Bhaskar Roy, MBBS, MHS
Associate Professor of Neurology; Director of the Muscular Dystrophy Association adult care clinic, Neurology; Medical Director of the Electrodiagnostic Laboratory, Yale Medicine; Co-Chair of the IBM scientific interest group from IMACS, IMACS
Research & Publications
Biography
News
Research Summary
I am interested in biomarkers of idiopathic inflammatory myopathies, particularly inclusion body myositis. I also work on inflammatory neuromuscular conditions, including neuropathies, myasthenia gravis.
Coauthors
Selected Publications
- Plasmapheresis Versus Intravenous Immunoglobulin in Patients With Autoimmune Neuromuscular and Neuro-immunological ConditionsZubair A, Rethana M, Ma A, McAlpine L, Abulaban A, Munro B, Patwa H, Nowak R, Roy B. Plasmapheresis Versus Intravenous Immunoglobulin in Patients With Autoimmune Neuromuscular and Neuro-immunological Conditions. Journal Of Clinical Neuromuscular Disease 2023, 25: 11-17. PMID: 37611265, DOI: 10.1097/cnd.0000000000000439.
- Leg MRI as a Complementary Diagnostic Tool in the Assessment of Foot DropTorabi T, Zubair A, Nowak R, Tseng B, Haims A, Roy B. Leg MRI as a Complementary Diagnostic Tool in the Assessment of Foot Drop. Journal Of Clinical Neuromuscular Disease 2023, 25: 57-58. PMID: 37611274, DOI: 10.1097/cnd.0000000000000433.
- Therapeutic developments for valosin-containing protein mediated multisystem proteinopathyBoock V, Roy B, Pfeffer G, Kimonis V. Therapeutic developments for valosin-containing protein mediated multisystem proteinopathy. Current Opinion In Neurology 2023, 36: 432-440. PMID: 37678339, DOI: 10.1097/wco.0000000000001184.
- The Impact of COVID-19 on Families With Pediatric Muscular Dystrophy PatientsZubair A, Scharer K, Lembeck P, Ionita C, Roy B. The Impact of COVID-19 on Families With Pediatric Muscular Dystrophy Patients. Cureus 2023, 15: e41138. PMID: 37519528, PMCID: PMC10386847, DOI: 10.7759/cureus.41138.
- The Plasma Cell Infiltrate Populating the Muscle Tissue of Patients with Inclusion Body Myositis Features Distinct B Cell Receptor Repertoire PropertiesJiang R, Roy B, Wu Q, Mohanty S, Nowak R, Shaw A, Kleinstein S, O’Connor K. The Plasma Cell Infiltrate Populating the Muscle Tissue of Patients with Inclusion Body Myositis Features Distinct B Cell Receptor Repertoire Properties. ImmunoHorizons 2023, 7: 310-322. PMID: 37171806, PMCID: PMC10579972, DOI: 10.4049/immunohorizons.2200078.
- Imaging biomarkers in the idiopathic inflammatory myopathiesZubair A, Salam S, Dimachkie M, Machado P, Roy B. Imaging biomarkers in the idiopathic inflammatory myopathies. Frontiers In Neurology 2023, 14: 1146015. PMID: 37181575, PMCID: PMC10166883, DOI: 10.3389/fneur.2023.1146015.
- Provisional practice recommendation for the management of myopathy in VCP‐associated multisystem proteinopathyRoy B, Peck A, Evangelista T, Pfeffer G, Wang L, Diaz‐Manera J, Korb M, Wicklund M, Milone M, Freimer M, Kushlaf H, Villar‐Quiles R, Stojkovic T, Needham M, Palmio J, Lloyd T, Keung B, Mozaffar T, Weihl C, Kimonis V. Provisional practice recommendation for the management of myopathy in VCP‐associated multisystem proteinopathy. Annals Of Clinical And Translational Neurology 2023, 10: 686-695. PMID: 37026610, PMCID: PMC10187720, DOI: 10.1002/acn3.51760.
