Stephen Dellaporta, PhD
Professor of Molecular, Cellular, and Developmental Biology
Research & Publications
Biography
News
Locations
Research Summary
The future of food security will increasing depend on the ability to efficiently interpret large amounts of biological and environmental data. An essential objective will be to identify and characterize useful genetic diversity and use this information to rapidly respond to emerging biotic and abiotic threats using genomic selection, genome-editing and traditional breeding approaches. To implement these technologies, advances will be needed in high throughput genomics, phenomics and predictive statistical methods as it applies to populations. My lab develops genetic and genomic methods for plant population studies together with novel computation and predictive statistical methods to identify and characterize useful genetic diversity in plants. We work with international collaborators to develop strategies to generate extensive mapping populations and associated high-throughput genomic, computational and statistical methods to identify agronomic useful variants that will be the subject of genome-editing and selection for enhanced food security.
Research Interests
Plants
Public Health Interests
Nutrition
Research Image
Variant analysis in an F2 population
Selected Publications
- Chapter 7 Hybrid Plant Systems for Breeding and Gene Confinement in Bioenergy CropsKausch A, Deresienski A, Hague J, Tilelli M, Dellaporta S, Nelson K, Li Y. Chapter 7 Hybrid Plant Systems for Breeding and Gene Confinement in Bioenergy Crops. 2013, 141-171. DOI: 10.1016/b978-0-444-53878-9.00007-2.
- Pollen Sterility—A Promising Approach to Gene Confinement and Breeding for Genetically Modified Bioenergy CropsHague J, Dellaporta S, Moreno M, Longo C, Nelson K, Kausch A. Pollen Sterility—A Promising Approach to Gene Confinement and Breeding for Genetically Modified Bioenergy Crops. Agriculture 2012, 2: 295-315. DOI: 10.3390/agriculture2040295.
- The complete mitochondrial genome of the verongid sponge Aplysina cauliformis: implications for DNA barcoding in demospongesSperling E, Rosengarten R, Moreno M, Dellaporta S. The complete mitochondrial genome of the verongid sponge Aplysina cauliformis: implications for DNA barcoding in demosponges. Hydrobiologia 2011, 687: 61-69. DOI: 10.1007/s10750-011-0879-x.
- The complete mitochondrial genome of the verongid sponge Aplysina cauliformis: implications for DNA barcoding in demospongesSperling E, Rosengarten R, Moreno M, Dellaporta S. The complete mitochondrial genome of the verongid sponge Aplysina cauliformis: implications for DNA barcoding in demosponges. 2011, 61-69. DOI: 10.1007/978-94-007-4688-6_7.
- Histocompatibility in an invertebrate is controlled by a complex of polymorphic IgSF-like genes. (170.4)Nicotra M, Dellaporta S, Buss L. Histocompatibility in an invertebrate is controlled by a complex of polymorphic IgSF-like genes. (170.4). The Journal Of Immunology 2011, 186: 170.4-170.4. DOI: 10.4049/jimmunol.186.supp.170.4.
- A Hypervariable Invertebrate AllodeterminantNicotra ML, Powell AE, Rosengarten RD, Moreno M, Grimwood J, Lakkis FG, Dellaporta SL, Buss LW. A Hypervariable Invertebrate Allodeterminant. Current Biology 2009, 19: 583-589. PMID: 19303297, PMCID: PMC2681180, DOI: 10.1016/j.cub.2009.02.040.
- Concatenated Analysis Sheds Light on Early Metazoan Evolution and Fuels a Modern “Urmetazoon” HypothesisSchierwater B, Eitel M, Jakob W, Osigus HJ, Hadrys H, Dellaporta SL, Kolokotronis SO, DeSalle R. Concatenated Analysis Sheds Light on Early Metazoan Evolution and Fuels a Modern “Urmetazoon” Hypothesis. PLOS Biology 2009, 7: e1000020. PMID: 19175291, PMCID: PMC2631068, DOI: 10.1371/journal.pbio.1000020.
- tasselseed1 Is a Lipoxygenase Affecting Jasmonic Acid Signaling in Sex Determination of MaizeAcosta I, Laparra H, Romero SP, Schmelz E, Hamberg M, Mottinger JP, Moreno MA, Dellaporta SL. tasselseed1 Is a Lipoxygenase Affecting Jasmonic Acid Signaling in Sex Determination of Maize. Science 2009, 323: 262-265. PMID: 19131630, DOI: 10.1126/science.1164645.
