Vincent Quagliarello, MD
Professor of Medicine (Infectious Diseases); Clinical Chief, Infectious Diseases; Vice Chair for Education and Academic Affairs, Department of Internal Medicine
Research & Publications
Biography
News
Research Summary
Dr. Quagliarello is a nationally recognized investigator in the pathophysiology and management of meningitis, and the prognostic classification and management of endocarditis. For the past several years, his scholarship has focused on infections among older adults as an NIH R01 funded principal investigator and a recipient of an NIH K07 Academic Leadership Award to mentor trainees at the postdoctoral and junior faculty level to develop interdisciplinary research at the interface of Infectious Diseases and Geriatrics.
Specialized Terms: Observational research methods for understanding infectious disease
Coauthors
Research Interests
Endocarditis; Meningitis; Nursing Homes; Pneumonia; Infectious Disease Medicine
Selected Publications
- Prevalence and treatment of postobstructive pneumonia among older adults with advanced cancerLee S, O’Donovan L, Cohen A, Gautam S, Quagliarello V, Juthani-Mehta M, Datta R. Prevalence and treatment of postobstructive pneumonia among older adults with advanced cancer Antimicrobial Stewardship & Healthcare Epidemiology 2022, 2 DOI: 10.1017/ash.2022.293.
- Prevalence and treatment of postobstructive pneumonia among older adults with advanced cancerLee S, O’Donovan L, Cohen A, Gautam S, Quagliarello V, Juthani-Mehta M, Datta R. Prevalence and treatment of postobstructive pneumonia among older adults with advanced cancer Antimicrobial Stewardship & Healthcare Epidemiology 2022, 2: e152. PMID: 36483405, PMCID: PMC9726473, DOI: 10.1017/ash.2022.293.
- 1302. Duration of Antibiotic Therapy for Pneumonia Among Patients with Advanced Cancer: An Opportunity for Antibiotic StewardshipBenson J, Datta R, Quagliarello V, Juthani-Mehta M. 1302. Duration of Antibiotic Therapy for Pneumonia Among Patients with Advanced Cancer: An Opportunity for Antibiotic Stewardship Open Forum Infectious Diseases 2021, 8: s739-s739. DOI: 10.1093/ofid/ofab466.1494.
- 1832. Concordance in End-of-Life Antimicrobial Prescribing Practices among Medicine SubspecialistsDatta R, McManus D, Topal J, Sanft T, Quagliarello V, Dembry L, Morrison L, Juthani-Mehta M. 1832. Concordance in End-of-Life Antimicrobial Prescribing Practices among Medicine Subspecialists Open Forum Infectious Diseases 2018, 5: s521-s522. PMCID: PMC6253110, DOI: 10.1093/ofid/ofy210.1488.
- 1932. Healthcare Utilization in Older vs. Younger Adults on Outpatient Parenteral Antimicrobial Therapy According to Discharge LocationDatta R, Brzozowski K, Canterino J, Malinis M, Quagliarello V, Juthani-Mehta M. 1932. Healthcare Utilization in Older vs. Younger Adults on Outpatient Parenteral Antimicrobial Therapy According to Discharge Location Open Forum Infectious Diseases 2018, 5: s556-s557. PMCID: PMC6252589, DOI: 10.1093/ofid/ofy210.1588.
- 2171. Comparing Surveillance Definitions for Noncatheter-Associated Urinary Tract InfectionsDatta R, Advani S, Rink A, Bianco L, Van Ness P, Quagliarello V, Juthani-Mehta M. 2171. Comparing Surveillance Definitions for Noncatheter-Associated Urinary Tract Infections Open Forum Infectious Diseases 2018, 5: s641-s641. PMCID: PMC6253256, DOI: 10.1093/ofid/ofy210.1827.