- A New Insight in Causal Pathways Following Subcortical Stroke: From Correlation to Causation.Roy B, Marshall RS. A New Insight in Causal Pathways Following Subcortical Stroke: From Correlation to Causation. Neurology 2022 PMID: 36307227, DOI: 10.1212/WNL.0000000000201648.
- Heterogeneity of Acetylcholine Receptor Autoantibody–Mediated Complement Activity in Patients With Myasthenia GravisObaid AH, Zografou C, Vadysirisack DD, Munro-Sheldon B, Fichtner ML, Roy B, Philbrick WM, Bennett JL, Nowak RJ, O'Connor KC. Heterogeneity of Acetylcholine Receptor Autoantibody–Mediated Complement Activity in Patients With Myasthenia Gravis. Neurology Neuroimmunology & Neuroinflammation 2022, 9: e1169. PMID: 35473886, PMCID: PMC9128035, DOI: 10.1212/nxi.0000000000001169.
- Reliability of patient self-reports to clinician-assigned functional scores of inclusion body myositisRoy B, Zubair A, Petschke K, O'Connor KC, Paltiel AD, Nowak RJ. Reliability of patient self-reports to clinician-assigned functional scores of inclusion body myositis. Journal Of The Neurological Sciences 2022, 436: 120228. PMID: 35344793, DOI: 10.1016/j.jns.2022.120228.
- Clinical Reasoning: A 73-Year-Old Woman With Episodic Dysarthria and Horizontal Binocular DiplopiaBower AS, Fisayo A, Baehring JM, Roy B. Clinical Reasoning: A 73-Year-Old Woman With Episodic Dysarthria and Horizontal Binocular Diplopia. Neurology 2022, 98: 767-772. PMID: 35264421, DOI: 10.1212/wnl.0000000000200347.
- Development of a standard of care for patients with valosin-containing protein associated multisystem proteinopathyKorb M, Peck A, Alfano LN, Berger KI, James MK, Ghoshal N, Healzer E, Henchcliffe C, Khan S, Mammen PPA, Patel S, Pfeffer G, Ralston SH, Roy B, Seeley WW, Swenson A, Mozaffar T, Weihl C, Kimonis V. Development of a standard of care for patients with valosin-containing protein associated multisystem proteinopathy. Orphanet Journal Of Rare Diseases 2022, 17: 23. PMID: 35093159, PMCID: PMC8800193, DOI: 10.1186/s13023-022-02172-5.
- Ulnar neuropathy from accessory epitrochlearis anconeus muscleZubair AS, Wang A, Roy B. Ulnar neuropathy from accessory epitrochlearis anconeus muscle. Neurological Sciences 2021, 43: 2165-2166. PMID: 34786630, DOI: 10.1007/s10072-021-05713-1.
- Influenza vaccination in autoimmune neuromuscular diseases: A survey of current practices and perceptionsRoy B, Litchman T, Torabi T, Nowak RJ. Influenza vaccination in autoimmune neuromuscular diseases: A survey of current practices and perceptions. Muscle & Nerve 2021, 63: 918-923. PMID: 33711167, DOI: 10.1002/mus.27224.
- Myotonic Muscular Dystrophy Type 2 in CT, USA: A Single-Center Experience With 50 Patients.Roy B, Wu Q, Whitaker CH, Felice KJ. Myotonic Muscular Dystrophy Type 2 in CT, USA: A Single-Center Experience With 50 Patients. Journal Of Clinical Neuromuscular Disease 2021, 22: 135-146. PMID: 33595997, DOI: 10.1097/CND.0000000000000340.
- Electronic health record derived-impact of COVID-19 on myasthenia gravisRoy B, Kovvuru S, Nalleballe K, Onteddu SR, Nowak RJ. Electronic health record derived-impact of COVID-19 on myasthenia gravis. Journal Of The Neurological Sciences 2021, 423: 117362. PMID: 33639420, PMCID: PMC7895699, DOI: 10.1016/j.jns.2021.117362.
- Challenges for Treatment Trials of Inclusion Body Myositis.Roy B, Griggs RC. Challenges for Treatment Trials of Inclusion Body Myositis. Neurology 2021, 96: 555-556. PMID: 33597288, DOI: 10.1212/wnl.0000000000011628.
