2024
Prevalence, Correlates, and Burden of Subthreshold PTSD in US Veterans.
Fischer I, Na P, Harpaz-Rotem I, Marx B, Pietrzak R. Prevalence, Correlates, and Burden of Subthreshold PTSD in US Veterans. The Journal Of Clinical Psychiatry 2024, 85 PMID: 39480145, DOI: 10.4088/jcp.24m15465.Peer-Reviewed Original ResearchConceptsSubthreshold posttraumatic stress disorderPosttraumatic stress disorderPosttraumatic stress disorder symptom clustersLifetime psychiatric disordersUS veteransUS military veteransSymptom-related distressStress disorderPsychiatric disordersSymptom clustersTreating veteransCriterion AMilitary veteransTraumatic eventsCognitive functionWorking case definitionMental healthCriterion FFunctional impairmentVeteransNationally representative sampleFunctional correlatesDisordersElevated oddsGreater oddsPsychological Factors, Physical Conditions, and Functioning Among US Veterans
Fischer I, Na P, Feldman D, Krist A, Kudler H, Jeste D, Pietrzak R. Psychological Factors, Physical Conditions, and Functioning Among US Veterans. JAMA Network Open 2024, 7: e2427382. PMID: 39120905, PMCID: PMC11316230, DOI: 10.1001/jamanetworkopen.2024.27382.Peer-Reviewed Original ResearchFunctional significance of posttraumatic growth in U.S. military veterans
Gower T, Fischer I, Tsai J, Kang H, Na P, Tedeschi R, Pietrzak R. Functional significance of posttraumatic growth in U.S. military veterans. Journal Of Affective Disorders 2024, 356: 267-273. PMID: 38614442, DOI: 10.1016/j.jad.2024.04.046.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderPosttraumatic stress disorder symptomsPosttraumatic growthPsychosocial functioningTraumatic eventsTrauma-exposed U.S. veteransNational Health and ResilienceMale veteran samplePost-trauma functioningPattern of findingsRetrospective self-reportsU.S. military veteransVeteran sampleStress disorderVeterans StudyExamined relationsCross-sectional designMilitary veteransNationally representative sampleU.S. veteransAssociated with functionsPhysical functionClinical interventionsPsychosocial characteristicsVeteransDifferential associations of adverse childhood experiences and mental health outcomes in U.S. military veterans
Slavin A, Fischer I, Pietrzak R. Differential associations of adverse childhood experiences and mental health outcomes in U.S. military veterans. Journal Of Psychiatric Research 2024, 172: 261-265. PMID: 38412789, DOI: 10.1016/j.jpsychires.2024.02.040.Peer-Reviewed Original ResearchConceptsAdverse childhood experiencesMental health outcomesChildhood traumaEmotional neglectMilitary veteransChildhood experiencesNational Health and ResiliencePrevalence of childhood traumaAssociated with adverse mental health outcomesHealth outcomesChildhood emotional neglectPosttraumatic stress disorderEffects of adverse childhood experiencesU.S. military veteransAssociation of adverse childhood experiencesSample of veteransAdverse mental health outcomesAdverse mental health effectsStress disorderGeneralized anxietyPopulation-based sample of veteransVeterans StudySuicidal thoughtsPopulation-based sampleIndividual adverse childhood experiencesProblematic Alcohol Use Trajectories in U.S. Military Veterans during a Public Health Crisis: Results from a 3-year, Nationally Representative, Longitudinal Study
Na P, Fischer I, Petrakis I, Pietrzak R. Problematic Alcohol Use Trajectories in U.S. Military Veterans during a Public Health Crisis: Results from a 3-year, Nationally Representative, Longitudinal Study. Psychiatric Quarterly 2024, 95: 157-171. PMID: 38319532, PMCID: PMC11521206, DOI: 10.1007/s11126-024-10067-w.Peer-Reviewed Original ResearchConceptsDrug use disordersProblematic alcohol useAlcohol use trajectoriesLow social supportAdverse childhood experiencesAlcohol useGreater household incomeSocial supportUS veteransLongitudinal studyNational Health and ResilienceLatent growth mixture modelingU.S. military veteransHousehold incomeGrowth mixture modelingNon-household membersCOVID-19 pandemicVeterans StudyUse disorderMilitary veteransChildhood experiencesPublic health crisisPsychosocial characteristicsPrevention effortsVeteransGeneralized anxiety and mild anxiety symptoms in U.S. military veterans: Prevalence, characteristics, and functioning