- 249. Frequency of Antimicrobial Complications Following Initiation of Palliative Chemotherapy in Advanced Cancer PatientsDatta R, Doyle M, Quagliarello V, Sanft T, Juthani-Mehta M. 249. Frequency of Antimicrobial Complications Following Initiation of Palliative Chemotherapy in Advanced Cancer Patients Open Forum Infectious Diseases 2018, 5: s105-s106. PMCID: PMC6255145, DOI: 10.1093/ofid/ofy210.260.
- 248. Antimicrobial Therapy for Suspected Urinary Tract Infection in Advanced Cancer Patients Transitioning to Comfort MeasuresWang T, Datta R, Zhu M, Quagliarello V, Dembry L, Juthani-Mehta M. 248. Antimicrobial Therapy for Suspected Urinary Tract Infection in Advanced Cancer Patients Transitioning to Comfort Measures Open Forum Infectious Diseases 2018, 5: s105-s105. PMCID: PMC6255465, DOI: 10.1093/ofid/ofy210.259.
- 162. Association Between Antibiotic Use and Multidrug-Resistant Organism Detection in Advanced Cancer Patients on Palliative ChemotherapyDatta R, McManus D, Topal J, Quagliarello V, Juthani-Mehta M. 162. Association Between Antibiotic Use and Multidrug-Resistant Organism Detection in Advanced Cancer Patients on Palliative Chemotherapy Open Forum Infectious Diseases 2018, 5: s14-s15. PMCID: PMC6252583, DOI: 10.1093/ofid/ofy209.032.
- 254. Antimicrobial Use in Hospitalized Older Patients with Advanced CancerZhu M, Datta R, Quagliarello V, Juthani-Mehta M. 254. Antimicrobial Use in Hospitalized Older Patients with Advanced Cancer Open Forum Infectious Diseases 2018, 5: s107-s108. PMCID: PMC6255009, DOI: 10.1093/ofid/ofy210.265.
- Effect of Cranberry Capsules on Bacteriuria Plus Pyuria Among Older Women in Nursing Homes: A Randomized Clinical TrialJuthani-Mehta M, Van Ness PH, Bianco L, Rink A, Rubeck S, Ginter S, Argraves S, Charpentier P, Acampora D, Trentalange M, Quagliarello V, Peduzzi P. Effect of Cranberry Capsules on Bacteriuria Plus Pyuria Among Older Women in Nursing Homes: A Randomized Clinical Trial JAMA 2016, 316: 1879-1887. PMID: 27787564, PMCID: PMC5300771, DOI: 10.1001/jama.2016.16141.
- Cranberry Capsules for Reduction of Bacteriuria Plus Pyuria in Nursing Home Women: A Randomized Clinical TrialJuthani-Mehta M, Van Ness P, Bianco L, Rink A, Rubeck S, Ginter S, Argraves S, Charpentier P, Acampora D, Trentalange M, Quagliarello V, Peduzzi P. Cranberry Capsules for Reduction of Bacteriuria Plus Pyuria in Nursing Home Women: A Randomized Clinical Trial Open Forum Infectious Diseases 2016, 3: 1356. DOI: 10.1093/ofid/ofw172.1059.
- Clinical outcomes of HIV‐infected men with CAPBarakat LA, Juthani-Mehta M, Allore H, Trentalange M, Tate J, Rimland D, Pisani M, Akgün KM, Goetz MB, Butt AA, Rodriguez-Barradas M, Duggal M, Crothers K, Justice AC, Quagliarello VJ. Clinical outcomes of HIV‐infected men with CAP HIV Medicine 2015, 16: 421-430. PMID: 25959543, PMCID: PMC5015437, DOI: 10.1111/hiv.12244.
- The Microbiota and Microbiome in Aging: Potential Implications in Health and Age‐Related DiseasesZapata HJ, Quagliarello VJ. The Microbiota and Microbiome in Aging: Potential Implications in Health and Age‐Related Diseases Journal Of The American Geriatrics Society 2015, 63: 776-781. PMID: 25851728, PMCID: PMC4406803, DOI: 10.1111/jgs.13310.
