Breast Imaging

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General Information

Smilow Cancer Hospital - 35 Park Street
New Haven, CT 06520-8042
Admin Assistant, Lori Raccio

The Yale Breast Imaging section is devoted to providing state-of-the-art quality breast imaging and diagnosis. This includes screening and diagnostic mammography, ultrasound, MRI and interventional procedures including pre-operative needle localization, stereotactic US, and MR core biopsy. As a comprehensive breast center, the staff and radiologists are all highly specialized to provide the best care possible.

The radiologists are nationally recognized leaders in breast imaging. Active research includes biopsy outcomes and management, breast MRI, and digital tomosynthesis imaging.

Section's statistics (per year)

18,000 Total studies
9000 Screenings
5500 Diagnostic exams
2000 Breast Ultrasounds
800 biopsies
350 MRI

The Breast Imaging section is an integral part of the Yale-New Haven Breast Center of Yale-New Haven Hospital. In addition to teaching Yale Medical students and Diagnostic Radiology residents, the section hosts fellowships through either Breast Imaging or a combined program with Body Imaging.

Research Direction

  • Breast MRI
  • Breast interventional procedures
  • Digital tomosynthesis imaging
  • Improvements in breast biopsy
  • Breast cancer screening
  • Breast ultrasound and elastography


Books & Chapters:

  • Regina Hooley, Leslie Scoutt & Liane Philpotts."Breast Ultrasound: State of the Art" is scheduled to be published in the September issue in Radiology.
  • Dr. Regina Hooley has written the following chapters in Diagnostic Imaging: Breast, 2nd Edition. 
    -Breast Tomosynthesis
    -Breast MRI: Overview
    -Diagnostic Mammography
    -Breast Elastography
    -Ultrasound-guided Core Needle Biopsy

Recent Publications

Durand MA, Philpotts L: Digital Breast Tomosynthesis for Women Older Than 70 Years. JAMA Intern Med. 2019 Jun 1. PMID: 31157846

Philpotts LE, Durand MA: Good News for Older Women Undergoing Screening Mammography with Digital Breast Tomosynthesis. Radiology. 2019 Jun; 2019 Apr 2. PMID: 30942669

Philpotts LE: Density Variation among Mammographic Modalities Will Likely Impact Imaging Management and Risk Stratification. Radiology. 2019 May; 2019 Mar 19. PMID: 30913019

Braman N, Prasanna P, Whitney J, Singh S, Beig N, Etesami M, Bates DDB, Gallagher K, Bloch BN, Vulchi M, Turk P, Bera K, Abraham J, Sikov WM, Somlo G, Harris LN, Gilmore H, Plecha D, Varadan V, Madabhushi A: Association of Peritumoral Radiomics With Tumor Biology and Pathologic Response to Preoperative Targeted Therapy for HER2 (ERBB2)-Positive Breast Cancer. JAMA Netw Open. 2019 Apr 5; 2019 Apr 5. PMID: 31002322

Hooley R: Are More Experienced Readers Better at Interpreting Digital Breast Tomosynthesis Results? Radiology. 2019 Apr; 2019 Feb 26. PMID: 30806602

Butler R, Lavin PT, Tucker FL, Barke LD, Böhm-Vélez M, Destounis S, Grobmyer SR, Katzen J, Kist KA, Makariou EV, Schilling KJ, Young CA, Dogan BE, Neuschler EI: Optoacoustic Breast Imaging: Imaging-Pathology Correlation of Optoacoustic Features in Benign and Malignant Breast Masses. AJR Am J Roentgenol. 2018 Nov; 2018 Aug 14. PMID: 30106610

Guo Y, Raghu M, Durand M, Hooley R: Retroareolar masses and intraductal abnormalities detected on screening ultrasound: can biopsy be avoided? Br J Radiol. 2018 Oct; 2018 Feb 6. PMID: 29338316