Macdonald-Gagnon G, Stefanovics E, Potenza M, Pietrzak R. Generalized anxiety and mild anxiety symptoms in U.S. military veterans: Prevalence, characteristics, and functioning. Journal Of Psychiatric Research 2024, 171: 263-270. PMID: 38325107, DOI: 10.1016/j.jpsychires.2024.02.013.Peer-Reviewed Original ResearchConceptsGeneralized anxiety disorderMild anxiety symptomsAnxiety symptomsMilitary veteransU.S. veteransCorrelates of generalized anxiety disorderCorrelates of anxiety symptomsAnxiety symptom severityU.S. military veteransAnxiety disordersGeneralized anxietyPoor mental healthSuicidal thoughtsSymptom severityMental disordersExcessive anxietyAnxietyMagnitude associationsMental healthFunctional impairmentVeteransFunctional correlatesClinical samplesNationally representative sampleSymptomsThe mediating role of social support in associations between childhood adversity, military sexual trauma, and homelessness in a nationally representative sample of US veterans
Bulanchuk N, Edwards E, Pietrzak R, Tsai J. The mediating role of social support in associations between childhood adversity, military sexual trauma, and homelessness in a nationally representative sample of US veterans. Journal Of Community Psychology 2024, 52: 399-414. PMID: 38289875, DOI: 10.1002/jcop.23105.Peer-Reviewed Original ResearchConceptsMilitary sexual traumaAdverse childhood experiencesLifetime homelessnessSocial supportSexual traumaNationally representative sampleHistory of military sexual traumaCorrelates of homelessnessAvailability of social supportPerceived social supportInterpersonal social supportLow social supportRepresentative sampleChildhood adversityHomelessnessFemale veteransChildhood experiencesCommunity integrationMale counterpartsPath analysisVeteransUS veteransTrauma ratesNationalCorrelation analysisFirearm storage practices among military veterans in the United States: Findings from a nationally representative survey
Nichter B, Hill M, Fischer I, Panza K, Kline A, Na P, Norman S, Rowcliffe M, Pietrzak R. Firearm storage practices among military veterans in the United States: Findings from a nationally representative survey. Journal Of Affective Disorders 2024, 351: 82-89. PMID: 38280567, DOI: 10.1016/j.jad.2024.01.179.Peer-Reviewed Original ResearchMeSH KeywordsCross-Sectional StudiesDepressive Disorder, MajorFirearmsHumansSuicideUnited StatesVeteransConceptsFirearm storage practicesContemporary population-based dataNational Health and ResiliencePromote safe firearm storageTrauma exposureAssociated with increased risk of suicidePopulation-based dataCross-sectional designStorage of firearmsAssociated with increased riskRisk of suicideNationally representative surveyDrug use disordersHealthcare professionalsSociodemographic characteristicsVeterans StudyFirearm storageTraumatic brain injuryU.S. veteransService membersMilitary veteransStorage practicesTraining initiativesVeteransRisk statusFunctional correlates of a novel 8-factor model of PTSD in U.S. military veterans: Results from the National Health and Resilience in Veterans Study
Stiltner B, Fischer I, Duek O, Polimanti R, Harpaz-Rotem I, Pietrzak R. Functional correlates of a novel 8-factor model of PTSD in U.S. military veterans: Results from the National Health and Resilience in Veterans Study. Journal Of Psychiatric Research 2024, 171: 69-74. PMID: 38244335, DOI: 10.1016/j.jpsychires.2024.01.017.Peer-Reviewed Original ResearchConceptsModels of posttraumatic stress disorderPosttraumatic stress disorderNational Health and ResilienceU.S. military veteransArousal symptomsSuicidal ideationVeterans StudyCurrent depressionSymptom clustersMilitary veteransPosttraumatic stress disorder symptom clustersPosttraumatic stress disorder symptomsPosttraumatic Stress Disorder ChecklistAnxious arousal symptomsDysphoric arousal symptomsIntrusive symptom clustersOdds of suicidal ideationFunctional correlatesMulti-faceted disorderExternalizing behavioral symptomsAssociated with lower oddsAssociated with higher oddsSymptom structureAvoidance symptomsDSM-5
2023