- A Cluster-Randomized Controlled Trial of a Multicomponent Intervention Protocol for Pneumonia Prevention Among Nursing Home EldersJuthani-Mehta M, Van Ness PH, McGloin J, Argraves S, Chen S, Charpentier P, Miller L, Williams K, Wall D, Baker D, Tinetti M, Peduzzi P, Quagliarello VJ. A Cluster-Randomized Controlled Trial of a Multicomponent Intervention Protocol for Pneumonia Prevention Among Nursing Home Elders Clinical Infectious Diseases 2014, 60: 849-857. PMID: 25520333, PMCID: PMC4415071, DOI: 10.1093/cid/ciu935.
- Outcomes among older adult liver transplantation recipients in the model of end stage liver disease (MELD) era.Malinis MF, Chen S, Allore HG, Quagliarello VJ. Outcomes among older adult liver transplantation recipients in the model of end stage liver disease (MELD) era. Annals Of Transplantation 2014, 19: 478-87. PMID: 25256592, PMCID: PMC4201657, DOI: 10.12659/aot.890934.
- Trends in Hospitalization Rates and Outcomes of Endocarditis Among Medicare BeneficiariesBikdeli B, Wang Y, Kim N, Desai MM, Quagliarello V, Krumholz HM. Trends in Hospitalization Rates and Outcomes of Endocarditis Among Medicare Beneficiaries Journal Of The American College Of Cardiology 2013, 62: 2217-2226. PMID: 23994421, PMCID: PMC4335801, DOI: 10.1016/j.jacc.2013.07.071.
- The Ability of Virulence Factor Expression by Pseudomonas aeruginosa to Predict Clinical Disease in Hospitalized PatientsLedizet M, Murray TS, Puttagunta S, Slade MD, Quagliarello VJ, Kazmierczak BI. The Ability of Virulence Factor Expression by Pseudomonas aeruginosa to Predict Clinical Disease in Hospitalized Patients PLOS ONE 2012, 7: e49578. PMID: 23152923, PMCID: PMC3495863, DOI: 10.1371/journal.pone.0049578.
- Efficacy and effectiveness as aspects of cluster randomized trials with nursing home residents: Methodological insights from a pneumonia prevention trialVan Ness PH, Peduzzi PN, Quagliarello VJ. Efficacy and effectiveness as aspects of cluster randomized trials with nursing home residents: Methodological insights from a pneumonia prevention trial Contemporary Clinical Trials 2012, 33: 1124-1131. PMID: 22917599, PMCID: PMC3468687, DOI: 10.1016/j.cct.2012.08.004.
- Dissemination of Neisseria meningitidisQuagliarello V. Dissemination of Neisseria meningitidis New England Journal Of Medicine 2011, 364: 1573-1575. PMID: 21506747, DOI: 10.1056/nejmcibr1101564.
- Infectious Diseases in the Nursing Home Setting: Challenges and Opportunities for Clinical InvestigationHigh K, Juthani-Mehta M, Quagliarello V. Infectious Diseases in the Nursing Home Setting: Challenges and Opportunities for Clinical Investigation Clinical Infectious Diseases 2010, 51: 931-936. PMID: 20822459, PMCID: PMC3083824, DOI: 10.1086/656411.
- Infections in Long‐Term Care FacilitiesJuthani‐Mehta M, Quagliarello V. Infections in Long‐Term Care Facilities 2010, 287-303. DOI: 10.1128/9781555816803.ch15.
- RESPONSE LETTER TO DR. DRINKAJuthani‐Mehta M, Quagliarello V, Perrelli E, Towle V, Van Ness P, Tinetti M. RESPONSE LETTER TO DR. DRINKA Journal Of The American Geriatrics Society 2009, 57: 2388-2389. DOI: 10.1111/j.1532-5415.2009.02605.x.
