2021
Dickkopf-2 regulates the stem cell marker LGR5 in colorectal cancer via HNF4α1
Shin JH, Jeong J, Choi J, Lim J, Dinesh RK, Braverman J, Hong JY, Maher SE, Vesely M, Kim W, Koo JH, Tang W, Wu D, Blackburn HN, Xicola RM, Llor X, Yilmaz O, Choi JM, Bothwell ALM. Dickkopf-2 regulates the stem cell marker LGR5 in colorectal cancer via HNF4α1. IScience 2021, 24: 102411. PMID: 33997693, PMCID: PMC8099562, DOI: 10.1016/j.isci.2021.102411.Peer-Reviewed Original ResearchColorectal cancerDickkopf-2Colitis-associated cancerColorectal cancer stemnessStem cell marker Lgr5Colonic epithelial cellsAggressive progressionCancer stemnessLGR5 expressionColonic organoidsCancerEpithelial cellsCell marker genesStem cell marker genesSignificant increaseGenetic depletionWnt ligandsStem cellsProgressionLgr5StemnessCellsExpressionSequential mutationsMutations
2009
S1272 Differential Regulation of Apoptosis Induction By Plantago Ovata Husk in Colorectal Cancer Cells. Induction of the TNF-Alpha Apoptosis Cascade in Metastatic Cells
Grzybowski M, Sapoznik V, Xicola R, Doyle B, Grzybowski J, Martinez T, Anguera A, Llor X. S1272 Differential Regulation of Apoptosis Induction By Plantago Ovata Husk in Colorectal Cancer Cells. Induction of the TNF-Alpha Apoptosis Cascade in Metastatic Cells. Gastroenterology 2009, 136: a-226. DOI: 10.1016/s0016-5085(09)61021-0.Peer-Reviewed Original Research