2023
Interactive association of posttraumatic stress disorder, apolipoprotein ε4 genotype, and age on cognitive functioning
Lawrence K, Rippey C, Welikson B, Pietrzak R, Adams T. Interactive association of posttraumatic stress disorder, apolipoprotein ε4 genotype, and age on cognitive functioning. International Journal Of Geriatric Psychiatry 2023, 38: e5888. PMID: 36757293, PMCID: PMC10168127, DOI: 10.1002/gps.5888.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderThree-way interactionCognitive functioningStress disorderOlder participantsTreatment of PTSDMain effectProbable posttraumatic stress disorderAge-related cognitive impairmentAPOE ε4U.S. military veteransApolipoprotein ε4 genotypeCognitive deficitsPsychomotor performanceAge-related associationsInteractive associationsVeterans StudyMilitary veteransCognitive impairmentPreliminary evidenceTwo-way interactionAPM performanceΕ4 carriersAnalysis of covarianceFunctioning
2022
Post-traumatic Stress Disorder
Merians A, Spiller T, Harpaz-Rotem I, Krystal J, Pietrzak R. Post-traumatic Stress Disorder. Medical Clinics Of North America 2022, 107: 85-99. PMID: 36402502, DOI: 10.1016/j.mcna.2022.04.003.Peer-Reviewed Original ResearchConceptsPost-traumatic stress disorderStress disorderCognitive processing therapyCognitive behavioral therapyEye movement desensitizationEvidence-based psychotherapiesTraumatic eventsBehavioral therapyNegative alterationsFirst-line pharmacologic treatmentStructured interviewsFirst-line treatmentNonpsychiatric settingsLarge bodyPharmacologic treatmentReuptake inhibitorsCognitionDisordersArousalTherapeutic interventionsMoodPsychotherapyAvoidanceTherapyIntervention