- Bronchitis and PneumoniaJuthani-Mehta M, Quagliarello V. Bronchitis and Pneumonia 2009, 81-95. PMCID: PMC7121308, DOI: 10.1007/978-1-60327-534-7_7.
- RESPONSE LETTER TO DRS. DRINKA AND CRNICHJuthani‐Mehta M, Tinetti M, Quagliarello V. RESPONSE LETTER TO DRS. DRINKA AND CRNICH Journal Of The American Geriatrics Society 2008, 56: 378-378. DOI: 10.1111/j.1532-5415.2007.01526.x.
- Short- and Long-term Functional Outcome of Hospitalized Older Adults With Community-acquired PneumoniaSharma G, Han L, Quagliarello V. Short- and Long-term Functional Outcome of Hospitalized Older Adults With Community-acquired Pneumonia Infectious Diseases In Clinical Practice 2006, 14: 365-368. DOI: 10.1097/01.idc.0000227715.26754.e7.
- Prognostic Scoring Systems for Infectious Diseases: Their Applicability to the Care of Older AdultsHigh K, Juthani-Mehta M, Quagliarello V. Prognostic Scoring Systems for Infectious Diseases: Their Applicability to the Care of Older Adults Clinical Infectious Diseases 2004, 38: 692-696. PMID: 14986254, DOI: 10.1086/381688.
- ReplyMcMillan D, Lin C, Aronin S, Quagliarello V. Reply Clinical Infectious Diseases 2002, 34: 879-879. DOI: 10.1086/339803.
- Computed Tomography of the Head before Lumbar Puncture in Adults with Suspected MeningitisHasbun R, Abrahams J, Jekel J, Quagliarello V. Computed Tomography of the Head before Lumbar Puncture in Adults with Suspected Meningitis New England Journal Of Medicine 2001, 345: 1727-1733. PMID: 11742046, DOI: 10.1056/nejmoa010399.
- Community-Acquired Bacterial Meningitis in Adults: Categorization of Causes and Timing of DeathMcMillan D, Lin C, Aronin S, Quagliarello V. Community-Acquired Bacterial Meningitis in Adults: Categorization of Causes and Timing of Death Clinical Infectious Diseases 2001, 33: 969-975. PMID: 11528567, DOI: 10.1086/322612.
- Utility of prognostic stratification in adults with community-acquired bacterial meningitisAronin S, Quagliarello V. Utility of prognostic stratification in adults with community-acquired bacterial meningitis Comprehensive Therapy 2001, 27: 72-77. PMID: 11280860, DOI: 10.1007/s12019-001-0011-7.
- Counterpoint: UNAFs—Perspective and PreventionQuagliarello V, Joiner K. Counterpoint: UNAFs—Perspective and Prevention Clinical Infectious Diseases 2001, 32: 755-756. PMID: 11229843, DOI: 10.1086/319232.
- New Perspectives on Pneumococcal MeningitisAronin S, Quagliarello V. New Perspectives on Pneumococcal Meningitis Hospital Practice 2001, 36: 43-51. PMID: 11220360, DOI: 10.3810/hp.2001.02.228.
- Emergence of West Nile virus encephalitis in the New York metropolitan areaQuagliarello V. Emergence of West Nile virus encephalitis in the New York metropolitan area Current Infectious Disease Reports 2000, 2: 325-326. PMID: 11095872, DOI: 10.1007/s11908-000-0010-3.
- Cutaneous leishmaniasis in an Italian womanTunsiripat M, Lee S, Quagliarello V. Cutaneous leishmaniasis in an Italian woman The American Journal Of Medicine 2000, 109: 69-70. PMID: 10991740, DOI: 10.1016/s0002-9343(00)00392-2.
- Chapter 11 Use of the Quinolones in Treatment of Bacterial MeningitisHasbun R, Quagliarello V. Chapter 11 Use of the Quinolones in Treatment of Bacterial Meningitis 2000, 325-342. DOI: 10.1016/b978-012059517-4/50012-x.
