2022
SAT496 SBP vs. non-SBP bacterial infections at admission have comparable outcomes in a multi-center cohort of inpatients with cirrhosis
O’Leary J, Reddy K, Tandon P, Kamath P, Garcia-Tsao G, Wong F, Lai J, Subramanian R, Thuluvath P, Maliakkal B, Vargas H, Biggins S, Thacker L, Bajaj J. SAT496 SBP vs. non-SBP bacterial infections at admission have comparable outcomes in a multi-center cohort of inpatients with cirrhosis. Journal Of Hepatology 2022, 77: s887-s888. DOI: 10.1016/s0168-8278(22)02066-9.Peer-Reviewed Original ResearchSa1456: SBP VERSUS NON-SBP BACTERIAL INFECTIONS AT ADMISSION HAVE COMPARABLE OUTCOMES IN A MULTI-CENTER COHORT OF INPATIENTS WITH CIRRHOSIS
O'Leary J, Reddy K, Tandon P, Kamath P, Garcia-Tsao G, Wong F, Lai J, Subramanian R, Thuluvath P, Maliakkal B, Vargas H, Biggins S, Thacker L, Bajaj J. Sa1456: SBP VERSUS NON-SBP BACTERIAL INFECTIONS AT ADMISSION HAVE COMPARABLE OUTCOMES IN A MULTI-CENTER COHORT OF INPATIENTS WITH CIRRHOSIS. Gastroenterology 2022, 162: s-1175-s-1176. DOI: 10.1016/s0016-5085(22)63501-7.Peer-Reviewed Original ResearchAscites and its complications
Garcia‐Tsao G. Ascites and its complications. 2022, 522-531. DOI: 10.1002/9781119600527.ch59.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsCirrhotic ascitesPresence of ascitesMainstay of therapySevere liver diseaseSpontaneous bacterial peritonitisAccumulation of fluidHepatorenal syndromePeritoneal malignancyUncomplicated ascitesAbdominal ultrasonographySodium restrictionCirrhotic patientsHepatic hydrothoraxBacterial peritonitisHeart failureLiver diseaseDecompensated stageCommon causePeritoneal cavityAscitesPatientsMost cost-effective methodBacterial infectionsCirrhosisCommon type
2018
Ascites
Garcia‐Tsao G. Ascites. 2018, 127-150. DOI: 10.1002/9781119237662.ch9.Peer-Reviewed Educational MaterialsLarge-volume paracentesesHepatorenal syndromeRefractory ascitesCirrhotic ascitesCommon decompensating eventMassive hepatic metastasesPlasma renin activitySecond-line treatmentFormation of ascitesDevelopment of ascitesCost-effective treatmentSinusoidal hypertensionCardiac indexRenin activityVasodilatory stateHepatic metastasesMalignant ascitesAscites formationCommon precipitantsAscitesHigh mortalityBacterial infectionsHyponatremiaMain predictorsPatients
2012
High Prevalence of Antibiotic-Resistant Bacterial Infections Among Patients With Cirrhosis at a US Liver Center
Tandon P, DeLisle A, Topal JE, Garcia–Tsao G. High Prevalence of Antibiotic-Resistant Bacterial Infections Among Patients With Cirrhosis at a US Liver Center. Clinical Gastroenterology And Hepatology 2012, 10: 1291-1298. PMID: 22902776, PMCID: PMC3891826, DOI: 10.1016/j.cgh.2012.08.017.Peer-Reviewed Original ResearchConceptsSystemic antibioticsBacterial infectionsAntibiotic-resistant bacterial infectionsOdds ratioTertiary care transplant centerCulture-positive infectionsSpontaneous bacterial peritonitisUrinary tract infectionMultivariate logistic regressionPercent of infectionsFirst bacterial infectionInfectious episodesLiver centersLiver unitTract infectionsBacterial peritonitisTransplant centersRisk factorsHigh prevalenceNosocomial infectionsPatientsUS hospitalsCirrhosisAbstractTextInfection
2011
Ascites
