2002. PMID: 25453048, DOI: 10.2967/jnumed.114.140129.Peer-Reviewed Original Research
2012
Anatomical Brain Images Alone Can Accurately Diagnose Chronic Neuropsychiatric Illnesses
Bansal R, Staib LH, Laine AF, Hao X, Xu D, Liu J, Weissman M, Peterson BS. Anatomical Brain Images Alone Can Accurately Diagnose Chronic Neuropsychiatric Illnesses. PLOS ONE 2012, 7: e50698. PMID: 23236384, PMCID: PMC3517530, DOI: 10.1371/journal.pone.0050698.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAlgorithmsAttention Deficit Disorder with HyperactivityBipolar DisorderBrainChildDepressive Disorder, MajorFemaleHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleMiddle AgedReproducibility of ResultsSchizophreniaSensitivity and SpecificityTourette SyndromeConceptsBrains of personsNeuropsychiatric illnessBrain regionsNeuropsychiatric disordersMRI scansMajor depressive disorderChronic neuropsychiatric disorderAttention-deficit/hyperactivity disorderSpecific neuropsychiatric disordersDifferent neuropsychiatric disordersLarge MRI datasetsAnatomical MRI scansDisease courseCerebral cortexLow familial riskDepressive disorderBiological subtypesTourette syndromeBipolar disorderAnatomical brain imagesClinical diagnosisFamilial riskIllnessDiagnostic accuracyDiagnostic algorithmEarly assessment of the efficacy of digital infrared thermal imaging in pediatric extremity trauma
Silva CT, Naveed N, Bokhari S, Baker KE, Staib LH, Ibrahim SM, Muchantef K, Goodman TR. Early assessment of the efficacy of digital infrared thermal imaging in pediatric extremity trauma. Emergency Radiology 2012, 19: 203-209. PMID: 22362422, DOI: 10.1007/s10140-012-1027-2.Peer-Reviewed Original ResearchConceptsPediatric extremity traumaExtremity traumaSite of painPediatric emergency departmentSite of injuryPain sitesEmergency departmentLimb traumaContralateral limbExtremity radiographsFracture sitePatientsFurther evaluationRadiographsTraumaSame dayEarly assessmentWhole limbIntellectual disabilityLocal hyperthermiaYoung childrenDITIEfficacyLimbFractures
2011
Lateral ventricle volume and psychotic features in adolescents and adults with bipolar disorder
Edmiston EE, Wang F, Kalmar JH, Womer FY, Chepenik LG, Pittman B, Gueorguieva R, Hur E, Spencer L, Staib LH, Constable RT, Fulbright RK, Papademetris X, Blumberg HP. Lateral ventricle volume and psychotic features in adolescents and adults with bipolar disorder. Psychiatry Research 2011, 194: 400-402. PMID: 22041535, PMCID: PMC3225709, DOI: 10.1016/j.pscychresns.2011.07.005.Peer-Reviewed Original ResearchDiffusion Tensor Imaging in Autism Spectrum Disorders: Preliminary Evidence of Abnormal Neural Connectivity
Jou RJ, Jackowski AP, Papademetris X, Rajeevan N, Staib LH, Volkmar FR. Diffusion Tensor Imaging in Autism Spectrum Disorders: Preliminary Evidence of Abnormal Neural Connectivity. Australian & New Zealand Journal Of Psychiatry 2011, 45: 153-162. PMID: 21128874, PMCID: PMC3123660, DOI: 10.3109/00048674.2010.534069.Peer-Reviewed Original Research
2008
Corpus callosum in maltreated children with posttraumatic stress disorder: A diffusion tensor imaging study
Jackowski AP, Douglas-Palumberi H, Jackowski M, Win L, Schultz RT, Staib LW, Krystal JH, Kaufman J. Corpus callosum in maltreated children with posttraumatic stress disorder: A diffusion tensor imaging study. Psychiatry Research 2008, 162: 256-261. PMID: 18296031, PMCID: PMC3771642, DOI: 10.1016/j.pscychresns.2007.08.006.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderCorpus callosumStress disorderPathophysiology of PTSDDiffusion tensor imaging studyHistory of traumaWhite matter developmentEffects of stressWhite matter tractsWhite matter integrityDiffusion tensor imagingStudies of adultsInterhemispheric projectionsPediatric studiesPrimary white matter tractPreclinical studiesNormal controlsPosterior corpusHippocampus atrophyImaging studiesBrain structuresTensor imagingFractional anisotropyCallosumChildren
2003
MRI and PET Study of Deficits in Hippocampal Structure and Function in Women With Childhood Sexual Abuse and Posttraumatic Stress Disorder