Functional decline during the COVID‐19 pandemic among U.S. military veterans: Results from the National Health and Resilience in Veterans Study
Morse J, Fischer I, Na P, Afari N, Pietrzak R. Functional decline during the COVID‐19 pandemic among U.S. military veterans: Results from the National Health and Resilience in Veterans Study. International Journal Of Geriatric Psychiatry 2023, 38: e6040. PMID: 38072628, DOI: 10.1002/gps.6040.Peer-Reviewed Original ResearchConceptsAdverse childhood experiencesFunctional declineU.S. military veteransGreater adverse childhood experiencesNational HealthPhysical functioningVeterans StudyIdentification of veteransSubstantial health problemPhysical functional declineMilitary veteransMental functioningU.S. adult populationStress symptomsStrongest correlatePrevalence of veteransProtective psychosocial characteristicsMultivariable analysisPosttraumatic stress symptomsHealth problemsU.S. veteransAdult populationImprovement 1Coronavirus diseaseOlder ageWell-Being of US Military Veterans
Na P, Fischer I, Krist A, Kudler H, Jeste D, Pietrzak R. Well-Being of US Military Veterans. JAMA Network Open 2023, 6: e2346709. PMID: 38060229, PMCID: PMC10704281, DOI: 10.1001/jamanetworkopen.2023.46709.Peer-Reviewed Original ResearchEvaluating a novel 8-factor dimensional model of PTSD in U.S. military veterans: Results from the National Health and Resilience in Veterans Study
Stiltner B, Fischer I, Duek O, Polimanti R, Harpaz-Rotem I, Pietrzak R. Evaluating a novel 8-factor dimensional model of PTSD in U.S. military veterans: Results from the National Health and Resilience in Veterans Study. Journal Of Affective Disorders 2023, 346: 303-307. PMID: 37979626, DOI: 10.1016/j.jad.2023.11.041.Peer-Reviewed Original ResearchConceptsIndex traumaPTSD symptomsNational HealthPosttraumatic stress disorder (PTSD) symptomsVeterans StudyMilitary veteransTrauma-exposed populationsClinician-administered interviewU.S. military veteransConfirmatory factor analysisDSM-5 modelStrong significant associationTrauma exposureIntrusive symptomsDisorder symptomsCombat exposureHigh riskU.S. veteransDSM-5Significant associationSymptomsInterpersonal violenceFactor analysisPTSDScarce researchPrevalence, Correlates, and Psychiatric Burden of Prolonged Grief Disorder in U.S. Military Veterans: Results From a Nationally Representative Study
Na P, Fischer I, Shear K, Pietrzak R. Prevalence, Correlates, and Psychiatric Burden of Prolonged Grief Disorder in U.S. Military Veterans: Results From a Nationally Representative Study. American Journal Of Geriatric Psychiatry 2023, 31: 543-548. PMID: 36878740, PMCID: PMC11143540, DOI: 10.1016/j.jagp.2023.02.007.Peer-Reviewed Original ResearchConceptsIndependent risk factorMajor depressive disorderUnited States veteransCoronavirus disease 2019Substance use disordersPost-traumatic stress disorderGrief disorderAdverse childhood experiencesNon-natural causesU.S. military veteransPoint prevalenceNationally Representative StudyFemale sexNational HealthRepresentative studyRisk factorsDepressive disorderPsychiatric burdenDisease 2019States veteransAdditional adjustmentPsychiatric disordersProlonged Grief DisorderUse disordersU.S. veteransSex-specific risk and resilience correlates of suicidal ideation in U.S. military veterans
Stefanovics E, Potenza M, Tsai J, Nichter B, Pietrzak R. Sex-specific risk and resilience correlates of suicidal ideation in U.S. military veterans. Journal Of Affective Disorders 2023, 328: 303-311. PMID: 36775254, DOI: 10.1016/j.jad.2023.02.025.Peer-Reviewed Original ResearchConceptsSuicidal ideationMale veteransFemale veteransU.S. military veteransRisk factorsGender-specific risk factorsPrevalence of SISex-specific riskMilitary veteransDifferent risk factorsAlcohol use disorderLow psychological resilienceMultivariable analysisNational HealthRepresentative sampleUse disordersU.S. veteransVeterans StudySuicide preventionTreatment effortsVeteransLow purposeStrongest correlatePrevalenceIdeationIdentifying significant correlates of purpose in life in older US military veterans: results from the national health and resilience in veterans study.