- The Trichoplax genome and the nature of placozoansSrivastava M, Begovic E, Chapman J, Putnam NH, Hellsten U, Kawashima T, Kuo A, Mitros T, Salamov A, Carpenter ML, Signorovitch AY, Moreno MA, Kamm K, Grimwood J, Schmutz J, Shapiro H, Grigoriev IV, Buss LW, Schierwater B, Dellaporta SL, Rokhsar DS. The Trichoplax genome and the nature of placozoans. Nature 2008, 454: 955-960. PMID: 18719581, DOI: 10.1038/nature07191.
- Embryonic chimerism does not induce tolerance in an invertebrate model organismPoudyal M, Rosa S, Powell AE, Moreno M, Dellaporta SL, Buss LW, Lakkis FG. Embryonic chimerism does not induce tolerance in an invertebrate model organism. Proceedings Of The National Academy Of Sciences Of The United States Of America 2007, 104: 4559-4564. PMID: 17360563, PMCID: PMC1838640, DOI: 10.1073/pnas.0608696104.
- Axial Patterning and Diversification in the Cnidaria Predate the Hox SystemKamm K, Schierwater B, Jakob W, Dellaporta SL, Miller DJ. Axial Patterning and Diversification in the Cnidaria Predate the Hox System. Current Biology 2006, 16: 920-926. PMID: 16563766, DOI: 10.1016/j.cub.2006.03.036.
- A low diversity of ANTP class homeobox genes in PlacozoaMonteiro A, Schierwater B, Dellaporta S, Holland P. A low diversity of ANTP class homeobox genes in Placozoa. Evolution & Development 2006, 8: 174-182. PMID: 16509895, DOI: 10.1111/j.1525-142x.2006.00087.x.
- Maize yellow stripe1 encodes a membrane protein directly involved in Fe(III) uptakeCurie C, Panaviene Z, Loulergue C, Dellaporta S, Briat J, Walker E. Maize yellow stripe1 encodes a membrane protein directly involved in Fe(III) uptake. Nature 2001, 409: 346-349. PMID: 11201743, DOI: 10.1038/35053080.
- Large-scale T-DNA mutagenesis in Arabidopsis for functional genomic analysisGalbiati M, Moreno M, Nadzan G, Zourelidou M, Dellaporta S. Large-scale T-DNA mutagenesis in Arabidopsis for functional genomic analysis. Functional & Integrative Genomics 2000, 1: 25-34. PMID: 11793219, DOI: 10.1007/s101420000007.
- Large-scale T-DNA mutagenesis inGalbiati M, Moreno M, Nadzan G, Zourelidou M, Dellaporta S. Large-scale T-DNA mutagenesis in. Functional & Integrative Genomics 2000, 1: 25. DOI: 10.1007/s101420050004.
- Cell death and cell protection genes determine the fate of pistils in maizeCalderon-Urrea A, Dellaporta S. Cell death and cell protection genes determine the fate of pistils in maize. Development 1999, 126: 435-441. PMID: 9876173, DOI: 10.1242/dev.126.3.435.
- Transposon sequences drive tissue‐specific expression of the maize regulatory gene R‐sMay B, Dellaporta S. Transposon sequences drive tissue‐specific expression of the maize regulatory gene R‐s. The Plant Journal 1998, 13: 241-247. DOI: 10.1046/j.1365-313x.1998.00010.x.
- The Ac-st2 Element of Maize Exhibits a Positive Dosage Effect and Epigenetic RegulationBrutnell T, May B, Dellaporta S. The Ac-st2 Element of Maize Exhibits a Positive Dosage Effect and Epigenetic Regulation. Genetics 1997, 147: 823-834. PMID: 9335617, PMCID: PMC1208202, DOI: 10.1093/genetics/147.2.823.
- Ectopic anthocyanin pigmentation in maize as a tool for defining interactions between homologous regulatory factorsConsonni G, Ronchi A, Pilu R, Gavazzi G, Dellaporta S, Tonelli C. Ectopic anthocyanin pigmentation in maize as a tool for defining interactions between homologous regulatory factors. Molecular Genetics And Genomics 1997, 256: 265-276. PMID: 9393451, DOI: 10.1007/s004380050569.
