2020
Serum Levels of Metabolites Produced by Intestinal Microbes and Lipid Moieties Independently Associated With Acute-on-Chronic Liver Failure and Death in Patients With Cirrhosis
Bajaj JS, Reddy KR, O'Leary JG, Vargas HE, Lai JC, Kamath PS, Tandon P, Wong F, Subramanian RM, Thuluvath P, Fagan A, White MB, Gavis EA, Sehrawat T, de la Rosa Rodriguez R, Thacker LR, Sikaroodi M, Garcia-Tsao G, Gillevet PM. Serum Levels of Metabolites Produced by Intestinal Microbes and Lipid Moieties Independently Associated With Acute-on-Chronic Liver Failure and Death in Patients With Cirrhosis. Gastroenterology 2020, 159: 1715-1730.e12. PMID: 32687928, PMCID: PMC7680282, DOI: 10.1053/j.gastro.2020.07.019.Peer-Reviewed Original ResearchMeSH KeywordsAcute-On-Chronic Liver FailureAdultAgedBacteriaBiomarkersDatabases, FactualFecesFemaleGastrointestinal MicrobiomeHospital MortalityHumansLipidomicsLipidsLiver CirrhosisMaleMetabolomicsMiddle AgedNorth AmericaPatient AdmissionPredictive Value of TestsPrognosisProspective StudiesRisk AssessmentRisk FactorsTime FactorsConceptsDevelopment of ACLFSerum levelsClinical parametersStool samplesSerum metabolitesEnd-stage liver diseaseWhite blood cell countSerum samplesFecal microbiomeTertiary hepatology centersChronic liver failureDay of admissionMultiple centersTime of admissionBlood cell countNorth American ConsortiumLevels of phospholipidsMetabolomic analysisHepatology centersHospital admissionLiver failureClinical featuresLiver diseaseACLFEstrogen metabolites
2011
Congenital Hepatic Vascular Malformations
Garcia-Tsao G. Congenital Hepatic Vascular Malformations. 2011, 213-227. DOI: 10.1007/978-1-4419-8327-5_14.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2010
Antibiotic Prophylaxis and Management of Bacterial Infections
Lim J, Tandon P, Garcia-Tsao G. Antibiotic Prophylaxis and Management of Bacterial Infections. Clinical Gastroenterology 2010, 395-410. DOI: 10.1007/978-1-60761-866-9_20.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsSpontaneous bacterial peritonitisBacterial infectionsAntibiotic prophylaxisAcute kidney injuryRecurrent variceal hemorrhageHigh-risk patientsRole of antibioticsAcute decompensationKidney injuryVariceal hemorrhageBacterial peritonitisImportant complicationLiver failureClinical featuresCommon infectionsRisk factorsRole of albuminCirrhosisCommon precipitantsProphylaxisInfectionCommon typePatientsDecompensationPeritonitis
2008
Bacterial Infections, Sepsis, and Multiorgan Failure in Cirrhosis
Tandon P, Garcia-Tsao G. Bacterial Infections, Sepsis, and Multiorgan Failure in Cirrhosis. Seminars In Liver Disease 2008, 28: 026-042. PMID: 18293275, DOI: 10.1055/s-2008-1040319.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsSpontaneous bacterial peritonitisBacterial infectionsMultiorgan failureBacterial translocationSystemic inflammatory response syndromeHigh-risk patientsInflammatory response syndromeHyperdynamic circulatory stateRole of antibioticsAdrenal insufficiencyBacterial peritonitisImportant complicationResponse syndromeBacterial overgrowthCirculatory stateClinical featuresCommon infectionsRisk factorsRole of albuminCirrhosisPrognostic modelInfectionSepsisComplicationsPatients
1994
A Comparative Clinical Study of Idiopathic Portal Hypertension, Extrahepatic Portal Vein Thrombosis, and Cirrhosis
Orozco H, Takahashi T, Garcia-Tsao G, Mercado M, Prado E, Nava R. A Comparative Clinical Study of Idiopathic Portal Hypertension, Extrahepatic Portal Vein Thrombosis, and Cirrhosis. Journal Of Clinical Gastroenterology 1994, 19: 217-221. PMID: 7806833, DOI: 10.1097/00004836-199410000-00010.Peer-Reviewed Original ResearchConceptsExtrahepatic portal vein thrombosisIdiopathic portal hypertensionPortal vein thrombosisLiver cirrhosisPortal hypertensionVein thrombosisClinical featuresLC patientsComparative clinical studySeparate clinical entityLiver failureLaboratory variablesClinical entityRetrospective studyClinical studiesPatientsStatistical differenceHypertensionCirrhosisThrombosisHigher proportionSurvivalSimilar distributionGroup