Garcia‐Tsao G. Ascites. 2011, 210-233. DOI: 10.1002/9781444341294.ch10.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsHepatorenal syndromeBacterial infectionsBaseline renal dysfunctionPeripheral arterial vasodilatationAcute kidney injurySecond-line treatmentMainstay of treatmentSpontaneous bacterial peritonitisSympathetic nervous systemEffective blood volumeSpontaneous bacterial infectionsCommon bacterial infectionsSigns of infectionLong-term safetyDiagnostic paracentesisIntravenous albuminPrerenal typeSinusoidal hypertensionAldosterone systemArterial vasodilatationKidney injuryLiver transplantationRefractory ascitesRenal dysfunctionSodium restrictionSpontaneous Bacterial Peritonitis – Prophylaxis and Treatment
Wiest R, Garcia-Tsao G. Spontaneous Bacterial Peritonitis – Prophylaxis and Treatment. Frontiers Of Gastrointestinal Research 2011, 28: 65-82. DOI: 10.1159/000318963.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsSpontaneous bacterial peritonitisAntibiotic prophylaxisHistory of SBPSpontaneous bacterial peritonitis prophylaxisLong-term antibiotic treatmentPrompt effective therapyPrognosis of patientsIdentification of patientsSevere bacterial infectionsLife-threatening infectionsSpontaneous bacteremiaGastrointestinal hemorrhageCirrhotic patientsBacterial peritonitisTreatment failureAntibiotic treatmentClinical trialsCurrent guidelinesEffective therapyFirst episodeHigh riskProphylaxisPatientsBacterial infectionsSpontaneous infection
2010
Antibiotic Prophylaxis and Management of Bacterial Infections
Lim J, Tandon P, Garcia-Tsao G. Antibiotic Prophylaxis and Management of Bacterial Infections. Clinical Gastroenterology 2010, 395-410. DOI: 10.1007/978-1-60761-866-9_20.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsSpontaneous bacterial peritonitisBacterial infectionsAntibiotic prophylaxisAcute kidney injuryRecurrent variceal hemorrhageHigh-risk patientsRole of antibioticsAcute decompensationKidney injuryVariceal hemorrhageBacterial peritonitisImportant complicationLiver failureClinical featuresCommon infectionsRisk factorsRole of albuminCirrhosisCommon precipitantsProphylaxisInfectionCommon typePatientsDecompensationPeritonitis
2008
Bacterial Infections, Sepsis, and Multiorgan Failure in Cirrhosis
Tandon P, Garcia-Tsao G. Bacterial Infections, Sepsis, and Multiorgan Failure in Cirrhosis. Seminars In Liver Disease 2008, 28: 026-042. PMID: 18293275, DOI: 10.1055/s-2008-1040319.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsSpontaneous bacterial peritonitisBacterial infectionsMultiorgan failureBacterial translocationSystemic inflammatory response syndromeHigh-risk patientsInflammatory response syndromeHyperdynamic circulatory stateRole of antibioticsAdrenal insufficiencyBacterial peritonitisImportant complicationResponse syndromeBacterial overgrowthCirculatory stateClinical featuresCommon infectionsRisk factorsRole of albuminCirrhosisPrognostic modelInfectionSepsisComplicationsPatients
2005
Sepsis in cirrhosis: report on the 7th meeting of the International Ascites Club
Wong F, Bernardi M, Balk R, Christman B, Moreau R, Garcia-Tsao G, Patch D, Soriano G, Hoefs J, Navasa M. Sepsis in cirrhosis: report on the 7th meeting of the International Ascites Club. Gut 2005, 54: 718. PMID: 15831923, PMCID: PMC1774473, DOI: 10.1136/gut.2004.038679.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsGastrointestinal bleedSepsis syndromeBacterial infectionsInternational Ascites ClubElevated D-dimerSystemic inflammatory responseSpontaneous bacterial peritonitisFurther tissue injuryPresence of infectionNitric oxide synthaseTumor necrosis factorUse of antibioticsUse of albuminSubclinical coagulopathyProphylactic antibioticsRenal impairmentCirrhotic patientsLiver dysfunctionRenal failureBacterial peritonitisBacterial translocationD-dimerReticuloendothelial functionProduction of superoxideInflammatory response