Cox-2 is needed but not sufficient for apoptosis induced by Cox-2 selective inhibitors in colon cancer cells
Agarwal B, Swaroop P, Protiva P, Raj S, Shirin H, Holt P. Cox-2 is needed but not sufficient for apoptosis induced by Cox-2 selective inhibitors in colon cancer cells. Apoptosis 2003, 8: 649-654. PMID: 14739610, DOI: 10.1023/a:1026199929747.Peer-Reviewed Original ResearchConceptsHCT116 cellsHT29 cellsProtein expressionColon cancer cellsColon cancer cell linesCell numberCOX-2 protein expressionCancer cell linesApoptosisProtein levelsCancer cellsCell linesExpressionSelective inhibitorHT29CellsFlow cytometryCOX-2 protein levelsInhibitorsCOX-2COX-2 expressionHCT116High levelsRoleΜMPhenylacetate induces G1/S arrest and apoptosis in colon cancer cells but antagonizes S-phase specific chemotherapy
Protiva P, Agarwal B, Shimizu M, Weinstein I, Holt P. Phenylacetate induces G1/S arrest and apoptosis in colon cancer cells but antagonizes S-phase specific chemotherapy. Gastroenterology 2003, 124: a463. DOI: 10.1016/s0016-5085(03)82342-9.Peer-Reviewed Original Research