Neuschler EI, Lavin PT, Tucker FL, Barke LD, Bertrand ML, Böhm-Vélez M, Destounis S, Dogan BE, Grobmyer SR, Katzen J, Kist KA, Makariou EV, Parris TM, Young CA, Butler R: Downgrading and Upgrading Gray-Scale Ultrasound BI-RADS Categories of Benign and Malignant Masses With Optoacoustics: A Pilot Study. AJR Am J Roentgenol. 2018 Sep; 2018 Jul 5. PMID: 29975115

Philpotts LE: Machine Detection of High Breast Density: Worse Outcomes for Our Patients. Radiology. 2018 Aug; 2018 Jun 26. PMID: 29944080

Butler RS: Invited Commentary: Handheld or Automated-Staying Focused on the Goals of Screening US, with Response from Drs van Zelst and Mann. Radiographics. 2018 May-Jun. PMID: 29757727

Neuschler EI, Butler R, Young CA, Barke LD, Bertrand ML, Böhm-Vélez M, Destounis S, Donlan P, Grobmyer SR, Katzen J, Kist KA, Lavin PT, Makariou EV, Parris TM, Schilling KJ, Tucker FL, Dogan BE: A Pivotal Study of Optoacoustic Imaging to Diagnose Benign and Malignant Breast Masses: A New Evaluation Tool for Radiologists. Radiology. 2018 May; 2017 Nov 27. PMID: 29178816

Durand MA: Synthesized Mammography: Clinical Evidence, Appearance, and Implementation. Diagnostics (Basel). 2018 Apr 4; 2018 Apr 4. PMID: 29617294

Geisel J, Raghu M, Hooley R: The Role of Ultrasound in Breast Cancer Screening: The Case for and Against Ultrasound. Semin Ultrasound CT MR. 2018 Feb; 2017 Sep 22. PMID: 29317037

Rassouli N, Etesami M, Dhanantwari A, Rajiah P: Detector-based spectral CT with a novel dual-layer technology: principles and applications. Insights Imaging. 2017 Dec; 2017 Oct 6. PMID: 28986761

Hooley RJ, Philpotts LE: Reply to "Digital Breast Tomosynthesis Assists in Differentiating Vascular Calcification From Malignant Calcification". AJR Am J Roentgenol. 2017 Aug. PMID: 28731809

Rafferty EA, Rose SL, Miller DP, Durand MA, Conant EF, Copit DS, Friedewald SM, Plecha DM, Ott IL, Hayes MK, Carlson KL, Cink TM, Barke LD, Greer LN, Niklason LT: Effect of age on breast cancer screening using tomosynthesis in combination with digital mammography. Breast Cancer Res Treat. 2017 Aug; 2017 May 18. PMID: 28523569

Moothathu NS, Philpotts LE, Busch SH, Gross CP, Staib LH, Hooley RJ: Knowledge of Density and Screening Ultrasound. Breast J. 2017 May; 2016 Dec 10. PMID: 27943500

Durand MA, Hooley RJ: Implementation of Whole-Breast Screening Ultrasonography. Radiol Clin North Am. 2017 May; 2017 Jan 30. PMID: 28411678

Hooley RJ: Breast Density Legislation and Clinical Evidence. Radiol Clin North Am. 2017 May; 2017 Mar 1. PMID: 28411677

Hooley RJ, Durand MA, Philpotts LE: Advances in Digital Breast Tomosynthesis. AJR Am J Roentgenol. 2017 Feb; 2016 Oct 27. PMID: 27786548

Teng E, Broer PN, Heidekrueger PI, Forte AJ, Lentz R, Durand M, Raghu M, Kwei SL: In Vivo Changes of Breast Perfusion After Augmentation. Aesthet Surg J. 2016 Nov; 2016 Sep 13. PMID: 27625032

Kalra VB, Wu X, Haas BM, Forman HP, Philpotts LE: Cost-Effectiveness of Tomosynthesis in Annual Screening Mammography. AJR Am J Roentgenol. 2016 Nov; 2016 Aug 22. PMID: 27547861