- Insertions of a Novel Class of Transposable Elements With a Strong Target Site Preference at the r Locus of MaizeWalker E, Eggleston W, Demopulos D, Kermicle J, Dellaporta S. Insertions of a Novel Class of Transposable Elements With a Strong Target Site Preference at the r Locus of Maize. Genetics 1997, 146: 681-693. PMID: 9178016, PMCID: PMC1208007, DOI: 10.1093/genetics/146.2.681.
- Evidence for a common sex determination mechanism for pistil abortion in maize and in its wild relative TripsacumLi D, Blakey C, Dewald C, Dellaporta S. Evidence for a common sex determination mechanism for pistil abortion in maize and in its wild relative Tripsacum. Proceedings Of The National Academy Of Sciences Of The United States Of America 1997, 94: 4217-4222. PMID: 9108132, PMCID: PMC20608, DOI: 10.1073/pnas.94.8.4217.
- liguleless1 encodes a nuclear-localized protein required for induction of ligules and auricles during maize leaf organogenesis.Moreno M, Harper L, Krueger R, Dellaporta S, Freeling M. liguleless1 encodes a nuclear-localized protein required for induction of ligules and auricles during maize leaf organogenesis. Genes & Development 1997, 11: 616-628. PMID: 9119226, DOI: 10.1101/gad.11.5.616.
- Demethylation-Induced Developmental Pleiotropy in ArabidopsisRonemus M, Galbiati M, Ticknor C, Chen J, Dellaporta S. Demethylation-Induced Developmental Pleiotropy in Arabidopsis. Science 1996, 273: 654-657. PMID: 8662558, DOI: 10.1126/science.273.5275.654.
- Leaf permease1 gene of maize is required for chloroplast development.Schultes N, Brutnell T, Allen A, Dellaporta S, Nelson T, Chen J. Leaf permease1 gene of maize is required for chloroplast development. The Plant Cell 1996, 8: 463-475. PMID: 8721750, PMCID: PMC161113, DOI: 10.1105/tpc.8.3.463.
- Transposon-mediated chromosomal rearrangements and gene duplications in the formation of the maize R-r complex.Walker E, Robbins T, Bureau T, Kermicle J, Dellaporta S. Transposon-mediated chromosomal rearrangements and gene duplications in the formation of the maize R-r complex. The EMBO Journal 1995, 14: 2350-63. PMID: 7774593, PMCID: PMC398344, DOI: 10.1002/j.1460-2075.1995.tb07230.x.
- The Sex Determination Process in MaizeDellaporta S, Calderon-Urrea A. The Sex Determination Process in Maize. Science 1994, 266: 1501-1505. PMID: 7985019, DOI: 10.1126/science.7985019.
- Somatic Inactivation and Reactivation of Ac Associated with Changes in Cytosine Methylation and Transposase ExpressionBrutnell T, Dellaporta S. Somatic Inactivation and Reactivation of Ac Associated with Changes in Cytosine Methylation and Transposase Expression. Genetics 1994, 138: 547-547. DOI: 10.1093/genetics/138.2.547.
- Somatic inactivation and reactivation of Ac associated with changes in cytosine methylation and transposase expression.Brutnell T, Dellaporta S. Somatic inactivation and reactivation of Ac associated with changes in cytosine methylation and transposase expression. Genetics 1994, 138: 213-225. PMID: 8001788, PMCID: PMC1206132, DOI: 10.1093/genetics/138.1.213.
- Gene Tagging with Ac/Ds Elements in MaizeDellaporta S, Moreno M. Gene Tagging with Ac/Ds Elements in Maize. 1994, 219-233. DOI: 10.1007/978-1-4612-2694-9_24.
- Southern Blot HybridizationDellaporta S, Moreno M. Southern Blot Hybridization. 1994, 569-572. DOI: 10.1007/978-1-4612-2694-9_99.