Fischer I, Feldman D, Tsai J, Harpaz-Rotem I, Lucas K, Schulenberg S, Pietrzak R. Identifying significant correlates of purpose in life in older US military veterans: results from the national health and resilience in veterans study. International Psychogeriatrics 2023, 35: 560-565. PMID: 36715004, DOI: 10.1017/s1041610222001223.Peer-Reviewed Original ResearchConceptsUS military veteransNational HealthMilitary veteransSignificant correlatesOlder US veteransAdverse health outcomesModifiable psychosocial factorsAdverse outcomesElastic net analysisUS veteransDepressive symptomsPsychosocial factorsHealth outcomesVeterans StudyPsychosocial variablesTreatment effortsCognitive outcomesCross-sectional dataVeteransOutcomesSocial supportCommunity integrationImportant correlatesHealthCorrelatesPrevalence, characteristics, and health burden of rheumatoid arthritis in the U.S. veteran population
Morse J, Afari N, Norman S, Guma M, Pietrzak R. Prevalence, characteristics, and health burden of rheumatoid arthritis in the U.S. veteran population. Journal Of Psychiatric Research 2023, 159: 224-229. PMID: 36746059, DOI: 10.1016/j.jpsychires.2023.01.039.Peer-Reviewed Original ResearchConceptsAlcohol use disorderSubthreshold posttraumatic stress disorderPosttraumatic stress disorderRheumatoid arthritisMental health burdenHealth burdenU.S. veteransMedical conditionsSomatic symptomsLifetime alcohol use disorderMale U.S. veteransConditions/symptomsSevere somatic symptomsU.S. veteran populationU.S. military veteransMultivariable analysisTrauma burdenIndependent associationNational HealthRepresentative sampleCurrent insomniaPsychiatric characteristicsUse disordersVeteran populationGreater severity
2022
Dissecting the epigenomic differences between smoking and nicotine dependence in a veteran cohort
Nagamatsu S, Pietrzak R, Xu K, Krystal J, Gelernter J, Montalvo‐Ortiz J. Dissecting the epigenomic differences between smoking and nicotine dependence in a veteran cohort. Addiction Biology 2022, 28: e13259. PMID: 36577721, DOI: 10.1111/adb.13259.Peer-Reviewed Original ResearchConceptsSmoking statusNicotine dependenceVeteran cohortNon-current smokersSerious public health issueNovel treatment strategiesPublic health issueUS military veteransEpigenome-wide association studiesCurrent smokersTreatment strategiesFagerström TestNicotine addictionSmokingHealth issuesRole of epigeneticsMilitary veteransMethylationEPIC BeadChip arraySmokersContinuous variablesF2RL3 geneCohortBiomarkersBeadChip arrayPrevious findingsGenetic liability to suicidal thoughts and behaviors and risk of suicide attempt in US military veterans: moderating effects of cumulative trauma burden
Nichter B, Koller D, De Angelis F, Wang J, Girgenti M, Na P, Hill M, Norman S, Krystal J, Gelernter J, Polimanti R, Pietrzak R. Genetic liability to suicidal thoughts and behaviors and risk of suicide attempt in US military veterans: moderating effects of cumulative trauma burden. Psychological Medicine 2022, 53: 6325-6333. PMID: 36444557, DOI: 10.1017/s0033291722003646.Peer-Reviewed Original ResearchConceptsPolygenic risk scoresUS military veteransLifetime suicide attemptsSuicide attemptsTrauma exposureTrauma burdenGenetic liabilityMilitary veteransDrug repurposing analysisPopulation-based sampleCumulative trauma exposureLifetime trauma exposureLow trauma exposureSuicide prediction modelsChronic inflammationInflammatory processNervous system developmentRisk scorePsychiatric characteristicsSuicidal behaviorExposure interactionsLarge genome-wide association studiesHigh levelsVeteransSuicidalityPrevalence and Clinical Characteristics of Recreational and At-Risk/Problematic Gambling in a National Sample of U.S. Military Veterans
Stefanovics E, Potenza M, Tsai J, Pietrzak R. Prevalence and Clinical Characteristics of Recreational and At-Risk/Problematic Gambling in a National Sample of U.S. Military Veterans. Journal Of Gambling Studies 2022, 39: 1077-1097. PMID: 36378356, DOI: 10.1007/s10899-022-10165-z.Peer-Reviewed Original ResearchConceptsCurrent psychiatric diagnosisU.S. military veteransUse disordersPsychiatric diagnosisMilitary veteransU.S. veteransDrug use disordersMental health treatmentSubstance use disordersChi-square testClinical characteristicsTrauma burdenNational HealthAdjusted associationsRoutine screeningClinical measuresRecreational gamblingCurrent prevalenceMale veteransHealth treatmentHigher household incomeSuicidal ideationVeterans StudyLogistic regressionExtensive involvementTreatment response trajectories in residential PTSD programs for veterans: A national cohort investigation
Grau P, Sripada R, Pietrzak R, Ganoczy D, Harpaz-Rotem I. Treatment response trajectories in residential PTSD programs for veterans: A national cohort investigation. Journal Of Anxiety Disorders 2022, 92: 102645. PMID: 36334317, DOI: 10.1016/j.janxdis.2022.102645.Peer-Reviewed Original ResearchConceptsEvidence-based psychotherapiesThree-group trajectory modelTreatment outcomesTreatment responseTime of admissionPoor treatment outcomesPoor treatment responseNon-white raceResidential PTSD programsSubset of veteransPTSD treatment outcomesResidential PTSD treatmentPain severityCohort investigationPTSD careNational cohortFull cohortPTSD treatmentTherapeutic gainTreatment dropoutSymptom trajectoriesVeterans AffairsPTSD programTreatment response trajectoriesTreatment trajectories