- Advances in Treatments in Muscular Dystrophies and Motor Neuron Disorders.Roy B, Griggs R. Advances in Treatments in Muscular Dystrophies and Motor Neuron Disorders. Neurologic Clinics 2021, 39: 87-112. PMID: 33223091, DOI: 10.1016/j.ncl.2020.09.005.
- Guillain-Barré Syndrome as a Complication of COVID-19Zubair AS, Zubair AS, Desai K, Abulaban A, Roy B. Guillain-Barré Syndrome as a Complication of COVID-19. Cureus 2021, 13: e12695. PMID: 33614303, PMCID: PMC7883582, DOI: 10.7759/cureus.12695.
- Bleeding with vascular endothelial growth factor tyrosine kinase inhibitor: A network meta-analysisDas A, Mahapatra S, Bandyopadhyay D, Samanta S, Chakraborty S, Philpotts LL, Jahangir E, Roy B. Bleeding with vascular endothelial growth factor tyrosine kinase inhibitor: A network meta-analysis. Critical Reviews In Oncology/Hematology 2020, 157: 103186. PMID: 33309571, DOI: 10.1016/j.critrevonc.2020.103186.
- Immunosuppression in chronic autoimmune neurological disorders during the COVID-19 pandemicKovvuru S, Nalleballe K, Onteddu SR, Sharma R, Jasti M, Kapoor N, Veerapaneni K, Yadala S, Dandu V, Archer R, Nowak RJ, Roy B. Immunosuppression in chronic autoimmune neurological disorders during the COVID-19 pandemic. Journal Of The Neurological Sciences 2020, 420: 117230. PMID: 33256952, PMCID: PMC7837234, DOI: 10.1016/j.jns.2020.117230.
- Risk of coronavirus disease 2019 (COVID-19) from hospital admission during the pandemicNalleballe K, Siddamreddy S, Kovvuru S, Veerapaneni P, Roy B, Onteddu SR. Risk of coronavirus disease 2019 (COVID-19) from hospital admission during the pandemic. Infection Control And Hospital Epidemiology 2020, 42: 1285-1286. PMID: 33028457, PMCID: PMC7578623, DOI: 10.1017/ice.2020.1249.
- Eculizumab in Acute Motor Axonal Neuropathy: An Ethical Application of an Off-Label Indication.Roy B, Nowak RJ. Eculizumab in Acute Motor Axonal Neuropathy: An Ethical Application of an Off-Label Indication. Journal Of Clinical Neuromuscular Disease 2020, 22: 63-64. PMID: 32833730, DOI: 10.1097/CND.0000000000000295.
- COVID-19 in patients with neurological disordersOnteddu SR, Nalleballe K, Siddamreddy S, Jasti M, Kovvuru S, Dandu V, Roy B. COVID-19 in patients with neurological disorders. Brain Behavior & Immunity - Health 2020, 8: 100131. PMID: 32864634, PMCID: PMC7445184, DOI: 10.1016/j.bbih.2020.100131.
- Reply to: What is the pattern of the neuropathy associated with anti‐FGFR3 antibodies?Roy B, Kovvuru S, Castillo Y, Huttner A, Nowak R. Reply to: What is the pattern of the neuropathy associated with anti‐FGFR3 antibodies? European Journal Of Neurology 2020, 27: e59-e59. PMID: 32503081, DOI: 10.1111/ene.14381.
- Teleneurology during the COVID-19 pandemic: A step forward in modernizing medical careRoy B, Nowak RJ, Roda R, Khokhar B, Patwa HS, Lloyd T, Rutkove SB. Teleneurology during the COVID-19 pandemic: A step forward in modernizing medical care. Journal Of The Neurological Sciences 2020, 414: 116930. PMID: 32460041, PMCID: PMC7241381, DOI: 10.1016/j.jns.2020.116930.