Bremner JD, Vythilingam M, Vermetten E, Southwick SM, McGlashan T, Nazeer A, Khan S, Vaccarino LV, Soufer R, Garg PK, Ng CK, Staib LH, Duncan JS, Charney DS. MRI and PET Study of Deficits in Hippocampal Structure and Function in Women With Childhood Sexual Abuse and Posttraumatic Stress Disorder. American Journal Of Psychiatry 2003, 160: 924-932. PMID: 12727697, DOI: 10.1176/appi.ajp.160.5.924.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderChildhood sexual abuseHippocampal volumeEarly childhood sexual abuseHippocampal structureHippocampal functionAbuse-related posttraumatic stress disorderStress disorderSmaller hippocampal volumesPositron emission tomographySexual abuseVerbal declarative memory tasksAnimal studiesBrain areasDeclarative memory taskEmission tomographyPET studiesHippocampal activationWomenEarly stressHippocampusAbused womenDisordersAbuseMagnetic resonanceNeural correlates of declarative memory for emotionally valenced words in women with posttraumatic stress disorder related to early childhood sexual abuse
Bremner JD, Vythilingam M, Vermetten E, Southwick SM, McGlashan T, Staib LH, Soufer R, Charney DS. Neural correlates of declarative memory for emotionally valenced words in women with posttraumatic stress disorder related to early childhood sexual abuse. Biological Psychiatry 2003, 53: 879-889. PMID: 12742675, DOI: 10.1016/s0006-3223(02)01891-7.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderAbuse-related posttraumatic stress disorderMedial prefrontal cortexBrain areasPrefrontal cortexEarly childhood sexual abuseBlood flowChildhood abuse-related posttraumatic stress disorderSexual abuse-related posttraumatic stress disorderStress disorderChildhood sexual abuseCerebral blood flowPositron emission tomographic measurementsSpecific brain areasInferior temporal gyrusInferior parietal cortexMiddle frontal gyrusNeural correlatesTrauma-specific stimuliDeclarative memoryMotor cortexControl subjectsFrontal cortexSymptom provocationAnimal studiesBasal Ganglia Volumes in Patients With Gilles de la Tourette Syndrome
Peterson BS, Thomas P, Kane MJ, Scahill L, Zhang H, Bronen R, King RA, Leckman JF, Staib L. Basal Ganglia Volumes in Patients With Gilles de la Tourette Syndrome. JAMA Psychiatry 2003, 60: 415-424. PMID: 12695320, DOI: 10.1001/archpsyc.60.4.415.Peer-Reviewed Original ResearchConceptsBasal ganglia volumesBasal gangliaCaudate nucleus volumeTourette syndromeGanglia volumesObsessive-compulsive disorderLenticular nucleus volumesTic symptomsNucleus volumeGilles dePathophysiology of TSPrior neuroleptic exposureHealthy control subjectsSeverity of ticsComorbid obsessive-compulsive disorderGreat clinical relevanceAttention-deficit/hyperactivity disorder (ADHD) symptomsHyperactivity disorder symptomsRepeated-measures analysisNeuroleptic exposureControl subjectsFunctional disturbancesTrait abnormalityClinical relevanceGanglia
2002
Childhood Trauma Associated With Smaller Hippocampal Volume in Women With Major Depression
Vythilingam M, Heim C, Newport J, Miller AH, Anderson E, Bronen R, Brummer M, Staib L, Vermetten E, Charney DS, Nemeroff CB, Bremner JD. Childhood Trauma Associated With Smaller Hippocampal Volume in Women With Major Depression. American Journal Of Psychiatry 2002, 159: 2072-2080. PMID: 12450959, PMCID: PMC3230324, DOI: 10.1176/appi.ajp.159.12.2072.Peer-Reviewed Original ResearchConceptsSmaller hippocampal volumesMajor depressive disorderHippocampal volumeDepressive disorderDepressed subjectsDepressed womenHealthy subjectsChildhood abuseUnipolar major depressive disorderRight hippocampal volumeCoronal MRI scansAdrenal axisDepressed patientsMajor depressionControl brain regionsTemporal lobeWhole hippocampusComparison subjectsMRI scansTrauma AssociatedEarly childhood traumaFemale volunteersWhole brainBrain regionsStudy participants
2001
Regional Brain and Ventricular Volumes in Tourette Syndrome