- Sex determination gene TASSELSEED2 of maize encodes a short-chain alcohol dehydrogenase required for stage-specific floral organ abortion Cell 74, 757–768Delong A, Calderon-Urrea A, Dellaporta S. Sex determination gene TASSELSEED2 of maize encodes a short-chain alcohol dehydrogenase required for stage-specific floral organ abortion Cell 74, 757–768. Trends In Genetics 1993, 9: 378. DOI: 10.1016/0168-9525(93)90129-6.
- Sex Determination in Flowering PlantsDellaporta S, Calderon-Urrea A. Sex Determination in Flowering Plants. The Plant Cell 1993, 5: 1241. DOI: 10.2307/3869777.
- Sex determination in flowering plants.Dellaporta S, Calderon-Urrea A. Sex determination in flowering plants. The Plant Cell 1993, 5: 1241-1251. PMID: 8281039, PMCID: PMC160357, DOI: 10.1105/tpc.5.10.1241.
- Sex determination gene TASSELSEED2 of maize encodes a short-chain alcohol dehydrogenase required for stage-specific floral organ abortionDeLong A, Calderon-Urrea A, Dellaporta S. Sex determination gene TASSELSEED2 of maize encodes a short-chain alcohol dehydrogenase required for stage-specific floral organ abortion. Cell 1993, 74: 757-768. PMID: 8358795, DOI: 10.1016/0092-8674(93)90522-r.
- Determination of paternity in dragonflies by Random Amplified Polymorphic DNA fingerprintingHADRYS H, SCHIERWATER B, DELLAPORTA S, DESALLE R, BUSS L. Determination of paternity in dragonflies by Random Amplified Polymorphic DNA fingerprinting. Molecular Ecology 1993, 2: 79-87. PMID: 8180736, DOI: 10.1111/j.1365-294x.1993.tb00002.x.
- Reconstitutional mutagenesis of the maize P gene by short-range Ac transpositions.Moreno M, Chen J, Greenblatt I, Dellaporta S. Reconstitutional mutagenesis of the maize P gene by short-range Ac transpositions. Genetics 1992, 131: 939-956. PMID: 1325389, PMCID: PMC1205104, DOI: 10.1093/genetics/131.4.939.
- Molecular analysis of Ac transposition and DNA replication.Chen J, Greenblatt I, Dellaporta S. Molecular analysis of Ac transposition and DNA replication. Genetics 1992, 130: 665-76. PMID: 1312981, PMCID: PMC1204882, DOI: 10.1093/genetics/130.3.665.
- cDNA nucleotide sequence of Sn , a regulatory gene in maizeConsonni G, Viotti A, Dellaporta S, Tonelli C. cDNA nucleotide sequence of Sn , a regulatory gene in maize. Nucleic Acids Research 1992, 20: 373-373. PMID: 1741268, PMCID: PMC310387, DOI: 10.1093/nar/20.2.373.
- Meiotic instability of the R-r complex arising from displaced intragenic exchange and intrachromosomal rearrangement.Robbins T, Walker E, Kermicle J, Alleman M, Dellaporta S. Meiotic instability of the R-r complex arising from displaced intragenic exchange and intrachromosomal rearrangement. Genetics 1991, 129: 271-283. PMID: 1682214, PMCID: PMC1204576, DOI: 10.1093/genetics/129.1.271.
- Genetic and molecular analysis of Sn, a light-inducible, tissue specific regulatory gene in maizeTonelli C, Consonni G, Dolfini S, Dellaporta S, Viotti A, Gavazzi G. Genetic and molecular analysis of Sn, a light-inducible, tissue specific regulatory gene in maize. Molecular Genetics And Genomics 1991, 225: 401-410. PMID: 1673220, DOI: 10.1007/bf00261680.
- Cell lineage analysis of the gynoecium of maize using the transposable element AcDellaporta S, Moreno M, Delong A. Cell lineage analysis of the gynoecium of maize using the transposable element Ac. Development (Cambridge, England). Supplement 1991, 113: 141-147. PMID: 1660327, DOI: 10.1242/dev.113.supplement_1.141.
- Spatial and Temporal Expression of Regulatory Genes in Zea maysTonelli C, Consonni G, Mereghetti M, Dolfini S, Dellaporta S, Viotti A, Gavazzi G. Spatial and Temporal Expression of Regulatory Genes in Zea mays. 1990, 9: 385-390. DOI: 10.1007/978-94-009-2103-0_58.