Sen LQ, Berg WA, Hooley RJ, Carter GJ, Desouki MM, Sumkin JH: Core Breast Biopsies Showing Lobular Carcinoma In Situ Should Be Excised and Surveillance Is Reasonable for Atypical Lobular Hyperplasia. AJR Am J Roentgenol. 2016 Nov; 2016 Aug 17. PMID: 27532153

Raghu M, Durand MA, Andrejeva L, Goehler A, Michalski MH, Geisel JL, Hooley RJ, Horvath LJ, Butler R, Forman HP, Philpotts LE: Tomosynthesis in the Diagnostic Setting: Changing Rates of BI-RADS Final Assessment over Time. Radiology. 2016 Oct; 2016 May 3. PMID: 27139264

Simmons NR, Xu ML, Tavassoli FA, Geisel J, Killelea B, Philpotts LE: A Rare Presentation of Rosai-Dorfman Disease as a Breast Mass. Breast J. 2016 Sep; 2016 Jun 27. PMID: 27345754

Hayse B, Hooley RJ, Killelea BK, Horowitz NR, Chagpar AB, Lannin DR: Breast cancer biology varies by method of detection and may contribute to overdiagnosis. Surgery. 2016 Aug; 2016 May 27. PMID: 27241117

Simmons NR, Ozerdem U, Philpotts LE, Tavassoli F: An Interesting Presentation of Ischemic Septal Panniculitis of the Breast. Breast J. 2016 Jul; 2016 Apr 18. PMID: 27092964

Rafferty EA, Durand MA, Conant EF, Copit DS, Friedewald SM, Plecha DM, Miller DP: Breast Cancer Screening Using Tomosynthesis and Digital Mammography in Dense and Nondense Breasts. JAMA. 2016 Apr 26. PMID: 27115381

Durand MA, Wang S, Hooley RJ, Raghu M, Philpotts LE: Tomosynthesis-detected Architectural Distortion: Management Algorithm with Radiologic-Pathologic Correlation. Radiographics. 2016 Mar-Apr. PMID: 26963448

Sheiman LS, Levesque PH: The In's and Out's of Ductography: A Comprehensive Review. Curr Probl Diagn Radiol. 2016 Jan-Feb; 2015 Jun 5. PMID: 26163736

Oliveira K, Andrejeva-Wright L, Maerz LL: Imaging Techniques in Emergency Surgeries. Int Anesthesiol Clin. 2016 Winter. PMID: 26655507

Butler RS: Invited commentary: The breast density dilemma--challenges, lessons, and future directions. Radiographics. 2015 Mar-Apr. PMID: 25763720

Durand MA, Haas BM, Yao X, Geisel JL, Raghu M, Hooley RJ, Horvath LJ, Philpotts LE: Early clinical experience with digital breast tomosynthesis for screening mammography. Radiology. 2015 Jan; 2014 Sep 1. PMID: 25188431

Amirbekian S, Hooley RJ: Ultrasound evaluation of pelvic pain. Radiol Clin North Am. 2014 Nov; 2014 Nov 4. PMID: 25444102

Friedewald SM, Rafferty EA, Rose SL, Durand MA, Plecha DM, Greenberg JS, Hayes MK, Copit DS, Carlson KL, Cink TM, Barke LD, Greer LN, Miller DP, Conant EF: Breast cancer screening using tomosynthesis in combination with digital mammography. JAMA. 2014 Jun 25. PMID: 25058084

Raghu M, Hooley R: Breast ultrasound for the interventionalist. Tech Vasc Interv Radiol. 2014 Mar. PMID: 24636327

Haas BM, Kalra V, Geisel J, Raghu M, Durand M, Philpotts LE: Comparison of tomosynthesis plus digital mammography and digital mammography alone for breast cancer screening. Radiology. 2013 Dec; 2013 Oct 28. PMID: 23901124