- Clinical Effects of the Self-administered Subcutaneous Complement Inhibitor Zilucoplan in Patients With Moderate to Severe Generalized Myasthenia GravisHoward JF, Nowak RJ, Wolfe GI, Freimer ML, Vu TH, Hinton JL, Benatar M, Duda PW, MacDougall JE, Farzaneh-Far R, Kaminski HJ, Barohn R, Dimachkie M, Pasnoor M, Farmakidis C, Liu T, Colgan S, Benatar M, Bertorini T, Pillai R, Henegar R, Bromberg M, Gibson S, Janecki T, Freimer M, Elsheikh B, Matisak P, Genge A, Guidon A, David W, Habib A, Mathew V, Mozaffar T, Hinton J, Hewitt W, Barnett D, Sullivan P, Ho D, Howard J, Traub R, Chopra M, Kaminski H, Aly R, Bayat E, Abu-Rub M, Khan S, Lange D, Holzberg S, Khatri B, Lindman E, Olapo T, Sershon L, Lisak R, Bernitsas E, Jia K, Malik R, Lewis-Collins T, Nicolle M, Nowak R, Sharma A, Roy B, Nye J, Pulley M, Berger A, Shabbir Y, Sachdev A, Patterson K, Siddiqi Z, Sivak M, Bratton J, Small G, Kohli A, Fetter M, Vu T, Lam L, Harvey B, Wolfe G, Silvestri N, Patrick K, Zakalik K, Duda P, MacDougall J, Farzaneh-Far R, Pontius A, Hoarty M. Clinical Effects of the Self-administered Subcutaneous Complement Inhibitor Zilucoplan in Patients With Moderate to Severe Generalized Myasthenia Gravis. JAMA Neurology 2020, 77: 582-592. PMID: 32065623, PMCID: PMC7042797, DOI: 10.1001/jamaneurol.2019.5125.
- Exploring outcomes and characteristics of myasthenia gravis: Rationale, aims and design of registry – The EXPLORE-MG registryAnil R, Kumar A, Alaparthi S, Sharma A, Nye JL, Roy B, O'Connor KC, Nowak RJ. Exploring outcomes and characteristics of myasthenia gravis: Rationale, aims and design of registry – The EXPLORE-MG registry. Journal Of The Neurological Sciences 2020, 414: 116830. PMID: 32388060, DOI: 10.1016/j.jns.2020.116830.
- Clinical characteristics of fibroblast growth factor receptor 3 antibody‐related polyneuropathy: a retrospective studyKovvuru S, Cardenas Y, Huttner A, Nowak R, Roy B. Clinical characteristics of fibroblast growth factor receptor 3 antibody‐related polyneuropathy: a retrospective study. European Journal Of Neurology 2020, 27: 1310-1318. PMID: 32068339, DOI: 10.1111/ene.14180.
- Differential response to rituximab in anti-AChR and anti-MuSK positive myasthenia gravis patients: a single-center retrospective studyLitchman T, Roy B, Kumar A, Sharma A, Njike V, Nowak RJ. Differential response to rituximab in anti-AChR and anti-MuSK positive myasthenia gravis patients: a single-center retrospective study. Journal Of The Neurological Sciences 2020, 411: 116690. PMID: 32028072, DOI: 10.1016/j.jns.2020.116690.
- Electrical impedance myography as a biomarker of inclusion body myositis: A cross-sectional studyRoy B, Rutkove SB, Nowak RJ. Electrical impedance myography as a biomarker of inclusion body myositis: A cross-sectional study. Clinical Neurophysiology 2019, 131: 368-371. PMID: 31865137, DOI: 10.1016/j.clinph.2019.10.030.
- Clinical Reasoning: Progressive proximal weakness in a 56-year-old man with bone painTorabi T, Huttner A, Nowak RJ, Roy B. Clinical Reasoning: Progressive proximal weakness in a 56-year-old man with bone pain. Neurology 2019, 93: 939-944. PMID: 31740511, DOI: 10.1212/wnl.0000000000008535.