Peterson BS, Staib L, Scahill L, Zhang H, Anderson C, Leckman JF, Cohen DJ, Gore JC, Albert J, Webster R. Regional Brain and Ventricular Volumes in Tourette Syndrome. JAMA Psychiatry 2001, 58: 427-440. PMID: 11343521, DOI: 10.1001/archpsyc.58.5.427.Peer-Reviewed Original ResearchConceptsParieto-occipital regionsTourette syndromeTic symptomsCerebral volumeVentricular volumePathophysiology of TST subjectsWhite matter portionsThalamo-cortical circuitrySignificant inverse associationRegional cerebral volumesHigh-resolution anatomical magnetic resonance imagesStandard anatomical landmarksSex differencesAge-related findingsDorsal prefrontal regionsRegional brainCortico-striatoHealthy childrenHealthy controlsInverse associationHealthy subjectsOccipital volumeTS groupCortical regionsAutomated measurement of latent morphological features in the human corpus callosum
Peterson B, Feineigle P, Staib L, Gore J. Automated measurement of latent morphological features in the human corpus callosum. Human Brain Mapping 2001, 12: 232-245. PMID: 11241874, PMCID: PMC6871880, DOI: 10.1002/1097-0193(200104)12:4<232::aid-hbm1018>3.0.co;2-j.Peer-Reviewed Original ResearchConceptsCorpus callosumSubject characteristicsYears of ageHuman corpus callosumPatient groupCallosum sizeHealthy subjectsMRI scansVentricular volumeCallosumMidsagittal planeFactor scoresNeural correlatesConstruct validityFactor-based analysisConventional measuresFuture studiesMorphological featuresAgePredictive validitySubjectsScoresNormal developmentVarimax rotationFactors
2000
Regional Brain Volume Abnormalities and Long-term Cognitive Outcome in Preterm Infants
Peterson B, Vohr B, Staib L, Cannistraci C, Dolberg A, Schneider K, Katz K, Westerveld M, Sparrow S, Anderson A, Duncan C, Makuch R, Gore J, Ment L. Regional Brain Volume Abnormalities and Long-term Cognitive Outcome in Preterm Infants. JAMA 2000, 284: 1939-1947. PMID: 11035890, DOI: 10.1001/jama.284.15.1939.Peer-Reviewed Original ResearchConceptsRegional brain volumesLong-term cognitive outcomesPreterm childrenPreterm infantsBrain volumeBasal gangliaCorpus callosumCognitive outcomesRegional brain volume abnormalitiesTerm control childrenCase-control studyBrain volume abnormalitiesPoor cognitive outcomesRegional cortical volumesStructural magnetic resonanceMidtemporal cortexPreterm birthPremature birthTemporal hornPerinatal variablesSubgenual cortexUniversity Medical SchoolCortical volumeHigh prevalenceLongitudinal followPreliminary Findings of Antistreptococcal Antibody Titers and Basal Ganglia Volumes in Tic, Obsessive-compulsive, and Attention-Deficit/Hyperactivity Disorders
Peterson BS, Leckman JF, Tucker D, Scahill L, Staib L, Zhang H, King R, Cohen DJ, Gore JC, Lombroso P. Preliminary Findings of Antistreptococcal Antibody Titers and Basal Ganglia Volumes in Tic, Obsessive-compulsive, and Attention-Deficit/Hyperactivity Disorders. JAMA Psychiatry 2000, 57: 364-372. PMID: 10768698, DOI: 10.1001/archpsyc.57.4.364.Peer-Reviewed Original ResearchConceptsBasal ganglia volumesAttention-deficit/hyperactivity disorderAntistreptococcal antibody titersObsessive-compulsive disorderAntibody titersGanglia volumesStreptococcal infectionAntistreptococcal antibodiesPreliminary serological evidencePrior streptococcal infectionRecurrent streptococcal infectionsHyperactivity disorderPresence of ADHDBasal ganglia nucleiHigh antibody titersGlobus pallidus nucleusDSM-IV diagnosisStreptococcal exposurePallidus nucleusAntistreptolysin OOCD comorbiditySerological evidenceSusceptible personsTic disordersDiagnostic comorbidity
1999
Neural Correlates of Memories of Childhood Sexual Abuse in Women With and Without Posttraumatic Stress Disorder
Bremner J, Narayan M, Staib L, Southwick S, McGlashan T, Charney D. Neural Correlates of Memories of Childhood Sexual Abuse in Women With and Without Posttraumatic Stress Disorder. American Journal Of Psychiatry 1999, 156: 1787-1795. PMID: 10553744, PMCID: PMC3233772, DOI: 10.1176/ajp.156.11.1787.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderBlood flowVisual association cortexMedial prefrontal cortexChildhood sexual abusePrefrontal cortexMotor cortexAssociation cortexPosterior cingulateStress disorderBrain blood flowChildhood abuseInferior temporal gyrusPositron emission tomographyNeural correlatesSexual abuseSubcallosal gyrusRight hippocampusLong-term effectsFailure of activationAnterior prefrontal cortexBrain areasAnterior cingulateTraumatic remindersEmission tomography