Killelea BK, Chagpar AB, Bishop J, Horowitz NR, Christy C, Tsangaris T, Raghu M, Lannin DR: Is there a correlation between breast cancer molecular subtype using receptors as surrogates and mammographic appearance? Ann Surg Oncol. 2013 Oct; 2013 Aug 22. PMID: 23975299

Hooley RJ, Scoutt LM, Philpotts LE: Breast ultrasonography: state of the art. Radiology. 2013 Sep. PMID: 23970509

Butler RS, Chen C, Vashi R, Hooley RJ, Philpotts LE: 3.0 Tesla vs 1.5 Tesla breast magnetic resonance imaging in newly diagnosed breast cancer patients. World J Radiol. 2013 Aug 28. PMID: 24003354

Doddamane I, Butler R, Jhaveri A, Chung GG, Cheng D: Where does radioimmunotherapy fit in the management of breast cancer? Immunotherapy. 2013 Aug. PMID: 23902558

Killelea BK, Lannin DR, Horvath LJ, Horowitz NR, Chagpar AB: Factors associated with breast MRI use: a population-based analysis. Ann Surg Oncol. 2013 Jun; 2012 Dec 1. PMID: 23208129

Vashi R, Hooley R, Butler R, Geisel J, Philpotts L: Breast imaging of the pregnant and lactating patient: physiologic changes and common benign entities. AJR Am J Roentgenol. 2013 Feb. PMID: 23345354

Vashi R, Hooley R, Butler R, Geisel J, Philpotts L: Breast imaging of the pregnant and lactating patient: imaging modalities and pregnancy-associated breast cancer. AJR Am J Roentgenol. 2013 Feb. PMID: 23345353

Hooley RJ, Greenberg KL, Stackhouse RM, Geisel JL, Butler RS, Philpotts LE: Screening US in patients with mammographically dense breasts: initial experience with Connecticut Public Act 09-41. Radiology. 2012 Oct; 2012 Jun 21. PMID: 22723501

Meyers AB, Philpotts LE: A case of fat necrosis acquiring worrisome features. Breast J. 2011 Sep-Oct; 2011 Aug 9. PMID: 21827560

Hooley RJ, Andrejeva L, Scoutt LM: Breast cancer screening and problem solving using mammography, ultrasound, and magnetic resonance imaging. Ultrasound Q. 2011 Mar. PMID: 21343800

Philpotts LE: Comprehensive breast imaging 2010. Semin Roentgenol. 2011 Jan. PMID: 21134524

Philpotts LE: MR intervention: indications, technique, correlation and histologic. Magn Reson Imaging Clin N Am. 2010 May. PMID: 20494315

Philpotts LE: Percutaneous breast biopsy: emerging techniques and continuing controversies. Semin Roentgenol. 2007 Oct. PMID: 17919524

Rubinowitz AN, Siegel MD, Tocino I: Thoracic imaging in the ICU. Crit Care Clin. 2007 Jul. PMID: 17900484

Lannin DR, Ponn T, Andrejeva L, Philpotts L: Should all breast cancers be diagnosed by needle biopsy? Am J Surg. 2006 Oct. PMID: 16978947

Kwong MS, Chung GG, Horvath LJ, Ward BA, Hsu AD, Carter D, Tavassoli F, Haffty B, Burtness BA: Postchemotherapy MRI overestimates residual disease compared with histopathology in responders to neoadjuvant therapy for locally advanced breast cancer. Cancer J. 2006 May-Jun. PMID: 16803680

Philpotts LE, Hooley RJ, Lee CH: Comparison of automated versus vacuum-assisted biopsy methods for sonographically guided core biopsy of the breast. AJR Am J Roentgenol. 2003 Feb. PMID: 12540431

Philpotts LE, Smith RA: Screening for breast cancer. Semin Roentgenol. 2003 Jan. PMID: 12698588