2008
Robustness promotes evolvability of thermotolerance in an RNA virus
McBride RC, Ogbunugafor CB, Turner PE. Robustness promotes evolvability of thermotolerance in an RNA virus. BMC Ecology And Evolution 2008, 8: 231. PMID: 18694497, PMCID: PMC2518931, DOI: 10.1186/1471-2148-8-231.Peer-Reviewed Original ResearchConceptsGenetic robustnessEfficacy of selectionNew habitatsEvolutionary biologyVirus adaptabilityLaboratory populationsMutational changesNew nichesEvolvabilityRNA virusesFace of perturbationsGreater toleranceThermotoleranceRobust clonesNovel environmentClonesBiological systemsBalance of robustnessFuture adaptationUnderlying mechanismHabitatsNicheBiologyGreater resistancePopulation
2005
Evolution of Mutational Robustness in an RNA Virus
Montville R, Froissart R, Remold SK, Tenaillon O, Turner PE. Evolution of Mutational Robustness in an RNA Virus. PLOS Biology 2005, 3: e381. PMID: 16248678, PMCID: PMC1275523, DOI: 10.1371/journal.pbio.0030381.Peer-Reviewed Original ResearchConceptsMutational robustnessRNA virusesAccurate genome replicationEvolution of robustnessUnderstanding of evolutionAdaptive evolutionGenetic robustnessPopulation bottleneckingPhenotypic constancyMutation accumulationNatural selectionGenetic variationMutational effectsGenome replicationHigh mutation frequencyMutational changesRandom mutationsMutation rateHost cellsBiological populationsFitness changesMutation frequencyGenomeComplementationVirus