- Lc, a member of the maize R gene family responsible for tissue-specific anthocyanin production, encodes a protein similar to transcriptional activators and contains the myc-homology region.Ludwig S, Habera L, Dellaporta S, Wessler S. Lc, a member of the maize R gene family responsible for tissue-specific anthocyanin production, encodes a protein similar to transcriptional activators and contains the myc-homology region. Proceedings Of The National Academy Of Sciences Of The United States Of America 1989, 86: 7092-7096. PMID: 2674946, PMCID: PMC298000, DOI: 10.1073/pnas.86.18.7092.
- Sequential mutagenesis of a maize gene, using the transposable element DissociationKermicle J, Alleman M, Dellaporta S. Sequential mutagenesis of a maize gene, using the transposable element Dissociation. Genome 1989, 31: 712-716. DOI: 10.1139/g89-129.
- Molecular Cloning of the Maize R-nj Allele by Transposon Tagging with AcDellaporta S, Greenblatt I, Kermicle J, Hicks J, Wessler S. Molecular Cloning of the Maize R-nj Allele by Transposon Tagging with Ac. 1988, 263-282. DOI: 10.1007/978-1-4613-1037-2_12.
- Transposition of Ac From the P Locus of Maize Into Unreplicated Chromosomal SitesChen J, Greenblatt I, Dellaporta S. Transposition of Ac From the P Locus of Maize Into Unreplicated Chromosomal Sites. Genetics 1987, 117: 109-116. PMID: 2822530, PMCID: PMC1203179, DOI: 10.1093/genetics/117.1.109.
- Inactivation of the maize transposable element Activator (Ac) is associated with its DNA modification.Chomet P, Wessler S, Dellaporta S. Inactivation of the maize transposable element Activator (Ac) is associated with its DNA modification. The EMBO Journal 1987, 6: 295-302. PMID: 3034583, PMCID: PMC553394, DOI: 10.1002/j.1460-2075.1987.tb04753.x.
- Excision of Ds produces waxy proteins with a range of enzymatic activities.Wessler S, Baran G, Varagona M, Dellaporta S. Excision of Ds produces waxy proteins with a range of enzymatic activities. The EMBO Journal 1986, 5: 2427-2432. PMID: 3780665, PMCID: PMC1167135, DOI: 10.1002/j.1460-2075.1986.tb04517.x.
- The Activation of Maize Controlling ElementsDellaporta S, Chomet P. The Activation of Maize Controlling Elements. 1985, 169-216. DOI: 10.1007/978-3-7091-8765-4_10.
- Stable and unstable mutations in aberrant ratio stocks of maize.Mottinger J, Dellaporta S, Keller P. Stable and unstable mutations in aberrant ratio stocks of maize. Genetics 1984, 106: 751-67. PMID: 17246207, PMCID: PMC1202304, DOI: 10.1093/genetics/106.4.751.
- Endogenous transposable elements associated with virus infection in maize.Dellaporta S, Chomet P, Mottinger J, Wood J, Yu S, Hicks J. Endogenous transposable elements associated with virus infection in maize. Cold Spring Harbor Symposia On Quantitative Biology 1984, 49: 321-8. PMID: 6099243, DOI: 10.1101/sqb.1984.049.01.038.
- A plant DNA minipreparation: Version IIDellaporta S, Wood J, Hicks J. A plant DNA minipreparation: Version II. Plant Molecular Biology Reporter 1983, 1: 19-21. DOI: 10.1007/bf02712670.
- Liposome-mediated delivery of tobacco mosaic virus RNA into tobacco protoplasts: A sensitive assay for monitoring liposome-protoplast interactionsFraley R, Dellaporta S, Papahadjopoulos D. Liposome-mediated delivery of tobacco mosaic virus RNA into tobacco protoplasts: A sensitive assay for monitoring liposome-protoplast interactions. Proceedings Of The National Academy Of Sciences Of The United States Of America 1982, 79: 1859-1863. PMID: 16593170, PMCID: PMC346080, DOI: 10.1073/pnas.79.6.1859.
- Plasmid Studies in Crown Gall TumorigenesisDELLAPORTA S, PESANO R. Plasmid Studies in Crown Gall Tumorigenesis. 1981, 83-104. DOI: 10.1016/b978-0-12-364374-2.50011-2.