- Neuropathy with vascular endothelial growth factor receptor tyrosine kinase inhibitors: A meta-analysis.Roy B, Das A, Ashish K, Bandyopadhyay D, Maiti A, Chakraborty S, Stone ME, Philpotts LL, Nowak RJ, Patwa HS. Neuropathy with vascular endothelial growth factor receptor tyrosine kinase inhibitors: A meta-analysis. Neurology 2019, 93: e143-e148. PMID: 31167931, DOI: 10.1212/wnl.0000000000007743.
- Exploring the relationship between electrical impedance myography and quantitative ultrasound parameters in Duchenne muscular dystrophyRoy B, Darras BT, Zaidman CM, Wu JS, Kapur K, Rutkove SB. Exploring the relationship between electrical impedance myography and quantitative ultrasound parameters in Duchenne muscular dystrophy. Clinical Neurophysiology 2019, 130: 515-520. PMID: 30772764, PMCID: PMC6411427, DOI: 10.1016/j.clinph.2019.01.018.
- Comparison of treatment options for depression in heart failure: A network meta-analysisDas A, Roy B, Schwarzer G, Silverman MG, Ziegler O, Bandyopadhyay D, Philpotts LL, Sinha S, Blumenthal JA, Das S. Comparison of treatment options for depression in heart failure: A network meta-analysis. Journal Of Psychiatric Research 2018, 108: 7-23. PMID: 30419488, DOI: 10.1016/j.jpsychires.2018.10.007.
- Clinical ReasoningRoy B, Raynor E. Clinical Reasoning. Neurology 2018, 90: e172-e176. PMID: 29311375, DOI: 10.1212/wnl.0000000000004808.
- Motor Neuron DiseaseRoy B, Darras B. Motor Neuron Disease. 2017, 199-220. DOI: 10.1007/978-3-319-61361-1_16.
- Clinical Reasoning: A 14-year-old boy with fatigue and episodic worsening of weakness.Roy B, Chahin N. Clinical Reasoning: A 14-year-old boy with fatigue and episodic worsening of weakness. Neurology 2017, 88: e96-e100. PMID: 28289174, DOI: 10.1212/WNL.0000000000003718.
- Comparison of Initial Vasopressors Used for Delayed Cerebral Ischemia after Aneurysmal Subarachnoid Hemorrhage.Roy B, McCullough LD, Dhar R, Grady J, Wang YB, Brown RJ. Comparison of Initial Vasopressors Used for Delayed Cerebral Ischemia after Aneurysmal Subarachnoid Hemorrhage. Cerebrovascular Diseases (Basel, Switzerland) 2017, 43: 266-271. PMID: 28319954, DOI: 10.1159/000458536.
- Teaching Images in Headache: Cavernous Sinus Aspergillosis.Roy B, Grosberg BM. Teaching Images in Headache: Cavernous Sinus Aspergillosis. Headache 2016, 56: 1653-1655. PMID: 27753079, DOI: 10.1111/head.12964.
- Rheumatoid Meningitis Presenting With Multiple Strokelike Episodes.Roy B, Uphoff DF, Silverman IE. Rheumatoid Meningitis Presenting With Multiple Strokelike Episodes. JAMA Neurology 2015, 72: 1073-6. PMID: 26368353, DOI: 10.1001/jamaneurol.2015.1105.
- Sequential application of a cytotoxic nanoparticle and a PI3K inhibitor enhances antitumor efficacy.Pandey A, Kulkarni A, Roy B, Goldman A, Sarangi S, Sengupta P, Phipps C, Kopparam J, Oh M, Basu S, Kohandel M, Sengupta S. Sequential application of a cytotoxic nanoparticle and a PI3K inhibitor enhances antitumor efficacy. Cancer Research 2014, 74: 675-685. PMID: 24121494, PMCID: PMC3946433, DOI: 10.1158/0008-5472.CAN-12-3783.
- Effect of rotating acoustic stimulus on heart rate variability in healthy adults.Roy B, Choudhuri R, Pandey A, Bandopadhyay S, Sarangi S, Kumar Ghatak S. Effect of rotating acoustic stimulus on heart rate variability in healthy adults. The Open Neurology Journal 2012, 6: 71-7. PMID: 23091566, PMCID: PMC3474995, DOI: 10.2174/1874205X01206010071.