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Zuoheng Anita Wang, PhD

Associate Professor of Biostatistics

Contact Information

Zuoheng Anita Wang, PhD

Mailing Address

  • Biostatistics

    60 College St, Yale School of Public Health

    New Haven, CT 06520

    United States

Research Summary

Dr. Wang's research focuses on combining genetics, genomics, immunology, and statistical modeling to answer biologically important questions in genetic epidemiological studies. Dr. Wang's statistical expertise lies in kernel machine methods, mixed effects models, correlated data, and longitudinal data analysis. She develops statistically innovative methods and computationally efficient tools in large-scale genetic and genomic studies to identify genetic susceptibility variants and advance the understanding of the etiology of complex diseases including alcohol and drug abuse, asthma, obesity, cardiovascular diseases, and cancer. Current studies include using next-generation sequencing data to detect rare genetic variants in longitudinal genetic studies, combining knowledge in genomics and immunology to understand the risk of breast cancer survival, and differential gene expression in single-cell RNA sequencing data.

Specialized Terms: Genetics; Bioinformatics; Genomics

Coauthors

Research Interests

Genetics; Biomarkers; Statistics; Genomics

Public Health Interests

Bioinformatics; Biomarkers; Cancer; Genetics, Genomics, Epigenetics

Selected Publications

  • Computational and Statistical Methods for Single-Cell RNA Sequencing DataWang Z, Yan X. Computational and Statistical Methods for Single-Cell RNA Sequencing Data 2022, 3-35. DOI: 10.1007/978-3-662-65902-1_1.
  • Maximum likelihood estimation of nonlinear mixed-effects models with crossed random effects by combining first-order conditional linearization and sequential quadratic programmingFu L, Wang M, Wang Z, Song X, Tang S. Maximum likelihood estimation of nonlinear mixed-effects models with crossed random effects by combining first-order conditional linearization and sequential quadratic programming International Journal Of Biomathematics 2019, 12: 1950040. DOI: 10.1142/s1793524519500402.
  • Isolation and characterization of a poplar d-type cyclin gene associated with the SHORT-ROOT/SCARECROW networkXu M, Liu S, Xuan L, Huang M, Wang Z. Isolation and characterization of a poplar d-type cyclin gene associated with the SHORT-ROOT/SCARECROW network Trees 2015, 30: 255-263. DOI: 10.1007/s00468-015-1296-y.
  • A Genome-Wide Association Study on Obesity and Obesity-Related TraitsWang K, Li W, Zhang C, Wang Z, Glessner J, Grant S, Zhao H, Hakonarson H, Price R. A Genome-Wide Association Study on Obesity and Obesity-Related Traits 2014, 57-69. DOI: 10.1201/b16443-4.
  • Prognostic significance of the AJCC staging in patients with squamous cell carcinoma of the oropharynx.Acevedo-Gadea C, Baumgart M, Wang Z, Deshpande H, Davies M, Decker R, Sasaki C, Judson B, Herbst R, Morgensztern D. Prognostic significance of the AJCC staging in patients with squamous cell carcinoma of the oropharynx. Journal Of Clinical Oncology 2012, 30: 5529-5529. DOI: 10.1200/jco.2012.30.15_suppl.5529.
  • Influence of extracapsular extension on lymph node staging for patients with squamous cell carcinoma of the head and neck.Baumgart M, Acevedo-Gadea C, Wang Z, Buta E, Davies M, Deshpande H, Decker R, Sasaki C, Judson B, Herbst R, Morgensztern D. Influence of extracapsular extension on lymph node staging for patients with squamous cell carcinoma of the head and neck. Journal Of Clinical Oncology 2012, 30: 5532-5532. DOI: 10.1200/jco.2012.30.15_suppl.5532.
  • Correction: A Genome-Wide Association Study on Obesity and Obesity-Related TraitsWang K, Li W, Zhang C, Wang Z, Glessner J, Grant S, Zhao H, Hakonarson H, Price R. Correction: A Genome-Wide Association Study on Obesity and Obesity-Related Traits PLOS ONE 2012, 7: 10.1371/annotation/a34ee94e-3e6a-48bd-a19e-398a4bb88580. PMCID: PMC3293772, DOI: 10.1371/annotation/a34ee94e-3e6a-48bd-a19e-398a4bb88580.
  • Abstract 349: Fascin expression in colorectal cancer metastases predicts survival after curative-intent surgerySullivan C, Guo X, Wang Z, Theoharis C, Rimm D, Boffa D. Abstract 349: Fascin expression in colorectal cancer metastases predicts survival after curative-intent surgery Cancer Research 2011, 71: 349-349. DOI: 10.1158/1538-7445.am2011-349.
  • Joint Functional Mapping of Quantitative Trait Loci for HIV-1 and CD4+ DynamicsWang Z, Li Y, Li Q, Wu R. Joint Functional Mapping of Quantitative Trait Loci for HIV-1 and CD4+ Dynamics The International Journal Of Biostatistics 2009, 5 DOI: 10.2202/1557-4679.1136.