- Treatment of bacterial meningitisHasbun R, Aronin S, Quagliarello V. Treatment of bacterial meningitis Comprehensive Therapy 1999, 25: 73-81. PMID: 10091011, DOI: 10.1007/bf02889599.
- Antibiotic timing and risk stratification system in the management of community-acquired bacterial meningitisAronin S, Peduzzi P, Quagliarello V. Antibiotic timing and risk stratification system in the management of community-acquired bacterial meningitis Journal Of Osteopathic Medicine 1999, 99: 83-83. DOI: 10.7556/jaoa.1999.99.2.83.
- A prognostic rule for elderly patients admitted with community-acquired pneumoniaConte H, Chen Y, Mehal W, Phil D, Scinto J, Quagliarello V. A prognostic rule for elderly patients admitted with community-acquired pneumonia The American Journal Of Medicine 1999, 106: 20-28. PMID: 10320113, DOI: 10.1016/s0002-9343(98)00369-6.
- Treatment of Bacterial MeningitisWood A, Quagliarello V, Scheld W. Treatment of Bacterial Meningitis New England Journal Of Medicine 1997, 336: 708-716. PMID: 9041103, DOI: 10.1056/nejm199703063361007.
- Iguana-Associated Extra-Intestinal Salmonellosis in an Apparently Healthy AdultWeinstein J, Seltzer E, Farrel P, Dembry L, Quagliarello V. Iguana-Associated Extra-Intestinal Salmonellosis in an Apparently Healthy Adult Infectious Diseases In Clinical Practice 1996, 5: 513-516. DOI: 10.1097/00019048-199611000-00015.
- Prevention and Treatment of Cryptococcal Meningitis in Patients with AIDSVillanueva M, Quagliarello V. Prevention and Treatment of Cryptococcal Meningitis in Patients with AIDS CNS Drugs 1996, 5: 246-256. DOI: 10.2165/00023210-199605040-00003.
- Acute meningitis with a negative gram's stain: Clinical and management outcomes in 171 episodesElmore J, Horwitz R, Quagliarello V. Acute meningitis with a negative gram's stain: Clinical and management outcomes in 171 episodes The American Journal Of Medicine 1996, 100: 78-84. PMID: 8579091, DOI: 10.1016/s0002-9343(96)90015-7.
- Primary prevention of cryptococcal meningitis by fluconazole in HIV-infected patientsQuagliarello V, Viscoli C, Horwitz R. Primary prevention of cryptococcal meningitis by fluconazole in HIV-infected patients The Lancet 1995, 345: 548-552. PMID: 7776774, DOI: 10.1016/s0140-6736(95)90465-4.
- New perspectives on bacterial meningitis.Quagliarello V, Scheld W. New perspectives on bacterial meningitis. Clinical Infectious Diseases 1993, 17: 603-8; quiz 609-10. PMID: 8268338, DOI: 10.1093/clinids/17.4.603.
- Group B Streptococcal Meningitis in AdultsDUNNE D, QUAGLIARELLO V. Group B Streptococcal Meningitis in Adults Medicine 1993, 72: 1-10. PMID: 8426534, DOI: 10.1097/00005792-199301000-00001.
- Bacterial Meningitis: Pathogenesis, Pathophysiology, and ProgressEpstein F, Quagliarello V, Scheld W. Bacterial Meningitis: Pathogenesis, Pathophysiology, and Progress New England Journal Of Medicine 1992, 327: 864-872. PMID: 1508247, DOI: 10.1056/nejm199209173271208.
- Yeast perinephric abscess: report of a case and review.High K, Quagliarello V. Yeast perinephric abscess: report of a case and review. Clinical Infectious Diseases 1992, 15: 128-33. PMID: 1617052, DOI: 10.1093/clinids/15.1.128.
