2011
Stool-fermented Plantago ovata husk induces apoptosis in colorectal cancer cells independently of molecular phenotype
Sohn VR, Giros A, Xicola RM, Fluvià L, Grzybowski M, Anguera A, Llor X. Stool-fermented Plantago ovata husk induces apoptosis in colorectal cancer cells independently of molecular phenotype. British Journal Of Nutrition 2011, 107: 1591-1602. PMID: 22018732, DOI: 10.1017/s0007114511004910.Peer-Reviewed Original ResearchMeSH KeywordsAntineoplastic Agents, PhytogenicApoptosisBacteria, AnaerobicBcl-2 Homologous Antagonist-Killer ProteinBcl-X ProteinCell Line, TumorColorectal NeoplasmsFatty Acids, VolatileFecesFermentationGene Expression ProfilingGene Expression Regulation, NeoplasticHumansMembrane Potential, MitochondrialNeoplasm ProteinsOligonucleotide Array Sequence AnalysisPlant EpidermisPlantagoRNA, MessengerSeedsConceptsMolecular phenotypesExtrinsic pathwayDeath receptor-mediated apoptosisDeath domain proteinActivator of caspaseMitochondrial membrane depolarisationApoptosis-inducing factorReceptor-mediated apoptosisInhibitor of apoptosisLoVo cellsRegulation of inhibitorAdenomatous polyposis coliTNF-α ligandDomain proteinsMetastatic cell linesPro-apoptotic environmentCaspase activatorsCRC cellsApoptotic proteaseDifferent molecular phenotypesPro-apoptotic effectsDeath receptorsPlantago ovata huskApoptosis survivinIntrinsic pathway
2009
S1271 Plantago Ovata Husk Regulates Cell Cycle Progression and Wnt Signaling Pathway, Crucial Elements Implicated in Colorectal Carcinogenesis
Sapoznik V, Grzybowski M, Xicola R, Doyle B, Grzybowski J, Martinez T, Anguera A, Llor X. S1271 Plantago Ovata Husk Regulates Cell Cycle Progression and Wnt Signaling Pathway, Crucial Elements Implicated in Colorectal Carcinogenesis. Gastroenterology 2009, 136: a-226. DOI: 10.1016/s0016-5085(09)61020-9.Peer-Reviewed Original ResearchS1272 Differential Regulation of Apoptosis Induction By Plantago Ovata Husk in Colorectal Cancer Cells. Induction of the TNF-Alpha Apoptosis Cascade in Metastatic Cells
Grzybowski M, Sapoznik V, Xicola R, Doyle B, Grzybowski J, Martinez T, Anguera A, Llor X. S1272 Differential Regulation of Apoptosis Induction By Plantago Ovata Husk in Colorectal Cancer Cells. Induction of the TNF-Alpha Apoptosis Cascade in Metastatic Cells. Gastroenterology 2009, 136: a-226. DOI: 10.1016/s0016-5085(09)61021-0.Peer-Reviewed Original Research