2021
VZV myelitis with secondary HIV CSF escape
Weiss JJ, Spudich S, Barakat L. VZV myelitis with secondary HIV CSF escape. BMJ Case Reports 2021, 14: e241738. PMID: 34187795, PMCID: PMC8245447, DOI: 10.1136/bcr-2021-241738.Peer-Reviewed Case Reports and Technical NotesConceptsVaricella-zoster virusCSF escapeVZV myelitisSkin lesionsCerebrospinal fluidCSF HIV viral loadRight upper extremity weaknessCentral nervous system infectionSubsequent oral therapyUpper extremity weaknessHIV viral loadNervous system infectionVesicular skin lesionsCopies/mLDirect fluorescent antibody testingFluorescent antibody testingIntravenous acyclovirVZV PCRExtremity weaknessOral therapyRare complicationSystem infectionAtypical presentationImmunosuppressed patientsVZV infection
2018
Safety of lumbar puncture procedure in an international research setting during acute HIV infection
Chan P, Hellmuth J, Colby D, Kroon E, Sacdalan C, Fletcher J, Patel P, Pinyakorn S, Valcour V, Ananworanich J, Spudich S. Safety of lumbar puncture procedure in an international research setting during acute HIV infection. Journal Of Virus Eradication 2018, 4: 16-20. PMID: 29568548, PMCID: PMC5851179, DOI: 10.1016/s2055-6640(20)30236-3.Peer-Reviewed Original ResearchPost-lumbar puncture headacheAcute HIV infectionCombination antiretroviral therapyBody mass indexLumbar punctureHIV infectionAtraumatic needlesCerebrospinal fluidCSF HIV viral loadHigher body mass indexT-lymphocyte countsAcute retroviral syndromeHIV viral loadFrequency of PPHCerebrospinal fluid volumeLumbar puncture procedureCART initiationAntiretroviral therapyLymphocyte countMass indexViral loadPuncture headacheClinical recordsLongitudinal visitsSubgroup analysis
2005
Cerebrospinal fluid HIV infection and pleocytosis: Relation to systemic infection and antiretroviral treatment
Spudich SS, Nilsson AC, Lollo ND, Liegler TJ, Petropoulos CJ, Deeks SG, Paxinos EE, Price RW. Cerebrospinal fluid HIV infection and pleocytosis: Relation to systemic infection and antiretroviral treatment. BMC Infectious Diseases 2005, 5: 98. PMID: 16266436, PMCID: PMC1299327, DOI: 10.1186/1471-2334-5-98.Peer-Reviewed Original ResearchConceptsAIDS dementia complexCSF HIV viral loadCSF viral loadAntiretroviral therapyHIV viral loadViral loadCD4 countCerebrospinal fluidCSF pleocytosisCSF infectionHIV infectionSystemic infectionHIV RNACSF WBCNeurological performanceCSF white blood cell countResultsIn cross-sectional analysisWhite blood cell countBlood CD4 countCNS HIV infectionCSF HIV RNAHigher CSF WBCLow CD4 countPersistent plasma viremiaHIV RNA levels