- Pathophysiology of blood-brain barrier alterations during experimental Haemophilus influenzae meningitis.Tunkel A, Wispelwey B, Quagliarello V, Rosser S, Lesse A, Hansen E, Scheld W. Pathophysiology of blood-brain barrier alterations during experimental Haemophilus influenzae meningitis. The Journal Of Infectious Diseases 1992, 165 Suppl 1: s119-20. PMID: 1588144, DOI: 10.1093/infdis/165-supplement_1-s119.
- Adjunctive therapy in bacterial meningitis--what make sense?Quagliarello V, Scheld W. Adjunctive therapy in bacterial meningitis--what make sense? Infectious Agents And Disease 1992, 1: 167-71. PMID: 1365542.
- Endovascular Infections Arising from Right-Sided Heart StructuresRemetz M, Quagliarello V. Endovascular Infections Arising from Right-Sided Heart Structures Cardiology Clinics 1992, 10: 137-149. PMID: 1739955, DOI: 10.1016/s0733-8651(18)30259-5.
- Ultrastructural localization of albumin transport across the cerebral microvasculature during experimental meningitis in the rat.Quagliarello V, Ma A, Stukenbrok H, Palade G. Ultrastructural localization of albumin transport across the cerebral microvasculature during experimental meningitis in the rat. Journal Of Experimental Medicine 1991, 174: 657-672. PMID: 1875166, PMCID: PMC2118932, DOI: 10.1084/jem.174.3.657.
- Recombinant human interleukin-1 induces meningitis and blood-brain barrier injury in the rat. Characterization and comparison with tumor necrosis factor.Quagliarello V, Wispelwey B, Long W, Scheld W. Recombinant human interleukin-1 induces meningitis and blood-brain barrier injury in the rat. Characterization and comparison with tumor necrosis factor. Journal Of Clinical Investigation 1991, 87: 1360-1366. PMID: 2010549, PMCID: PMC295174, DOI: 10.1172/jci115140.
- Potential role of host cytokines in Haemophilus influenzae lipopolysacchar ide-induced blood-brain barrier permeabilitySCHELD W, QUAGLIARELLO V, WISPELWEY B. Potential role of host cytokines in Haemophilus influenzae lipopolysacchar ide-induced blood-brain barrier permeability The Pediatric Infectious Disease Journal 1989, 8: 910. PMID: 2626302, DOI: 10.1097/00006454-198912000-00039.
- Review: Recent Advances in the Pathogenesis and Pathophysiology of Bacterial MeningitisQuagliarello V, Scheld W. Review: Recent Advances in the Pathogenesis and Pathophysiology of Bacterial Meningitis The American Journal Of The Medical Sciences 1986, 292: 306-309. PMID: 3535498, DOI: 10.1097/00000441-198611000-00010.
- Morphologic alterations of the blood-brain barrier with experimental meningitis in the rat. Temporal sequence and role of encapsulation.Quagliarello V, Long W, Scheld W. Morphologic alterations of the blood-brain barrier with experimental meningitis in the rat. Temporal sequence and role of encapsulation. Journal Of Clinical Investigation 1986, 77: 1084-1095. PMID: 3514671, PMCID: PMC424442, DOI: 10.1172/jci112407.
- Juthani-Mehta M, De Rekeneire N, Allore H, Chen S, O’Leary J, Bauer DC,. Harris TB Newman AB, Yende S, Weyant RJ, Kritchevsky S, and Quagliarello VJ. Modifiable risk factors for pneumonia requiring hospitalization among community-dwelling older adults: The Health, aging, and body composition study. J Amer Geriatr Soc 2013; 61:1111-8. Juthani-Mehta M, De Rekeneire N, Allore H, Chen S, O’Leary J, Bauer DC,. Harris TB Newman AB, Yende S, Weyant RJ, Kritchevsky S, and Quagliarello VJ. Modifiable risk factors for pneumonia requiring hospitalization among community-dwelling older adults: The Health, aging, and body composition study. J Amer Geriatr Soc 2013; 61:1111-8.